- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Liver Disease Diagnosis and Treatment
- Cardiovascular Function and Risk Factors
- Acute Myocardial Infarction Research
- Heart Failure Treatment and Management
- Cardiac Imaging and Diagnostics
- Cardiac Health and Mental Health
- SARS-CoV-2 and COVID-19 Research
- COVID-19 and Mental Health
- Coronary Interventions and Diagnostics
- Cardiac electrophysiology and arrhythmias
- COVID-19 and healthcare impacts
- Diabetes and associated disorders
- Cardiac Arrhythmias and Treatments
- Diet, Metabolism, and Disease
- COVID-19 diagnosis using AI
- Diabetes Management and Research
- Blood Pressure and Hypertension Studies
- Cardiac Structural Anomalies and Repair
- Cardiovascular Health and Disease Prevention
- Cardiomyopathy and Myosin Studies
- Renal Transplantation Outcomes and Treatments
- Obesity, Physical Activity, Diet
Tehran University of Medical Sciences
2015-2025
Sina Hospital
2011-2024
Tehran Heart Center
2024
The University of Texas Health Science Center at Houston
2024
Shaheed Rajaei Cardiovascular Medical and Research Center
2022-2023
Iran University of Medical Sciences
2022-2023
Cardiovascular Diseases Research Institute
2023
Addis Ababa University
2023
Janbazan Medical and Engineering Research Center
2014
Hasheminejad Kidney Center
2013
Purpose: To translate long form, interview-administered International Physical Activity Questionnaire (IPAQ) from English to Persian and evaluate its validity, reliability reproducibility. Methods: A forward-backward translation procedure was followed develop the version of IPAQ. total 218 respondents (53.7% women, aged 2276 yr) completed in Tehran, Iran. examine testretest reliability, 48 healthy volunteers IPAQ twice during a 7-day period.. The PA indicators derived were assessed for...
As COVID-19 hounds the world, common cause of finding a swift solution to manage pandemic has brought together researchers, institutions, governments, and society at large. The Internet Things (IoT), artificial intelligence (AI)-including machine learning (ML) Big Data analytics-as well as Robotics Blockchain, are four decisive areas technological innovation that have been ingenuity harnessed fight this future ones. While these highly interrelated smart connected health technologies cannot...
We have recently determined the optimal cut-off of homeostatic model assessment insulin resistance for diagnosis (IR) and metabolic syndrome (MetS) in non-diabetic residents Tehran, capital Iran. The aim present study is to establish at national level Iranian population with without diabetes.Data third National Surveillance Risk Factors Non-Communicable Diseases, available 3,071 adult individuals aging 25-64 years were analyzed. MetS was defined according Adult Treatment Panel III (ATPIII)...
In this study, we aimed to assess the association between development of cardiac injury and short-term mortality as well poor in-hospital outcomes in hospitalized patients with COVID-19. prospective, single-center enrolled laboratory-confirmed COVID-19 highly suspicious compatible chest computed tomography features. Cardiac was defined a rise serum high sensitivity Troponin-I level above 99th percentile (men: > 26 ng/mL, women: 11 ng/mL). A total 386 were included. present among 115 (29.8%)...
Without an adequate immune response, SARS-CoV2 virus can simply spread throughout the body of host. Two well-known immunonutrients are selenium (Se) and zinc (Zn). Se Zn deficiency might lead to inflammation, oxidative stress, viral entry into cells by decreasing ACE-2 expression; three factors that proposed be involved in COVID-19 pathogenesis. Thus, current study we aimed at evaluating correlation between serum status severity. Eighty-four patients were enrolled this observational study....
Abstract Background Unlike diabetes, the effect of prediabetes on outcomes in patients with acute coronary syndrome (ACS) who underwent percutaneous intervention (PCI) is not much investigated. We investigated association between fasting glycemic status and major adverse cardiovascular cerebrovascular events (MACCE) ACS undergoing PCI had mid to long‐term follow‐up after stenting. Methods Registry‐based retrospective cohort study included at Tehran Heart Center from 2015 2021 a median 378...
ACADEMIC EMERGENCY MEDICINE 2011; 18:800–806 © 2011 by the Society for Academic Emergency Medicine Abstract Objectives: The authors performed a prospective, double-blinded, randomized trial with emergency department (ED) patients requiring procedural sedation and analgesia (PSA) repair of deep traumatic lacerations reduction bone fractures, to compare ketamine/propofol (ketofol) combination midazolam/fentanyl (MF) combination. Methods: Sixty-two scheduled PSA who presented between January...
Electrocardiographic (ECG) changes are reported frequently after acute strokes. It seems that cardiovascular effects of strokes modulated by concomitant or pre-existent cardiac diseases, and also related to the type cerebrovascular disease its localization. We aimed determine pattern ECG associated with pathophysiologic categories stroke among patients with/without if specific location lesion.The electrocardiographic records 361 were studied assess relative frequencies abnormalities...
Abstract BACKGROUND There is an ongoing controversy about harms and benefits of angiotensin-converting enzyme inhibitors (ACEIs) angiotensin II receptor blockers (ARBs) in hypertensive patients with coronavirus disease 2019 (COVID-19). Given the unresolved debate, we investigated association ARBs in-hospital outcomes these patients. METHODS In this retrospective observational study, studied COVID-19 who referred to Sina Hospital Tehran, Iran, from 20 February 29 May 2020. Patients either...
Background Epidemiologic research suggests that gut microbiota alteration (dysbiosis) may play a role in the pathogenesis of metabolic syndrome (MetS). Dysbiosis can influence Trimethylamine N-oxide (TMAO) microbiota-derived metabolite, as well kynurenine pathways (KP), which are known new marker for an early predictor chronic diseases. Hence, current study aimed to investigate association between KYN and TMAO with MetS its components. Methods This case-control was conducted on 250 adults...
Percutaneous coronary intervention (PCI) is considered the procedure of choice for patients with acute syndrome (ACS), as it significantly improves cardiovascular outcomes. However, considerable uncertainty persists regarding potential sex differences in PCI outcomes, due to conflicting results previous studies. This meta-analysis aims evaluate sex-related adverse outcomes after among ACS patients. The primary outcome was major events (MACE) and its components. Outcomes were examined various...
Abstract Background Integration of artificial intelligence enhances precision, yielding dependable evaluations left ventricular volumes and ejection fraction despite image quality variations. Dilated cardiomyopathy patients have low with dilated volumes, which affect the diagnostic accuracy automated 3D echocardiography. Establishing fully 3DE quantification software, simplify accelerate measurement chamber fraction. Objective In this manuscript, we present a cross-sectional study to assess...
Acute myocardial infarction (AMI) remains a leading global cause of mortality. This study explores predictors in-hospital mortality among AMI patients using advanced machine learning (ML) techniques. Data from 7422 treated with percutaneous coronary intervention (PCI) at Tehran Heart Center (2015-2021) were analyzed. Fifty-eight clinical, demographic, and laboratory variables evaluated. Seven ML algorithms, including Random Forest (RF), logistic regression LASSO, XGBoost, implemented. The...
Background There are some data showing that repurposed drugs used for the Coronavirus disease-19 (COVID-19) have potential to increase risk of QTc prolongation and torsade de pointes (TdP), these arrhythmic side effects not been adequately addressed in COVID-19 patients treated with medications. Methods This is prospective study 2403 hospitalised at 13 hospitals within epicentres Iran. These were chloroquine, hydroxychloroquine, lopinavir/ritonavir, atazanavir/ritonavir, oseltamivir,...
The role of angiotensin-converting enzyme inhibitors (ACEis) and angiotensin receptor blockers (ARBs) has been addressed in some studies related to the current coronavirus disease-2019 (COVID-19) pandemic with possible higher severity mortality patients hypertension. A triple-blind randomized controlled trial was designed evaluate effects these medications on COVID-19 progression.Patients were enrolled this between April September 2020. They 2 groups. former dosage ACEis/ARBs continued one...
Abstract Background and Aims Primary percutaneous coronary intervention (PCI) is the treatment of choice in ST‐elevation myocardial infarction (STEMI) patients. This study aims to evaluate predictors in‐hospital long‐term mortality among patients with STEMI undergoing primary PCI. Methods In this registry‐based study, we retrospectively analyzed PCI enrolled angioplasty registry Sina Hospital. Independent were determined using multivariate logistic regression Cox analyses, respectively....
Abstract Introduction Tobacco use is a major health concern worldwide, especially in low/middle-income countries. We aimed to assess the prevalence of cigarette smoking, waterpipe, and pipe Tehran, Iran. Methods used data from 8272 participants Tehran Cohort Study recruitment phase. was defined as positive answer using cigarettes, waterpipes, or pipes. Participants who did not report tobacco during interview but had previous smoking history were categorized former users. Age- sex-weighted...
Spasm of the internal anal sphincter plays a role in haemorrhoidal disease and may be source pain after haemorrhoid surgery. In this study, we investigated effect topical diltiazem (DTZ) on postoperative following Milligan-Morgan haemorrhoidectomy.After haemorrhoidectomy, 33 patients were randomly assigned to receive DTZ ointment (2%; n = 16) or placebo (n 17). Ointments applied perianal region three times daily for 7 days. A Visual Analogue Scale was used assess pain. The primary end-point...