- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Antibiotic Use and Resistance
- Long-Term Effects of COVID-19
- Antibiotic Resistance in Bacteria
- Pneumocystis jirovecii pneumonia detection and treatment
- Antimicrobial Resistance in Staphylococcus
- Vitamin D Research Studies
- Diagnosis and treatment of tuberculosis
- Nosocomial Infections in ICU
- Tuberculosis Research and Epidemiology
- Infectious Diseases and Tuberculosis
- Bacterial Identification and Susceptibility Testing
- HIV/AIDS Research and Interventions
- Urinary Tract Infections Management
- Vaccine Coverage and Hesitancy
- Infection Control in Healthcare
- Pharmacological Effects and Toxicity Studies
- Inflammasome and immune disorders
- Influenza Virus Research Studies
- Viral Infections and Outbreaks Research
- Muscle and Compartmental Disorders
- Animal Virus Infections Studies
- Viral-associated cancers and disorders
- Brucella: diagnosis, epidemiology, treatment
Taif University
2025
Tehran University of Medical Sciences
2014-2024
Sina Hospital
2013-2023
University of Tehran
2006-2021
Shariati Hospital
2021
Iranian Institute for Health Sciences Research
2018
Imam Khomeini Hospital
2010-2014
Office of Infectious Diseases
2009
Background To investigate the association between serum 25-hydroxyvitamin D levels and its effect on adverse clinical outcomes, parameters of immune function mortality due to a SARS-CoV-2 infection. Study design The hospital data 235 patients infected with COVID-19 were analyzed. Results Based CDC criteria, among our study patients, 74% had severe infection 32.8% vitamin sufficient. After adjusting for confounding factors, there was significant sufficiency reduction in severity, inpatient...
An 80-year-old man with multiple comorbidities presented to the emergency department tachypnea, tachycardia, fever, and critically low O2 saturation definitive chest computerized tomography scan findings in favor of COVID-19 positive PCR results 48 hours. He received antiviral treatment plus recombinant human erythropoietin (rhEPO) due his severe anemia. After 7 days treatment, he was discharged miraculous improvement symptoms hemoglobin level. We concluded that rhEPO could attenuate...
Hypervirulent Klebsiella pneumoniae (hvKp) has emerged as a pathogen of global concern. In this study, both phenotypic and genotypic tests were used to detect hvKp. Antimicrobial resistance profiles clonal relatedness clinical isolates also determined. We found that 34.2% (163/477) the tellurite resistant, among them 102 hvKp detected with iucA or iutA peg-344 molecular markers. The bla
Several studies reported the immediate positive effect of core stability exercises on postural balance in different populations. However, other documented no significant performance. It remains unclear whether a single session can improve soccer players with groin pain (GP). This study aimed to investigate acute this parameter these players. A total 15 male GP carried out lasting 40 min. Static (force platform) and dynamic (Y-Balance test) outcomes were assessed 4 times: just before (T0),...
Diabetes mellitus (along with its complications) has become a global problem. Diabetic foot infection, among the most common complications, is responsible for 40 to 50% of amputations. Antibiotic-resistant microorganisms, however, have compromised empiric therapy in infected patients.The current study aimed determine microorganisms involved diabetic infection order minimize failure antibiotic and risk developing complications.All patients admitted infectious diseases, surgery endocrinology...
The SARS-CoV-2 virus has been rapidly spreading globally since December 2019, triggering a pandemic, soon after its emergence. While Iran was among the first countries confronted with rapid spread of in February 2020, no real-time whole-genome tracking early phase outbreak performed country. To address this issue, we provided 50 sequences viral isolates ascertained from different geographical locations during March–July 2020. corresponding analysis on origins, transmission dynamics and...
Introduction : Acinetobacter species in clinical isolates cause severe infections including meningitis, bloodstream infection, ventilator-associated pneumonia, and surgical site infections. Objectives In the present study, we evaluated drug resistance using both European Committee on Antimicrobial Susceptibility Testing (EUCAST) Clinical Laboratory Standards Institute (CLSI) antimicrobial susceptibility test methods. Materials Methods: specimens of 128 patients who were admitted three...
Background: We aimed to assess the gastrointestinal (GI) manifestations of patients with severe acute respiratory syndrome coronavirus 2 infection and determine factors predicting disease prognosis severity among GI symptoms. Methods: In this retrospective study, we evaluated laboratory confirmed (by real-time polymerase chain reaction) inpatient cases coronavirus-associated 2019 (COVID-19), referred Sina hospital, a tertiary educational hospital Tehran University Medical Sciences, from...
Background. Rectus sheath hematoma is a rare self-limited presentation that has become concern in hospitalized COVID-19 patients receiving anticoagulant therapies. Method. A retrospective multicentric study was conducted referral hospitals affiliated with the Tehran University of Medical Science, Tehran, Iran, between June and August 2021. Patients confirmed diagnosis were complicated rectus during hospitalization included. Median (lower quartile to upper quartile) used report distribution...
Introduction: Since December 2019, an outbreak of Covid-19 has caused growing concern in multiple countries. Researchers around the world are working to find a treatment or vaccine for and different approaches have been tested this regard. Objective: This study was designed conducted assess possible efficacy Interferon beta-1a as safe efficient candidate treatment. Methods: is investigator-initiated, open-label, single-arm clinical trial. Twenty patients with suspected Covid-19, who were...
Genitourinary tuberculosis (GT) includes 8–15% of extrapulmonary (TB), which is more frequent in men. Epididymides, seminal vesicles, prostate and testis are the most common sites GT. Although testicular TB uncommon, we report 2 patients with unilateral TB. The main treatment urogenital anti-tuberculosis pharmacotherapy, sometimes combined surgery.
Surveillance of health care-associated infections (HCAIs) is an integral part infection control programmes, especially in intensive care units (ICUs). Device-associated (DAIs) are a major threat to patient safety.To measure DAI rates ICUs.Central line-associated bloodstream (CLABSI), ventilator-associated pneumonia (VAP), and catheter- associated urinary tract (CAUTI) were assessed the ICUs 4 tertiary-care teaching hospitals Tehran, Islamic Republic Iran.The incidence rate CLABSI, VAP CAUTI...
Objectives: We assessed the effect of selenium and zinc supplementation on CD4 cell count risk developing opportunistic infections.Methods: In a double blind clinical trial, 146 HIV(+) patients receiving combination antiretroviral therapy with CD4(+) >200/cubic millimeter were screened for comorbidities infections, randomized to receive daily (200 µg), (50 mg) or placebo 6 months, before 3-month follow-up period. counts measured in 3th, 6th 9th months. The serum month. incidence infection...
The aim of the study was to investigate association between serum 25-hydroxyvitamin D levels and its effect on adverse clinical outcomes, parameters immune function mortality due a SARS-CoV-2 infection. Method: Hospital medical records were analyzed from inpatient database Sina COVID-19 Registry (SHCo-19R). data include demographics, laboratory measurements computerized tomography results. Vitamin sufficiency defined [25(OH)D] level at least 30ng/mL.Results: hospital 235 patients infected...
To estimate and outline the frequency etiology of lymphadenopathy in HIV/AIDS patients. This study was conducted on 178 consecutive patient files for etiologies (categorized into three sub-groups: definite, probable possible) associated factors local generalized lymphadenopathy. Seventy-two (40.45%) patients including 63 male (87.5%) developed HIV lymphadenopathy(+) most commonly transmitted intravenously (n=49). Generalized localized respectively occurred 27 (37.50%) 45 (62.50%) patients,...
The purpose of this paper is to identify the main reasons for discharge against medical advice (DAMA) in emergency department (ED) a teaching hospital Tehran, Iran.This cross-sectional study was conducted on all patients who left ED referral (AMA) 2008. A questionnaire filled out each patient determine behind leaving AMA.In total, 12.8 percent AMA. Dissatisfaction with being observed ED, having feeling recovery and personnel encouraging leave were AMA.Like many other centers, results showed...
The purpose of this study is to compare the efficacy prophylactic antibiotic for prevention meningitis in acute traumatic pneumocephalus patients.In prospective, randomized controlled clinical trial, 200 selected head injury patients with are randomly assigned receive intravenous antibiotics (2 grams Ceftriaxone twice a day), oral (Azithromycin) or placebo at least 7 days after trauma. will be followed one month posttrauma.The authors hope that helps clarifying effectiveness and indications...
AbstractBackground- Brucellosis is one of the most frequent infectious diseases in many regions Iran. The purpose this study was to evaluate different clinical, laboratory and therapeutic aspects disease.Method- This retrospective descriptive performed on patients referred two teaching hospitals Tehran/Iran with brucellosis diagnosis during years 1998 - 2005. Patients" signs symptoms, findings clinical responses were evaluated period.Results- More than half 415 enrolled female. duration...