A5079154529- Nutritional Studies and Diet
- Diet and metabolism studies
- Fatty Acid Research and Health
- Nuts composition and effects
- Antioxidant Activity and Oxidative Stress
- Gut microbiota and health
- Probiotics and Fermented Foods
- Consumer Attitudes and Food Labeling
- Horticultural and Viticultural Research
- Plant Physiology and Cultivation Studies
- Cholesterol and Lipid Metabolism
- Cancer, Lipids, and Metabolism
- Agriculture Sustainability and Environmental Impact
- Adipokines, Inflammation, and Metabolic Diseases
- Pregnancy and Medication Impact
- Muscle metabolism and nutrition
- Eicosanoids and Hypertension Pharmacology
- Traumatic Brain Injury Research
- Folate and B Vitamins Research
- Meat and Animal Product Quality
- Obesity, Physical Activity, Diet
- Phytoestrogen effects and research
- Aquaculture Nutrition and Growth
- Machine Learning in Bioinformatics
- Musculoskeletal pain and rehabilitation
European Bioinformatics Institute
2025
Pennsylvania State University
2014-2024
Detroit Receiving Hospital
2014-2024
Rehabilitation Institute of Michigan
2024
Wayne State University
2014-2024
West Virginia University
2023
Fleming College
2018-2019
University of Georgia
2016
Park University
2016
Program for Appropriate Technology in Health
2014
Abstract We have previously shown that in vivo nasal challenge with diesel exhaust particles (DEP) induces both quantitative and qualitative changes local IgE production stimulates generalized cytokine production. now investigated the combined effects of intranasal DEP plus ragweed allergen on humoral immune responses. collected lavages from sensitized subjects at different times after challenge. As compared alone, induced markedly higher ragweed-specific but not total levels or...
Lifestyle modification is recommended in women with polycystic ovary syndrome (PCOS) prior to conception but there are few randomized trials support its implementation or benefit.This study aimed determine the relative efficacy of preconception intervention on reproductive and metabolic abnormalities overweight/obese PCOS.This was a controlled trial infertility treatment at Academic Health Centers due PCOS, age 18-40 y body mass index 27-42 kg/m(2).Women were randomly assigned receive either...
The erythrocyte membrane content of eicosapentaenoic acid (EPA) and docosahexaenoic (DHA), which constitutes the omega-3 index (O3I), predicts cardiovascular disease mortality. amount EPA+DHA needed to achieve a target O3I is poorly defined, as are determinants response change in intake. objective this study was develop predictive model supplementation healthy adults, specifically identifying factors that determine response.A randomized, placebo-controlled, double-blind, parallel-group...
The repertoire of modifications to bile acids and related steroidal lipids by host microbial metabolism remains incompletely characterized. To address this knowledge gap, we created a reusable resource tandem mass spectrometry (MS/MS) spectra filtering 1.2 billion publicly available MS/MS for bile-acid-selective ion patterns. Thousands are distributed throughout animal human bodies as well cultures. We employed library identify polyamine amidates, prevalent in carnivores. They present...
Context: Polycystic ovary syndrome (PCOS) is associated with reduced health-related quality of life (HRQOL) and increased prevalence depressive anxiety disorders. The impact PCOS-specific treatments on these co-morbidities unclear. Objective: To assess the weight loss decreasing hyperandrogenism HRQOL mood disorders in women PCOS. Design/Setting/Participants: A secondary analysis a randomized controlled trial (OWL-PCOS) preconception treatment conducted at two academic centers (age, 18–40...
Background Avocados are a nutrient‐dense source of monounsaturated fatty acids ( MUFA ) that can be used to replace saturated SFA in diet lower low density lipoprotein cholesterol LDL ‐C). Well‐controlled studies lacking on the effect avocado consumption cardiovascular disease CVD risk factors. Methods and Results A randomized, crossover, controlled feeding trial was conducted with 45 overweight or obese participants baseline LDL‐C 25th 90th percentile. Three cholesterol‐lowering diets (6%...
Background Evidence consistently shows that almond consumption beneficially affects lipids and lipoproteins. Almonds, however, have not been evaluated in a controlled‐feeding setting using diet design with only single, calorie‐matched food substitution to assess their specific effects on cardiometabolic risk factors. Methods Results In randomized, 2‐period (6 week/period), crossover, study of 48 individuals elevated LDL ‐C (149±3 mg/dL), cholesterol‐lowering almonds (1.5 oz. almonds/day) was...
Abstract OBJECTIVES. We explored the clinical application of goal-directed therapy in community-based rehabilitation from perspective clients with traumatic brain injury (TBI), their significant others, and treating occupational therapists. METHOD. Twelve people TBI others completed an outpatient, goal-directed, 12week program. Semistructured interviews 12 participants, 10 3 therapists involved delivering programs experiences therapy. RESULTS. Participants, described positively, expressing...
Objective To determine the effect of diets low in saturated fatty acids and high monounsaturated (MUFA) or polyunsaturated on body composition participants at risk for metabolic syndrome (MetS). Methods This study was a randomized, crossover, controlled feeding study. Participants ( n = 101, ages 49.5 ± 1.2, BMI 29.4 0.4 kg/m 2 ) were randomized to five isocaloric containing treatment oils: Canola, CanolaOleic, CanolaDHA, Corn/Safflower, Flax/Safflower. Each diet period 4 weeks followed by...
Because of efforts to decrease trans fatty acids (TFA) in the food supply, intake should be assessed population establish a baseline TFA intake. The 1999-2002 National Health and Nutrition Examination Survey (NHANES) was used identify benchmark for estimated by mean, median, quintile intake, data were weighted using NHANES 4-year sample weights. main outcome measures included grams per day percentage energy top 25 sources TFA. Data are reported 16,669 individuals ≥ 3 years age. Median 2.3 %...
Background Consumption of almonds or dark chocolate and cocoa has favorable effects on markers coronary heart disease; however, the combined have not been evaluated in a well‐controlled feeding study. The aim this study was to examine individual consumption disease risk. Methods Results A randomized controlled, 4‐period, crossover, trial conducted overweight obese individuals aged 30 70 years. Forty‐eight participants were randomized, 31 completed entire Each diet period 4 weeks long,...
Background. Current oral rotavirus vaccines perform suboptimally in resource-poor settings. We investigated the effect of an additional dose and later schedule on immunogenicity monovalent vaccine (RV1) a developing country. Methods. Infants received RV1 at 6 10, 10 14, or 6, 14 weeks age. The primary objective was to compare antirotavirus immunoglobulin A (IgA) seroconversion 18 6/10/14 arm cumulative (highest result weeks) 6/10 arm. Results. Overall, 480 (76.2%) 630 randomized infants...
Scope Probiotics can modulate immunity and reduce upper respiratory tract infections (URTI) in humans; however few studies have examined both outcomes the same trial. The goal of current study was to investigate effect Bifidobacterium animalis subsp. lactis BB‐12, on natural killer (NK) T‐cell function conjunction with self‐reported cold/flu healthy adults. Methods results In a randomized, partially blinded, four‐period crossover study, adults ( n = 30) were recruited, received four...