- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Liver Disease Diagnosis and Treatment
- Diet, Metabolism, and Disease
- COVID-19 and healthcare impacts
- SARS-CoV-2 and COVID-19 Research
- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Transplantation: Methods and Outcomes
- Cardiac Imaging and Diagnostics
- Liver Disease and Transplantation
- Diabetes and associated disorders
- Cardiac Valve Diseases and Treatments
- COVID-19 diagnosis using AI
- COVID-19 and Mental Health
- Mechanical Circulatory Support Devices
- Renal Transplantation Outcomes and Treatments
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Antiplatelet Therapy and Cardiovascular Diseases
- Pharmacology and Obesity Treatment
- Vascular Procedures and Complications
- Coronary Artery Anomalies
- Diagnosis and Treatment of Venous Diseases
- Cardiovascular and Diving-Related Complications
- Urinary Bladder and Prostate Research
Sina Hospital
2011-2024
Tehran University of Medical Sciences
2011-2024
Sina (China)
2014
In this study, we aimed to assess the association between development of cardiac injury and short-term mortality as well poor in-hospital outcomes in hospitalized patients with COVID-19. prospective, single-center enrolled laboratory-confirmed COVID-19 highly suspicious compatible chest computed tomography features. Cardiac was defined a rise serum high sensitivity Troponin-I level above 99th percentile (men: > 26 ng/mL, women: 11 ng/mL). A total 386 were included. present among 115 (29.8%)...
Abstract BACKGROUND There is an ongoing controversy about harms and benefits of angiotensin-converting enzyme inhibitors (ACEIs) angiotensin II receptor blockers (ARBs) in hypertensive patients with coronavirus disease 2019 (COVID-19). Given the unresolved debate, we investigated association ARBs in-hospital outcomes these patients. METHODS In this retrospective observational study, studied COVID-19 who referred to Sina Hospital Tehran, Iran, from 20 February 29 May 2020. Patients either...
Abstract Background and Aims Primary percutaneous coronary intervention (PCI) is the treatment of choice in ST‐elevation myocardial infarction (STEMI) patients. This study aims to evaluate predictors in‐hospital long‐term mortality among patients with STEMI undergoing primary PCI. Methods In this registry‐based study, we retrospectively analyzed PCI enrolled angioplasty registry Sina Hospital. Independent were determined using multivariate logistic regression Cox analyses, respectively....
There is growing clinical interest in liver transaminases as novel biomarkers of cardiovascular risk. We investigated the possible association serum transaminase activity with presence and angiographic severity premature coronary artery disease (CAD). A cross-sectional study was conducted on 187 younger patients (females <55 years males <45 years) who underwent angiography had aspartate aminotransferase (AST), alanine (ALT), high-sensitivity C-reactive protein (hsCRP) measured....
Abstract Background A few studies compared the characteristics and outcomes of COVID-19 patients during first second surges disease. We aimed to describe clinical features across first, second, third disease in Tehran, Iran. Method conducted a retrospective cohort study with admitted Sina hospital Iran, three from February 16 October 28, 2020. Result Surge 1 were younger more prevalence hypertension. They also presented significantly higher oxygen saturation, systolic blood pressure,...
The prognostic factors of long-term outcomes in hospitalized patients with diabetes mellitus and COVID-19 are lacking. In this retrospective cohort study, we evaluated aged ≥ 18-years-old the diagnosis who were between Feb 20 Oct 29, 2020, Sina Hospital, Tehran, Iran. 1323 entered final analysis, whom 393 (29.7%) had diabetes. We followed up for incurring in-hospital death, severe COVID-19, complications, 7-month all-cause mortality. By doing univariate variables unadjusted P-value < 0.1...
Aim: Rapid and growing rise in obesity diabetes mellitus, as serious human health-threatening issues, is alarming. The aim of the present study was assessing accuracy several indices to predict hyperglycemia overweight obese Iranian populations determining value such comparison conventional parameters. We also evaluated new latent combined scores this matter. Patients Methods: Overall, there were 2088 patients recruited from weight loss clinic Sina Hospital, an educational hospital Tehran...
Heart transplantation has been considered the gold-standard treatment for patients with end-stage heart failure. This study assessed survival outcomes of marginal donor hearts compared ideal in Iran.This retrospective is based on follow-up data donors and recipients Sina Hospital Organ Procurement Unit. Among 93 participants, 75 were categorized as (group A) 18 B). Group C included who received a standard organ, group D one. To analyze differences patient characteristics among groups,...
BACKGROUND: To evaluate the effects of Helicobacter pylori (HP) eradication on liver function tests (LFT) and fat content (LFC) in non-diabetic non-alcoholic steatohepatitis (NASH). METHODS: This randomized clinical trial included dyspeptic HP infected NASH participants. The intervention arm received treatment, while control did not get any treatment. In meantime, standard management was performed both arms. Mean alterations LFT were primary outcome secondary outcomes mean changes LFC serum...
In the last days of 2019, a new coronavirus emerged in Wuhan, China, and less than three months its disease, now called COVID-19, was announced global pandemic by WHO. COVID-19 usually causes respiratory symptoms can lead to more severe conditions like ARDS. HLA has crucial role regulating immune system; thus, different allele types be protective or risk factor for some diseases, so we aimed find such associations determine whether alleles predict susceptibility resistibility finally...
Although the effectiveness of some combined anthropometric and metabolic scores were evaluated in hypertension prediction, none them had addressed their accuracy association with overweight/obese populations. This study examined several parameters this regard compared novel indices to ancient ones.Through a cross-sectional study, 5115 patients have been at weight loss clinic. Data on demographic information, indices, biochemical measurements assembled into checklist. Multivariable regression...
Background: Since the outbreak of coronavirus 2019 (COVID-19), identifying risk factors associated with in-hospital mortality has been a global priority. In this study, purpose was to evaluate clinical, laboratory, and radiological characteristics hospitalized patients COVID-19 develop predictive model scoring system for mortality. Methods: retrospective cohort 611 adult COVID-19, admitted Sina hospital were enrolled followed up. Results: Out total number patients, 104 (17%) deceased during...
Hemodialysis catheter fracture with distal embolization is a rare complication. The natural process of retained asymptomatic hemodialysis unclear. This report an iatrogenic the tip in adult patient who was successfully retrieved using image-guided endovascular technique. In event embolization, percutaneous retrieval treatment choice.
Background: Limited data exist on the clinical outcomes of patients with coronavirus disease 2019 (COVID-19) presenting ST-segment-elevation myocardial infarction (STEMI). Methods: This multicenter study, conducted in 6 centers Iran, aimed to compare baseline and procedural between a case group, comprising STEMI COVID-19, control before COVID-19 pandemic, determine in-hospital infarct-related artery thrombus grades major adverse cardio-cerebrovascular events (MACCEs), defined as composite...
1General Cardiology Department, Tehran Heart Centre, University of Medical Sciences, Tehran, Iran 2Cardiovascular Research 3Cardiothoracic Imaging Beth Israel Deaconess Harvard School, Boston, MA, United States 4General Sina Hospital,
Nonalcoholic fatty liver disease and cardiovascular concerns: The time for hepatologist cardiologist close collaboration
Fingolimod was the first oral therapy approved for treating relapsing-remitting multiple sclerosis (RRMS) in 2010. This open-label study evaluated safety and efficacy of fingolideR, 0.5 mg Iranian MS patients during one-year follow-up.A multicenter, open-label, longitudinal designed to evaluate over a follow-up period across 11 centers. The were visited by their neurologists every two months possible adverse events clinical disease activity considered recording Kurtzke's Expanded Disability...
Cardiovascular diseases, especially ST-elevation myocardial infarction (STEMI), are among the major health concerns in Iran. Although primary percutaneous coronary intervention (pPCI) is performed as treatment of choice Iranian hospitals, there limited data on its efficacy, safety, procedural variations, and clinical outcomes after implementation new Protocol-247, which transfers patients with STEMI directly to pPCI-capable hospitals. The Primary Angioplasty Registry Sina (PARS) an ongoing...
Introduction: Owing to the imposed burden of coronavirus disease 2019 (COVID-19),the need for stratifying prognosis patients has never been timelier. Hence, we aimed ascertain value CHADS2, CHA2DS2-VASc, and CHA2DS2-VASc-M (one point male instead female) scores predict unfavorable outcomes in COVID-19 patients. Methods: We enrolled consecutive above 18 years age with confirmed COVID-19,who were admitted between February 16 November 1, 2020. The primary endpoint this study was three-month...
Introduction: Pseudoaneurysm may occur as a rare complication of myocardial infarction (MI) when hemorrhagic process is covered by adherence the visceral or parietal pericardium both, preventing formation cardiac tamponade. prone to rupture because they are not easy diagnose. Case presentation: Here, we report three cases left ventricular pseudo-aneurysm (LVP) that all were related MI. Two patients managed conservatively, one them was lost follow-up, and other expired month later. One...