A5082598559- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- COVID-19 and healthcare impacts
- SARS-CoV-2 and COVID-19 Research
- Influenza Virus Research Studies
- Diabetes and associated disorders
- Respiratory Support and Mechanisms
- Trace Elements in Health
- Vitamin D Research Studies
- Infectious Encephalopathies and Encephalitis
- Pancreatitis Pathology and Treatment
- Antifungal resistance and susceptibility
- Epilepsy research and treatment
- COVID-19 Impact on Reproduction
- Magnesium in Health and Disease
- Fungal Infections and Studies
- Nutrition and Health in Aging
- Vaccine Coverage and Hesitancy
- Viral gastroenteritis research and epidemiology
- Urinary Tract Infections Management
- Surgical site infection prevention
- Brucella: diagnosis, epidemiology, treatment
- Vitamin C and Antioxidants Research
- HIV, Drug Use, Sexual Risk
- HIV/AIDS Research and Interventions
Tehran University of Medical Sciences
2020-2024
Sina Hospital
2020-2024
University of Tehran
2021
Imam Khomeini Hospital
2013
Background To investigate the association between serum 25-hydroxyvitamin D levels and its effect on adverse clinical outcomes, parameters of immune function mortality due to a SARS-CoV-2 infection. Study design The hospital data 235 patients infected with COVID-19 were analyzed. Results Based CDC criteria, among our study patients, 74% had severe infection 32.8% vitamin sufficient. After adjusting for confounding factors, there was significant sufficiency reduction in severity, inpatient...
Currently no effective antiviral therapy has been found to treat COVID-19. The aim of this trial was assess if the addition sofosbuvir and daclatasvir improved clinical outcomes in patients with moderate or severe COVID-19.This an open-label, multicentre, randomized controlled adults COVID-19 admitted four university hospitals Iran. Patients were into a treatment arm receiving plus standard care, control care alone. primary endpoint recovery within 14 days treatment. study is registered...
In this study, we aimed to assess the association between development of cardiac injury and short-term mortality as well poor in-hospital outcomes in hospitalized patients with COVID-19. prospective, single-center enrolled laboratory-confirmed COVID-19 highly suspicious compatible chest computed tomography features. Cardiac was defined a rise serum high sensitivity Troponin-I level above 99th percentile (men: > 26 ng/mL, women: 11 ng/mL). A total 386 were included. present among 115 (29.8%)...
Without an adequate immune response, SARS-CoV2 virus can simply spread throughout the body of host. Two well-known immunonutrients are selenium (Se) and zinc (Zn). Se Zn deficiency might lead to inflammation, oxidative stress, viral entry into cells by decreasing ACE-2 expression; three factors that proposed be involved in COVID-19 pathogenesis. Thus, current study we aimed at evaluating correlation between serum status severity. Eighty-four patients were enrolled this observational study....
COVID-19 has become a pandemic since December 2019, causing millions of deaths worldwide. It wide spectrum severity, ranging from mild infection to severe illness requiring mechanical ventilation. In the middle pandemic, when medical resources (including ventilators) are scarce, there should be scoring system provide clinicians with information needed for clinical decision-making and resource allocation.This study aimed develop based on data obtained admission, predict need ventilation in...
Background: We aimed to assess the gastrointestinal (GI) manifestations of patients with severe acute respiratory syndrome coronavirus 2 infection and determine factors predicting disease prognosis severity among GI symptoms. Methods: In this retrospective study, we evaluated laboratory confirmed (by real-time polymerase chain reaction) inpatient cases coronavirus-associated 2019 (COVID-19), referred Sina hospital, a tertiary educational hospital Tehran University Medical Sciences, from...
<b><i>Introduction:</i></b> Kidney involvement, ranging from mild hematuria and proteinuria to acute kidney injury (AKI) in patients with coronavirus disease-2019 (COVID-19), is a recent finding various incidence rates reported among hospitalized COVID-19. Given the AKI their associated risk factors, lack of recovery majority COVID-19, limited data regarding COVID-19 Iran, we aim investigate potential factors for development its...
Background: Invasive fungal infections (IFIs) are a significant cause of mortality and morbidity in patients with hematological malignancies. Given the considerable prevalence consequences IFIs, hence revealing exact infections, their rate, associated risk factors, complications could contribute to reducing both financial life costs, choosing targeted antifungal treatment, avoiding unnecessary toxic treatments individuals who not suffering from mycoses.
 Materials Methods: This...
The aim of the study was to investigate association between serum 25-hydroxyvitamin D levels and its effect on adverse clinical outcomes, parameters immune function mortality due a SARS-CoV-2 infection. Method: Hospital medical records were analyzed from inpatient database Sina COVID-19 Registry (SHCo-19R). data include demographics, laboratory measurements computerized tomography results. Vitamin sufficiency defined [25(OH)D] level at least 30ng/mL.Results: hospital 235 patients infected...
<b><i>Objective:</i></b> To describe a case with Brucella-associated meningoencephalitis. In addition, we report drug-induced hepatotoxicity due to acyclovir. <b><i>Clinical Presentation and Intervention:</i></b> A young woman was admitted fever psychosis neuroimaging findings indicative of Serology positive for Brucella. She treated doxycycline, rifampin, trimethoprim-sulfamethoxazole. <b><i>Conclusion:</i></b> This...
Amongst the neurologic complications of COVID-19 disease, very few reports have shown presence virus in cerebrospinal fluid (CSF). Seizure and rarely status epilepticus can be associated with disease. Here we present a 73-year-old male prior history stroke who has never experienced seizure before. He had no systemic presentation The presenting symptoms were two consecutive generalized tonic-clonic seizures that after initial resolution turned into nonconvulsive despite antiepileptic...
Psoas tuberculosis abscess is very rarely detected primarily without an adjacent vertebral cold abscess. Early diagnosis prevents unnecessary operations and life-threatening complications.
The prognostic factors of long-term outcomes in hospitalized patients with diabetes mellitus and COVID-19 are lacking. In this retrospective cohort study, we evaluated aged ≥ 18-years-old the diagnosis who were between Feb 20 Oct 29, 2020, Sina Hospital, Tehran, Iran. 1323 entered final analysis, whom 393 (29.7%) had diabetes. We followed up for incurring in-hospital death, severe COVID-19, complications, 7-month all-cause mortality. By doing univariate variables unadjusted P-value < 0.1...
Seasonal influenza is an annual common occurrence in cold seasons; but the COVID-19 pandemic also currently ongoing. These two diseases can't be distinguished from their symptoms alone; therefore, importance of preventing by vaccination more than ever. Due to high exposure hospital personnel, widespread these high-risk groups seems a necessity. This Study conducted determine coverage personnel four tertiary referral collegiate hospitals 2019 and further investigate individual obstacles for...
Background: Since the outbreak of coronavirus 2019 (COVID-19), identifying risk factors associated with in-hospital mortality has been a global priority. In this study, purpose was to evaluate clinical, laboratory, and radiological characteristics hospitalized patients COVID-19 develop predictive model scoring system for mortality. Methods: retrospective cohort 611 adult COVID-19, admitted Sina hospital were enrolled followed up. Results: Out total number patients, 104 (17%) deceased during...
Introduction: Owing to the imposed burden of coronavirus disease 2019 (COVID-19),the need for stratifying prognosis patients has never been timelier. Hence, we aimed ascertain value CHADS2, CHA2DS2-VASc, and CHA2DS2-VASc-M (one point male instead female) scores predict unfavorable outcomes in COVID-19 patients. Methods: We enrolled consecutive above 18 years age with confirmed COVID-19,who were admitted between February 16 November 1, 2020. The primary endpoint this study was three-month...
Background: Since the initiation of new coronavirus (COVID-19) in February 2020 Wuhan, Health Care System (HCS) has tolerated a lot morbidities and mortalities all around world. While COVID -19 is spreading out whole world, HCS carries almost burden as first line. However, countries like Iran suffer from lack infected Workers (HCW) population data statistics, especially major hospitals for COVID-19 referrals.
 Methods: In this single-center cross sectional study, we studied healthcare...
Remdesivir, an antiviral medication, became early promising therapeutic candidate for coronavirus disease 2019 (COVID-19) due to its ability inhibit the virus in vitro. Current evidence about remdesivir treatment has been very controversial, so we aim evaluate improve our knowledge COVID-19 management and long-term effects. In this retrospective cohort study using registered data derived from Sina Hospital Registry with a 9-month follow-up, enrolled patients receiving then matched "control...
AMA Ebrahimi H, Moafi M, Moaveni A, et al. Cognitive impairment in COVID-19 patients and its relation to laboratory data. Neuropsychiatria i Neuropsychologia/Neuropsychiatry Neuropsychology. 2023;18(1):85-91. doi:10.5114/nan.2023.129076. APA Ebrahimi, H., Moafi, M., Moaveni, A., Pour-Rashidi, & Azimi, H. (2023). Neuropsychology, 18(1), 85-91. https://doi.org/10.5114/nan.2023.129076 Chicago Hannan, Maral Amir Kian Mohammad Javad Ahmad Hesam Azar Hadadi 2023. "Cognitive data". Neuropsychology...
Comparing Therapeutic versus Prophylactic Enoxaparin Therapy in Severe COVID-19 Patients: A Randomized Clinical Trial