A5109803403- Systemic Lupus Erythematosus Research
- Bone health and osteoporosis research
- Rheumatoid Arthritis Research and Therapies
- Hip and Femur Fractures
- Monoclonal and Polyclonal Antibodies Research
- Bone Metabolism and Diseases
- Atherosclerosis and Cardiovascular Diseases
- Bone health and treatments
- Renal Diseases and Glomerulopathies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Autoimmune and Inflammatory Disorders Research
- T-cell and B-cell Immunology
- Vitamin D Research Studies
- Bone fractures and treatments
- Salivary Gland Disorders and Functions
- Dermatological and Skeletal Disorders
- Psoriasis: Treatment and Pathogenesis
- Autoimmune Bullous Skin Diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Platelet Disorders and Treatments
- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Systemic Sclerosis and Related Diseases
- Adrenal Hormones and Disorders
- Health and Medical Education
Centro Universitário das Faculdades Metropolitanas Unidas
2025
Asociación Colombiana de Diabetes
2023
Municipality of Medellín
2009-2019
Fundacion Instituto de Reumatologia Fernando Chalem
2013-2018
Universidad Francisco Marroquín
2015-2016
Hospital de Clínicas da Unicamp
2016
Universidade Estadual de Campinas (UNICAMP)
2016
Brown University
2016
University of Carabobo
2016
Clínica CES
2015-2016
Abstract Objective . To assess the frequency of methotrexate (MTX)‐induced pancytopenia in rheumatoid arthritis (RA). Methods A MEDLINE literature search was conducted to identify articles published during last 15 years (1980–1995) that presented data on MTX‐associated pancytopenia. Two case reports our own experience are also presented. In addition, examined risk factors associated with MTX‐related were identified. Results total 70 patients related MTX therapy identified (68 reported...
Systemic lupus erythematosus (SLE), a complex and heterogeneous autoimmune disease, represents significant challenge for both diagnosis treatment. Patients with SLE in Latin America face special problems that should be considered when therapeutic guidelines are developed. The objective of the study is to develop clinical practice American patients lupus. Two independent teams (rheumatologists experience management methodologists) had an initial meeting Panama City, Panama, April 2016. They...
The objective of this consensus is to update the recommendations for treatment hand, hip, and knee osteoarthritis (OA) by agreeing on key propositions relating management OA, identifying critically appraising research evidence effectiveness treatments generating based a combination available expert opinion 18 countries America. Recommendations were developed group 48 specialists rheumatologists, members other medical disciplines (orthopedics physiatrists), three patients, one each location...
PROBLEM: Immunization with β 2 ‐glycoprotein I (β GPI) induces antiphospholipid antibodies (aPL) in normal mice and rabbits. Recently we reported early onset of autoimmunity MRL/++ following immunization GPI. There is a close association between aPL thrombosis, recurrent fetal loss, intrauterine growth retardation. In this study evaluated the effect GPI‐induced on pregnancy outcomes an inbred strain (PL/J). METHOD: Three groups seven‐week‐old female PL/J (12 per group) were studied. Group A...
Objective To compare clinical effectiveness between tocilizumab and tumor necrosis factor inhibitors (TNFi) in patients with rheumatoid arthritis (RA) inadequate response to conventional synthetic disease‐modifying antirheumatic drugs initiating biologic therapy. Methods Patients prescribed (intravenous) or TNFi were prospectively observed routine practice for 52 weeks across 158 sites 26 countries. The primary observation was the change from baseline Disease Activity Score based on 28...
Since ethnic differences in the disease expression of systemic lupus erythematosus (SLE) have been recognized, we compared clinical and serological features two different groups patients with SLE. The study population consisted 222 African-American 300 Latin American (Colombian) SLE patients. Clinical, demographic, laboratory data were obtained by chart review using a standard collection form. more commonly manifested discoid skin lesions, pulmonary fibrosis, pleuritis, less...
Background Latin America is a heterogeneous region made up of different populations, cultures, latitudes, altitudes, and immigrants from areas ethnic groups. Objective The purpose this study to describe the clinical demographic profile patients with osteoarthritis (OA) evaluated by selected group rheumatologists in 13 American countries. Methods A descriptive, observational, cross-sectional was conducted countries symptomatic OA. Data were collected over 3-month period using an ad hoc...
Obesity is a serious and prevalent problem in dogs. The causes are multifactorial, but owners play key role so this paper reports the development evaluation of health pack designed to help manage weight their was informed by previous research, behavior change theory (i.e., COM-B model), interviews with 12 veterinary professionals identify challenges potential solutions. Six workshops total 28 dog provided feedback on initial ideas. included information importance management, how weigh assess...
ABSTRACT Oral squamous cell carcinoma (OSCC) is still being late diagnosed in Brazilian population, which implies worst survival rates. The present clinical case aimed to report a 64-year-old female patient that was referred the university with main complain of lump on tongue. During anamnesis, she did not addictions, such as smoking or drinking. Extra-oral physical examination revealed an increase and stiffening submandibular lymph nodes. Intraorally, it could be observed extensive...
Prolactin (PRL) has been shown to have immunoregulatory effects on a variety of immune responses. Its effect B cell responses is suggested by in vitro data demonstrating direct activation and differentiation, also vivo biphasic stimulation antibody production sheep red blood cells. In addition, it both animal models patients with hyperprolactinemia that PRL may influence the presence certain autoantibodies. The objective this work was study induction immunoglobulins, anti-DNA rheumatoid...
Introducción: la osteoporosis es enfermedad ósea metabólica más común. Entre sus causas secundarias se encuentra deficiencia de vitamina D (VD), cual predispone además a fracturas por fragilidad e incrementa el riesgo caídas. También confiere un incrementado desarrollar cardiovascular, diabetes mellitus tipo 1 y 2.
 Objetivo: objetivo principal del estudio fue determinar los niveles en población correlacionarlos con diferentes variables clínicas, laboratorio densitométricas.
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