A5026092619- Systemic Lupus Erythematosus Research
- Rheumatoid Arthritis Research and Therapies
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Peripheral Neuropathies and Disorders
- Vasculitis and related conditions
- Long-Term Effects of COVID-19
- Dermatological and COVID-19 studies
- Autoimmune and Inflammatory Disorders Research
- Liver Diseases and Immunity
- COVID-19 and healthcare impacts
- Viral Infections and Immunology Research
- Spondyloarthritis Studies and Treatments
- Biosimilars and Bioanalytical Methods
- Cardiomyopathy and Myosin Studies
- Lymphoma Diagnosis and Treatment
- Atherosclerosis and Cardiovascular Diseases
- Cytokine Signaling Pathways and Interactions
- Immunodeficiency and Autoimmune Disorders
- Renal Diseases and Glomerulopathies
- Bone and Joint Diseases
- Inhalation and Respiratory Drug Delivery
- Viral-associated cancers and disorders
- Musculoskeletal synovial abnormalities and treatments
- COVID-19 Impact on Reproduction
Hospital Privado
2023
Servicio Diabetología Hospital Córdoba
2018-2022
University of California, San Francisco
2022
Digital Research Alliance of Canada
2021
Psoriasis Association
2021
Universidad Nacional de Córdoba
2012-2021
Systemic lupus erythematosus (SLE), a complex and heterogeneous autoimmune disease, represents significant challenge for both diagnosis treatment. Patients with SLE in Latin America face special problems that should be considered when therapeutic guidelines are developed. The objective of the study is to develop clinical practice American patients lupus. Two independent teams (rheumatologists experience management methodologists) had an initial meeting Panama City, Panama, April 2016. They...
Abstract Objectives Although evidence is accumulating globally, data on outcomes in rheumatic disease and COVID-19 Ireland are limited. We used from the Global Rheumatology Alliance (C19-GRA) to describe time-varying for people with Ireland. Methods Data entered into C19-GRA provider registry between 24 March 2020 9 July 2021 were analysed. Differences likelihood of hospitalization mortality according demographic clinical variables investigated using Chi-squared test or Fisher’s exact test,...
Introducción: conocer la seguridad de las drogas actualmente disponibles para el tratamiento enfermedades reumáticas es muy importante al momento tomar decisiones terapéuticas objetivas e individualizadas en consulta médica diaria. Asimismo, datos vida real amplían conocimiento revelado por los ensayos clínicos.
 Objetivos: describir eventos adversos (EA) reportados, estimar su frecuencia identificar factores relacionados con desarrollo.
 Materiales y métodos: se utilizaron...
To describe obstetric outcomes based on COVID-19 vaccination status, in women with rheumatic and musculoskeletal diseases (RMDs) who developed during pregnancy.
Background/Objective This study describes the impact of immunomodulatory and/or immunosuppressive (IM/IS) drugs in outcomes COVID-19 infection a cohort patients with immune-mediated inflammatory diseases (IMIDs). Methods Adult IMIDs confirmed SARS-CoV-2 were included. Data reported by treating physician between August 13, 2020 and July 31, 2021. Sociodemographic data, comorbidities, DMARDs, as well clinical characteristics, complications, treatment infection, recorded. Descriptive analysis...
Background: SARS CoV-2 infection has recently burst onto the global scene, and knowledge of course this in patients with rheumatic diseases receiving immunomodulatory treatment is still insufficient. The Argentine Society Rheumatology (SAR) designed a national registry called SAR-COVID order to get assess our reality. Objectives: To identify particular characteristics COVID-19 Argentina (SAR-COVID Registry), compare them data reported at Latin American Global level (Global International...
<h3>Background</h3> Neonatal lupus (NL) is a disease in children of mothers who have specific anti-Ro/La IgG autoantibodies by passive transplacental transfer. LN characterized skin and cardiac involvement, as well cytopenias, hepatic or neurological manifestations. NL can be diagnosed intra-uterus neonatal period, being self-limiting several months irreversible. Congenital heart block (CHB) structurally normal heart, perhaps the most serious manifestation with an estimated mortality rate...
Background: Psoriatic arthritis (PsA) is a chronic inflammatory disease associated with higher risk of cardiovascular events and metabolic syndrome. The inflammation not only accelerates atherosclerosis, but also may influence (CV) factors such as lipid profile, blood pressure insulin resistance. Lipid profile has previously been studied in PsA, however this association still controversial. Objectives: To study the frequency altered patients PsA its activity. Methods: We all diagnosis who...
We described a 35 years old female, who developed Chronic inflammatory demyelinating polyneuropathy as neurologic commitment during the early diagnosis in Systemic Lupus Erithematosus (SLE). While neuropsychiatric has variable prevalence SLE, association that we describe is infrequent and it important concerns its treatment.
<h3>Background</h3> Since SLE tends to occur during the productive years of life, cost disease derives not only from direct health expenditures but also impact has on work productivity. <h3>Objectives</h3> To describe productivity and assess factors influencing this outcome measure. <h3>Methods</h3> We studied 225 patients (1987 ACR criteria), age ≥16 years. Work was assessed with WPAI:Specific Health Problem for SLE. The WPAI yeilds four scores: % time missed, impairment at work, overall...
<h3>Background</h3> SLE can inflict significant morbidity that is reflected not only in the patients9 overall clinical status but also their ability to work. <h3>Objectives</h3> To examine cumulative rate and factors associated with work disability patients Province of Cόrdoba, Argentina <h3>Methods</h3> We studied 225 patients, age >16 years. Work was defined by self-report working because health status. The estimated Kaplan-Meier method. relationship between socioeconomic-demographic,...
<h3>Background</h3> Patients with rheumatic diseases may present more severe SARS-CoV-2 infection compared to the general population. However, in some studies, hospitalization and mortality due COVID-19 were lower patients axial spondyloarthritis (axSpA) other diseases. <h3>Objectives</h3> To assess severity of axSpA from SAR-COVID registry, comparing them rheumatoid arthritis (RA), determine factors associated poor outcomes death. <h3>Methods</h3> ≥18 years old national registry diagnosis...
<h3>Background</h3> The clinical manifestations of patients with rheumatic diseases are highly heterogeneous. appearance adverse events (AEs) related to the treatments received for these considerably increases morbidity and mortality patients. This is why obtaining real-world data on AEs analyzing their causes paramount. BIOBADASAR registry has from 5,676 over ten years follow-up. Classifying in treatment biological drugs into subgroups different phenotypes through unsupervised grouping...
<h3>Background</h3> Major Cardiovascular Adverse Events (MCAE) are a concern in autoimmune diseases. Rheumatoid Arthritis (RA) and psoriasis arthritis (PsA) diseases where inflammation plays vital role developing the disease producing short- long-term damage. The TNF alpha significant inflammation. JAK/STAT signaling pathway is an essential regulatory cascade of intracellular processes used treating these conditions. It crucial to evaluate effect treatments on comorbidities associated with...
Mofetil mycophenolate (MM) is an immunosuppressive agent that was initially used to prevent rejection in solid organ transplantation, and later treat systemic autoimmune diseases. In Systemic Lupus Erythematosus (SLE) it for the treatment of Nephropathy (LN) now considered important alternative LN refractory other drugs as well induction therapy with promising results lower toxicity1-3. The first studies were limited describing series small numbers patients where MM Cyclophosphamide (CF)...
La CIDP es un desorden autoinmune adquirido contra mielina originando polineuropatía simétrica, con debilidad muscular o sin alteración sensitiva en las extremidades, curso crónico progresivo remisiones y recaídas, infrecuente LES. Caso clínico: Mujer, 35 años. APP: Fotosensibilidad Raynaud desde 10/2016, decorticación pleural por empiema 11/16. En 3/2017 presenta diarrea, vómitos, parestesias manos pies de 1 semana evolución disminución fuerza, fatiga temblor lengua. EF: fuerza distal...
La Artritis Reumatoide (AR) es una enfermedad autoinmune sistémica, inflamatoria, crónica, degenerativa y progresiva, caracterizada por la poliartritis periférica, generalmente simétrica de articulaciones pequeñas. Sociedad Argentina Reumatología incluye en definición comprometidas a las diartrodiales como temporomandibular. Provoca desórdenes dolorosos manos pies, deformidades articulares múltiples discapacidad, además se acompaña manifestaciones inflamación sitémica compromiso...
The therapeutic approach of patients with two or more autoimmune diseases is quite a challenge, especially when the treatment one them, can precipitate progression other. Even though association rheumatoid arthritis (RA) and primary biliary cholangitis (PBC) rare; both coexist, use methotrexate other hepatotoxic drugs should be used caution. With most widespread indication biologic disease- modifying antirheumatic (bDMARDs) some reports RA PBC treated etanercept, infliximab, rituximab,...