A5103221315- Atherosclerosis and Cardiovascular Diseases
- Antibiotic Resistance in Bacteria
- Antimicrobial Resistance in Staphylococcus
- Cardiovascular Function and Risk Factors
- Cardiac Structural Anomalies and Repair
- Acute Myocardial Infarction Research
- Bacterial biofilms and quorum sensing
- Cardiac tumors and thrombi
- Infective Endocarditis Diagnosis and Management
- Lipoproteins and Cardiovascular Health
- Adipokines, Inflammation, and Metabolic Diseases
- Urinary Tract Infections Management
- Adipose Tissue and Metabolism
- Hormonal Regulation and Hypertension
- Cardiac, Anesthesia and Surgical Outcomes
- Coronary Interventions and Diagnostics
- Blood Pressure and Hypertension Studies
- Vitamin D Research Studies
- Cardiovascular Disease and Adiposity
- Cardiovascular Effects of Exercise
- Bacterial Identification and Susceptibility Testing
- Vibrio bacteria research studies
- Surgical site infection prevention
- Folate and B Vitamins Research
- Wound Healing and Treatments
Tehran University of Medical Sciences
2015-2025
AstraZeneca (United States)
2025
Shahid Sadoughi University of Medical Sciences and Health Services
2023
Addis Ababa University
2023
Tehran Heart Center
2011-2020
University of Tehran
2007-2015
University of Isfahan
1975
Sternal wound infection (SWI) is an uncommon but potentially life-threatening complication of cardiac surgery. Predisposing factors for SWI are multiple with varied frequencies in different studies. The purpose this study was to assess the incidence, risk factors, and mortality after coronary artery bypass grafting (CABG) at Tehran Heart Center.This prospectively evaluated 9201 patients who underwent CABG Center between January 2002 February 2006. Cases were confirmed based on criteria...
Probiotics are non-pathogenic microorganisms that can interact with the gastrointestinal microbiota. They have numerous beneficial health effects include enhancement of host immune response, antiallergic, antimicrobial, anti-cancer, and anti-inflammatory properties. capable restoring impaired microbiome a dysbiotic gut. be isolated from different environments. However, it is frequently suggested probiotics for human use should come sources. The objective this study was to isolate...
Abstract Background Oral mucositis (OM) is one of the main problems in almost all patients undergoing head and neck radiotherapy (RT). Owning to antioxidant anti-inflammatory properties curcumin, effect both oral topical formulations curcumin was assessed on radiation-induced OM (ROM) this study. Methods The safety efficacy mouthwash 0.1% (w/v) curcumin-nanocapsule were evaluated ameliorating severity pain/burning associated with during RT. current randomized, placebo-controlled trial...
Abstract Background Diabetes has been shown to be independent predictor of restenosis after percutaneous coronary intervention (PCI). The aim the present study was investigate whether a pre- and post-procedural glycaemic control in diabetic patients related major advance cardiovascular events (MACE) during follow up. Methods We evaluated 2884 consecutive including 2181 non-diabetic 703 diabetics who underwent stenting. mellitus defined as fasting blood sugar concentration ≥ 126 mg/dL, or use...
ABSTRACT Background and Aims In the current study, we aimed to identify association between major minor electrocardiographic abnormalities cardiovascular risk factors. Methods We used Tehran cohort study baseline data, an ongoing multidisciplinary, longitudinal designed disease factors in adult population of Tehran. The electrocardiograms (ECGs) 7630 Iranian adults aged 35 years above were analyzed. ECG categorized into or groups based on their clinical importance. Results obtained by...
Experimental screening for biopharmaceutical developability properties typically relies on resource-intensive, and time-consuming assays such as size exclusion chromatography (SEC). This study highlights the potential of in silico models to accelerate process by exploring sequence structure-based machine learning techniques. Specifically, we compared surrogate based pre-computed features extracted from predicted structure with sequence-based approaches using protein language (PLMs) like...
Although alcohol has been illegal in Iran for over four decades, its consumption persists. This study aims to determine the prevalence and determinants of Tehran, Middle East's third-largest city, using data from Tehran Cohort Study (TeCS). Our encompasses 8420 individuals recorded between March 2016 2019. We defined use as lifetime alcoholic beverages and/or products. calculated age- sex-weighted addition crude frequencies. also determined weighted both genders. Multivariable logistic...
Background: Cardiac implantable electronic device (CIED) infection is a significant complication associated with cardiac devices, resulting in considerable morbidity, mortality, and financial burden. In recent years, the rate of CIED implantation has increased, leading to corresponding rise infections. Objectives: This study investigates demographics, comorbidities, clinical presentations, microbiological findings, complications Methods: cross-sectional retrospective was conducted at Tehran...
Highly concentrated antibody solutions are necessary for developing subcutaneous injections but often exhibit high viscosities, posing challenges in antibody-drug development, manufacturing, and administration. Previous computational models were only limited to a few dozen data points training, bottleneck generalizability. In this study, we measured the viscosity of panel 229 monoclonal antibodies (mAbs) develop predictive concentration mAb screening. We developed DeepViscosity, consisting...
ANRIL is an important antisense noncoding RNA gene in the INK4 locus (9p21.3), a hot spot region associated with multiple disorders including coronary artery disease (CAD), type 2 diabetes mellitus (T2DM) and many different types of cancer. It has been shown that its expression dysregulated variety immune-mediated diseases. CAD major problem T2DM patients cause almost 60% deaths these worldwide. The aim present study was to compare level between without CAD.In this case-control study, we...
There is growing clinical interest in liver transaminases as novel biomarkers of cardiovascular risk. We investigated the possible association serum transaminase activity with presence and angiographic severity premature coronary artery disease (CAD). A cross-sectional study was conducted on 187 younger patients (females <55 years males <45 years) who underwent angiography had aspartate aminotransferase (AST), alanine (ALT), high-sensitivity C-reactive protein (hsCRP) measured....
Catheter-related blood circulation infection is the most dangerous and serious side-effects of vascular catheters, which leads to enhancement costs, mortality, hospital stay duration, especially in Intensive Care Unit. Regarding this, aim current study was identify prevalence catheter-induced candidemia Tehran Heart Center, a heart Tehran, Iran.This conducted on patients admitted Center for minimum 7 days during 18 months. To detect fungal elements, culture catheter were performed receiving...
The spreading of opium use poses new health related concerns. In some areas Asia its is believed to protect from cardiovascular disorders, such as coronary artery disease (CAD). However, whether has an association with CAD unclear. We aimed investigate the between non-medical and CAD. set up a case-control analysis, i.e., Milano-Iran (MIran) study by enrolling consecutive young patients who underwent angiography at Tehran Heart Center, 2004 2011. Incident cases were contrasted controls for...
Despite global efforts to tackle resistance in extended-spectrum beta-lactamase (ESBL)-producing isolates via old antibiotics, there are limited data on the efficacy of fosfomycin-an oral antibiotic-against Enterobacteriaceae Middle East. The purpose this study was evaluate vitro activity fosfomycin against urinary ESBL-producing Enterobacteriaceae. Between 2004 and 2015, 363 were recovered from high-risk patients suffering cardiac disorders subjected polymerase chain reaction using specific...