A5100381563- Genomics and Phylogenetic Studies
- Genetic and phenotypic traits in livestock
- Genetic Mapping and Diversity in Plants and Animals
- Bacteriophages and microbial interactions
- Genetic diversity and population structure
- Cancer-related molecular mechanisms research
- RNA and protein synthesis mechanisms
- Plant Virus Research Studies
- Plant Molecular Biology Research
- MicroRNA in disease regulation
- Chromosomal and Genetic Variations
- Plant and Fungal Interactions Research
- Plant Reproductive Biology
- Plant and animal studies
- Plant Diversity and Evolution
- Photosynthetic Processes and Mechanisms
- Plant Disease Resistance and Genetics
- Plant Taxonomy and Phylogenetics
- RNA modifications and cancer
- RNA Research and Splicing
- Inflammasome and immune disorders
- Plant Stress Responses and Tolerance
- Soil Carbon and Nitrogen Dynamics
- Plant Gene Expression Analysis
- Bacterial biofilms and quorum sensing
Zhejiang University
2021-2025
Wuhan Botanical Garden
2023-2025
Chinese Academy of Sciences
2016-2025
Institute of Zoology
2025
University of Chinese Academy of Sciences
2025
China Agricultural University
2008-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2022-2024
Qingdao Agricultural University
2024
Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai)
2023-2024
Xuzhou Medical College
2024
Ulcerative colitis (UC) is a relapsing and remitting inflammatory disease. Probiotics have potential beneficial effect on the prevention of UC onset relapse in clinical trials. Lactobacillus rhamnosus GG (L. GG) shown benefits patients, however, precise mechanisms are unknown. The aim this study to explore extracellular vesicles released from L. (LGG-EVs) dextran sulfate sodium (DSS)-induced propose underlying mechanism LGG-EVs for protecting against colitis. results showed that could...
Abstract Tools for visualizing genomes are essential investigating genomic features and their interactions. Currently, tools designed originally animal mitogenomes plant plastomes used to visualize the mitogens of plants but cannot accurately display specific mitogenomes, such as nonlinear exon arrangement genes, prevalence functional noncoding complex chromosomal architecture. To address these problems, a software package, mitochondrial genome map (PMGmap), was developed using Python...
Milk-derived extracellular vesicles (mEVs) as nanoparticles are being developed novel drug vehicles due to their pivotal role in cell-cell communication. As an important bioactive component milk, little is known about effect on the gut microbiota and intestinal immunity. Therefore, effects of mEVs immunity mice investigated.First, a new method obtain high-yield developed. Afterward, colonic contents from C57BL/6 fed different doses (8 weeks) collected microbial composition via 16S rRNA gene...
ABSTRACT Aim Understanding the spatial distribution of genetic variation within species is a central tenet in evolutionary biology and conservation biology. This study explores how historical demographic processes and/or environmental factors interact to affect contemporary adaptive potential, with specific focus on testing ‘centre‐periphery’ hypothesis (CPH). Location Subtropical China. Taxon Liquidambar. Methods We combined comparative phylogeography, landscape genomics niche modelling...
SUMMARY Understanding the genetic basis of population divergence and adaptation is an important goal in genetics evolutionary biology. However, relative roles demographic history, gene flow, and/or selective regime driving genomic divergence, climatic adaptation, speciation non‐model tree species are not yet fully understood. To address this issue, we generated whole‐genome resequencing data Liquidambar formosana L. acalycina , which broadly sympatric but altitudinally segregated Tertiary...
SUMMARY ‘Living fossils’, that is, ancient lineages of low taxonomic diversity, represent an exceptional evolutionary heritage, yet we know little about how demographic history and deleterious mutation load have affected their long‐term survival extinction risk. We performed whole‐genome sequencing population genomic analyses on Dipteronia sinensis D. dyeriana , two East Asian Tertiary relict trees. found large‐scale genome reorganizations identified species‐specific genes under positive...
Subtilases (SBTs), which belong to the serine peptidases, control plant development by regulating cell wall properties and activity of extracellular signaling molecules, affect all stages life cycle, such as seed germination, responses biotic abiotic environments. In this study, 146 Gossypium hirsutum, 138 barbadense, 89 arboreum 84 raimondii SBTs were identified divided into six subfamilies. Cotton are unevenly distributed on chromosomes. Synteny analysis showed that members SBT1 SBT4...
In this study, we compared the transcriptome of longissimus dorsi muscle between Guizhou Xiang pigs (XP) and Western commercial Large White (LW), which show diffirent meat quality them. terms traits, pH 45 min, color score, backfat thickness, intramuscular fat (IMF) content were higher in than (P < 0.01), while drip loss, lean percentage, shear force, area lower that 0.01). Nutrients such as monounsaturated fatty acid (MUFA), total amino acids (TAA), delicious (DAA) essential (EAA) pigs,...
Summary The Chinese indigenous pig breeds in the Taihu Lake region are most prolific world. In this study, we investigated genetic diversity and population structure of six breeds, including Meishan, Erhualian, Mi, Fengjing, Shawutou Jiaxing Black, using whole‐genome SNP data. A high with proportions polymorphic markers ranging from 0.925 to 0.995 was exhibited by pigs region. allelic richness expected heterozygosity also were calculated indicated that Meishan breed greatest, whereas...
Summary Humans have domesticated diverse species from across the plant kingdom; however, our current understanding of domestication is largely founded on major cereal crops. Here, we examine evolutionary processes and genetic basis underlying water caltrop ( Trapa spp., Lythraceae), a traditional, yet presently underutilized non‐cereal crop that sustained early Chinese agriculturalists. We generated chromosome‐level genome assembly tetraploid T. natans , then divided allotetraploid into two...
Plant Knotted1-like homeobox (KNOX) genes encode homeodomain-containing transcription factors. In rice (Oryza sativa L.), little is known about the downstream target of KNOX Class II subfamily proteins. Here we generated chromatin immunoprecipitation (ChIP)-sequencing datasets for HOS59, a member subfamily, and characterized genome-wide binding sites HOS59. We conducted trait ontology (TO) analysis 9705 identified genes, found that multiple TO terms are related to plant structure morphology...
Here, we present a high-quality chromosome-scale genome assembly (2.19 Gb) and annotation of Tetrastigma hemsleyanum, perennial herbaceous liana native to subtropical China with diverse medicinal applications. Approximately 73% the was comprised transposable elements (TEs), which long terminal repeat retrotransposons (LTR-RTs) were predominant group (69% genome). The size increase T. hemsleyanum (relative Vitis species) mostly due proliferation LTR-RTs. Of different modes gene duplication...
Tube-like outgrowths from root epidermal cells, known as hairs, enhance water and nutrient absorption, facilitate microbial interactions, contribute to plant anchorage by expanding the surface area. Genetically regulated strongly influenced environmental conditions, longer hairs generally correlating with increased stress resistance. Wheat, a globally predominant crop pivotal for human nutrition, necessitates identification of long hair genotypes their regulatory genes capture yield...
Digital therapeutics (DTx) is an emerging and groundbreaking medical intervention that utilizes health software to treat or alleviate various diseases, disorders, conditions, injuries. Although the potential of digital therapy enormous, it still in its nascent stage faces multiple challenges obstacles. The purpose this study provide overview all DTx-related clinical trials ClinicalTrials.gov promote advancement DTx.
This study was designed to investigate the genetic basis of growth and egg traits in Dongxiang blue-shelled chickens White Leghorn chickens. In this study, we employed a reduced representation sequencing approach called genotyping by genome reducing detect genome-wide SNPs 252 The chicken breed has many specific is characterized eggs, black plumage, skin, bone organs. an egg-type with high productivity. As multibreed association studies (GWASs) can improve precision due less linkage...
Abstract The study of mutational processes in somatic genomes has gained recent momentum, uncovering a wide array endogenous and exogenous factors associated with changes. However, the overall landscape germline mutations across tree life evolutionary driving forces are rather unclear. In this study, we analyzed single-stranded RNA (ssRNA) viruses which known to jump between different hosts divergent environments. We found that spectra ssRNA differ significantly mainly their genetic...