A5084478582- Rheumatoid Arthritis Research and Therapies
- Systemic Lupus Erythematosus Research
- Autoimmune and Inflammatory Disorders Research
- Osteoarthritis Treatment and Mechanisms
- Spondyloarthritis Studies and Treatments
- Salivary Gland Disorders and Functions
- Systemic Sclerosis and Related Diseases
- Vasculitis and related conditions
- Atherosclerosis and Cardiovascular Diseases
- Immunodeficiency and Autoimmune Disorders
- Inflammatory mediators and NSAID effects
- Autoimmune Bullous Skin Diseases
- Galectins and Cancer Biology
- Inflammatory Myopathies and Dermatomyositis
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Monoclonal and Polyclonal Antibodies Research
- Salivary Gland Tumors Diagnosis and Treatment
- Orthopedic Surgery and Rehabilitation
- Otitis Media and Relapsing Polychondritis
- Lymphoma Diagnosis and Treatment
- Hepatitis C virus research
- Chronic Lymphocytic Leukemia Research
- Biosimilars and Bioanalytical Methods
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Psoriasis: Treatment and Pathogenesis
Hospital General de Agudos Dr. TEODORO ALVAREZ
2014-2023
Trauma Hospital of Brno
2015-2022
Pfizer (United States)
2017
El Hospital General de Agudos Carlos G. Durand
2006-2017
Brown University
2015-2016
Hospital de Clínicas da Unicamp
2015-2016
Universidade Estadual de Campinas (UNICAMP)
2015-2016
Universidad Francisco Marroquín
2016
University of Carabobo
2016
Universidad Católica San Pablo
2015
<h3>Objectives</h3> To evaluate treatment with the peptide-based agent, Lupuzor, in a double-blind, randomised, placebo-controlled study of patients systemic lupus erythematosus. <h3>Methods</h3> Patients who met ≥4 American College Rheumatology criteria, had score ≥6 on Systemic Lupus Erythematosus Disease Activity Index 2000 (SLEDAI-2K) and did not have an A British Isles Assessment Group (BILAG)-2004 scale were eligible. 149 intention-to-treat (ITT) randomly assigned to receive Lupuzor...
The objective of this consensus is to update the recommendations for treatment hand, hip, and knee osteoarthritis (OA) by agreeing on key propositions relating management OA, identifying critically appraising research evidence effectiveness treatments generating based a combination available expert opinion 18 countries America. Recommendations were developed group 48 specialists rheumatologists, members other medical disciplines (orthopedics physiatrists), three patients, one each location...
To compare the clinical, demographic, and serologic characteristics treatment of patients diagnosed with ankylosing spondylitis (AS) from Europe (EU) Latin America (LA).We included 3439 national registries: Spanish Registry Spondyloarthritis (REGISPONSER), Belgian registry (ASPECT), American Spondyloarthropathies (RESPONDIA). We selected diagnosis AS who met modified New York classification criteria. Demographic, disease activity, functional, metrological measurement data were recorded....
The objective of this study was to assess the prevalence rheumatoid arthritis (RA) in population a city 70,000 inhabitants located Buenos Aires, Argentina.Based on hypothesis that RA is an underdiagnosed disease Argentina, capture-recapture method applied. A local registry patients Luján City taken as primary source; telephone survey specifically carried out secondary source information. Patients suspected having were referred hospital be examined by team 12 rheumatologists. Anamnesis and...
Background Latin America is a heterogeneous region made up of different populations, cultures, latitudes, altitudes, and immigrants from areas ethnic groups. Objective The purpose this study to describe the clinical demographic profile patients with osteoarthritis (OA) evaluated by selected group rheumatologists in 13 American countries. Methods A descriptive, observational, cross-sectional was conducted countries symptomatic OA. Data were collected over 3-month period using an ad hoc...
Abstract Objectives The need for glucocorticoid-sparing drugs (GCSD) remains an important issue and is unmet in the treatment of polymyalgia rheumatica (PMR). We therefore aimed to assess effectiveness safety methotrexate (MTX) leflunomide (LEF) daily clinical practice PMR patients from Argentina. Methods A multicentre observational study (medical records review) seen between 2007 2023, who had at least three months follow-up after starting a GCSD, either MTX or LEF, was performed. Results...
In Brief Objectives: The objectives of this study were to evaluate the frequency and characteristics peripheral musculoskeletal manifestations in polymyalgia rheumatica (PMR), if PMR with synovitis represents a subset more severe disease, examine for clinical laboratory at onset that might later predict rheumatoid arthritis (RA). Patients Methods: diagnosed according 1982 Chuang criteria. followed up between 1990 2002. following during follow considered: synovitis, distal extremity swelling...
Abstract Background Globally, osteoarthritis (OA) is the third condition associated with disability. There still poor treatment in OA but science holds key to finding better treatments and a cure. It essential learn what’s important patients from them implement most effective management. The Patients Task Force, conducted Global Patient Perception Survey (GOAPPS)-the first global survey made by analize quality of life (QoL) & patient perceptions care. goal was collect data on patients’...
Objective. To assess the relationship between work productivity with disease activity, functional capacity, life quality and radiological damage in patients rheumatoid arthritis (RA). Methods. The study included consecutive employed RA (ACR'87), aged over 18. Demographic, disease-related, work-related variables were determined. reduction of was assessed by WPAI-RA. Results. 90 evaluated, 71% women. Age average is 50 years old, DAS28 4, RAQoL 12. Median SENS 18 HAQ-A 0.87. Mean absenteeism...
The aim of the present study is to describe general characteristics a cohort patients with early arthritis in Argentina.CONAART (Consorcio Argentino de Artritis Temprana--Argentine Consortium for Early Arthritis) an initiative seven rheumatology centres across Argentina. Patients were included if they had at least one or more swollen joints and <2 years disease duration. Social, demographic, familiar, hereditary, clinical laboratory data recollected. At first visit every year, X-rays hands...
Rheumatoid arthritis (RA) is a chronic, autoimmune disease characterized by joint destruction. Tofacitinib an oral Janus kinase inhibitor for the treatment of RA. This post hoc analysis assessed safety tofacitinib in Latin American (LA) patients with RA versus Rest World (RoW) population.Data were pooled from 14 clinical studies tofacitinib: six Phase 2, 3 and two long-term extension studies. Incidence rates (IRs; events/100 patient-years exposure) calculated events special interest combined...
Analyze disability determinants in a cohort of Argentine patients with rheumatoid arthritis (RA).Consecutive RA, according to ACR'87 criteria, were recruited from 6 rheumatology centers. Demographic and socioeconomic data, family history, comorbid diseases, extra-articular manifestations information about received treatments provided. Disease activity was assessed using Activity Score 28 (DAS 28) the Health Assessment Questionnaire (HAQ)-A used for functional capacity. Hand feet radiographs...
Rheumatoid nodulosis is an entity that describes a particular variant of polyarthritis associated with early manifestations palindromic rheumatism, radiologic subchondral bone cysts, and subcutaneous rheumatoid nodules. This study the clinical, radiologic, histologic, crystallographic, laboratory findings, as well outcome in group 16 patients were followed for period 1-12 years. Six these had aggressive course developed classic erosive polyarticular arthritis, while others continued having...
The blockade of inflammatory mediators produced by biological therapies is associated with an increased risk opportunistic infections, as for example Mycobacterium tuberculosis (MT). Given the endemic situation (TB) in some countries and immunosuppression/anergy patients chronic arthritis, we wonder whether it necessary to monitor MT infection after starting treatment. To evaluate frequency tuberculin skin test (TST) conversion its association active TB other disease variables.