A5057978524- Viral gastroenteritis research and epidemiology
- Hepatitis C virus research
- Hepatitis B Virus Studies
- SARS-CoV-2 and COVID-19 Research
- Animal Virus Infections Studies
- Viral-associated cancers and disorders
- Liver Disease Diagnosis and Treatment
- Viral Infections and Immunology Research
- Cytomegalovirus and herpesvirus research
- COVID-19 Clinical Research Studies
- Herpesvirus Infections and Treatments
- Cancer-related molecular mechanisms research
- Systemic Lupus Erythematosus Research
- Virus-based gene therapy research
- Parvovirus B19 Infection Studies
- MicroRNA in disease regulation
- Hepatitis Viruses Studies and Epidemiology
- COVID-19 and Mental Health
- Plant Virus Research Studies
- Celiac Disease Research and Management
- SARS-CoV-2 detection and testing
- Polyomavirus and related diseases
- COVID-19 diagnosis using AI
- Respiratory viral infections research
- Pneumonia and Respiratory Infections
Ahvaz Jundishapur University of Medical Sciences
2006-2024
University of Chicago
1982
The SARS-CoV-2 virus has been rapidly spreading globally since December 2019, triggering a pandemic, soon after its emergence. While Iran was among the first countries confronted with rapid spread of in February 2020, no real-time whole-genome tracking early phase outbreak performed country. To address this issue, we provided 50 sequences viral isolates ascertained from different geographical locations during March–July 2020. corresponding analysis on origins, transmission dynamics and...
Complete SARS-CoV-2 genome sequencing in the early phase of outbreak Iran showed two independent viral entries. Subsequently, as part a surveillance project, we aimed to characterize genetic diversity over one year after emerging.We provided 319 whole-genome sequences used monitor circulating lineages March 2020-May 2021 time interval.The temporal dynamics major clades/lineages is comparable global perspective and represent 19A clade (B.4) dominating first disease wave, followed by 20A...
Background: Human rotaviruses are the most important agents for severe dehydrating diarrhea in children below 5 years old. Rotaviruses (RV) is a serious public health problem developing and developed countries. Objectives: The aim of this study was to determine prevalence rotavirus infection their genotypes younger than age with acute Ahvaz, Iran. Materials Methods: For study, 200 stool samples from were collected between October 2011 March 2012. Initially all tested antigen by ELISA,...
Breast cancer is the most common cause of death among women worldwide. Although there are many known risk factors in breast development, infectious diseases have appeared as one important key to contribute carcinogenesis formation. The effects Human Cytomegalovirus (HCMV) on with has been recently studied and reported. To this research trend, study was conducted evaluate association between HCMV cancer. Objective: This experiment aimed DNA Ahvaz city, Iran. Materials Methods: A total 37...
CONTEXT: Celiac disease, one of the best-known autoimmune human leukocyte antigen-dependent disorders, has a relatively increased prevalence in first-degree relatives. OBJECTIVE: To determine celiac disease siblings patients with confirmed disease. METHODS: Siblings our center were identified and enrolled this study. Their serum immunoglobulin A tissue transglutaminase antibody-enzyme-linked immunosorbent assay (anti-tissue transglutaminase, A, G) measured multiple endoscopic duodenal biopsy...
Group A rotavirus (RVA) mainly causes acute gastroenteritis, exclusively in young children developing countries. The prevalence and determination of the molecular epidemiology genotypes will determine dominant region provide a strategy for development appropriate vaccines.A total 100 fecal samples were collected from below five years with gastroenteritis who referred to Aboozar Children’s Hospital Ahvaz city during October 2015 March 2016. All screened by latex agglutination presence...
Background and Objectives: Hepatitis C virus Human Immunodeficiency Virus (HIV) share the same rate of transmis- sion. HIV/HCV co-infected individuals may result in faster progression liver fibrosis highly increase risk cir- rhosis, hepatocellular carcinoma development. Thus this study was conducted to determine co-infection HCV genotypes positive HIV patients Ahvaz city, Iran. Materials Methods: The sera samples were collected from confirmed 78 infected HIV, 67 (85.89%) males 11 (14.1%)...
Non-structural protein 4 (NSP4) is a critical for rotavirus (RV) replication and assembly. This has multiple domains motifs that predispose its function activity. NSP4 sequence divergence in human animal RVs. Recently, 14 genotypes (E1-E14) of have been identified, E1 E2 shown to be the most common human.The gene RV-positive samples were inspected with aim genotyping variation analysis viroporin other domains. P G typings RV carried out by WHO primers using semi-multiplex PCR method....
Human cytomegalovirus (HCMV) is prevalent viral infection involved in several human cancers including breast cancer. The presence of HCMV genome cancer tissue and footprint last exposure patient's serum are considered as important factor the process development.This study aimed to investigate molecular serological epidemiology patients with Iran for first time.In our case-control study, 98 samples tissue, 49 cancerous (case) adjacent non-cancerous were collected (control). In addition, we...
Interleukin-6 (IL-6) is a well-known proinflammatory cytokine with tumor promoting capacity in various forms of malignancies including breast cancer (BC). Data highlighted the substantial role HPV pathogenesis BC. Compelling evidence suggests contribution carcinogenesis through triggering inflammatory cytokines such as IL-6.Here, we assessed correlation between presence infection and status IL-6 expression serum level BC.72 tissue specimens tumoral (Case; n=36) their adjacent normal tissues...
Several viruses are responsible for aseptic meningitis; however, in the region of Southwest Iran, role played by each virus is still not very well known. The aim this study to determine relative frequencies mumps virus, herpes viruses, and enteroviruses, as coinfections among them, patients with meningitis. In cross-sectional study, samples cerebrospinal fluid were collected between December 2012 2013 from under 14 years, who hospitalized Abuzar Children's Hospital Ahvaz, Iran (the only...
The rotavirus is one of the major factors inducing acute gastroenteritis infection in children under 5 years age. laboratory diagnosis progress and bringing it control as well avoiding its diffusion. purpose present study was to determine performance enzyme linked immunosorbent assay (ELISA) Latex agglutination (LA) tests against reverse transcription-polymerase chain reaction (RT-PCR) for evaluating children’s by rotavirus. One hundred feces specimens were collected from February May 2014...
The emergence of a highly pathogenic virus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) accounts for pneumonia throughout the world. More than 7 million world population have been infected with SARS-CoV-2, and number deaths is increasing every day. This study aimed to evaluate frequency SARS-CoV-2 in hospitalized patients infection (ARI). During an outbreak nasopharyngeal oropharyngeal swabs were collected from 909 pneumonia, including 517 (56.9%) males 392 (43.1%)...
Host factors including single-nucleotide polymorphisms (SNPs) in or near interferon lambda (IFNL) gene are the important predicting response to treatment of chronic hepatitis C (CHC).The aim this study was determine frequency and association IFNL4 rs368234815 with IFNL3 SNPs rs12979860, rs8099917 other cholesterol, alanine aminotransferase, fibrosis, viral load, age body mass index genotype 1a treated CHC patients, achieve rapid virologic (RVR) sustained (SVR).A total 71 virus patients were...
The aim of this study was to investigate the prevalence occult hepatitis C virus (HCV) infection (OCI) among HD patients. Blood samples were taken from 79 patients and their sera evaluated for presence anti-HCV. Both peripheral blood mononuclear cells (PBMCs) then checked HCV RNA by nested reverse transcriptase-polymerase chain reaction. Anti-HCV positive 4/79 (5.1%) From 75 who negative anti-HCV, 71 (94.7%) also in but five them PBMCs. Totally, out patients, detected PBMCs (6.3%) indicating...
Background: Human Parvovirus 4 (P4) is a non-enveloped, single-stranded DNA virus belonging to the Tetraparvovirus genus within Parvoviridae family. Epidemiologically, P4 exhibits similarities with its well-established family member, primate erythroparvovirus 1 (known as B19), blood-borne implicated in causing aplastic crises individuals sickle cell disease (SCD). Despite acknowledged association B19, there dearth of prior investigations into prevalence and clinical significance SCD...
Due to the abundance of ACE2 receptors in nervous system cells, SARS-CoV-2 virus can cause damage this system. This study aims examine prevalence neurological symptoms COVID-19 patients. In cross-sectional observational study, 75 positive patients admitted Golestan Hospital’s neurology department Ahvaz, Iran, from March 2020 2023, were investigated. Neurological clinical categorized into three groups: central system, peripheral, and muscular symptoms. The relevant information was collected...
Gastric cancer (GC) is the third most common cause of cancer-related mortality. Epstein-Barr virus (EBV) associated with several human tumors. The present research was performed to investigate prevalence EBV-associated gastric (EBVaGC) among Iranian patients.
Vitamin D deficiency in viral infection associated with autoimmune diseases is well documented. This study assessed the prevalence of JC virus patients rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE), its correlation vitamin level.
Abstract The SARS-CoV-2 virus has been rapidly spreading globally since December 2019, triggering a pandemic, soon after its emergence, with now more than one million deaths around the world. While Iran was among first countries confronted rapid spread of in February, no real-time whole-genome tracking is performed country. To address this issue, we provided 50 sequences viral isolates ascertained from different geographical locations during March-July 2020. corresponding analysis on...
Background: Global real-time monitoring of SARS-CoV-2 variants is crucial to controlling the COVID-19 outbreak. The purpose this study was set up a Sanger-based platform for massive variant tracking in laboratories low-resource settings. Methods: We used nested RT-PCR assay, Sanger sequencing and lineage assignment 930-bp spike gene, which harbors specific concern (VOCs) mutations. our by comparing its results with whole genome (WGS) data on 137 positive samples. Then, we applied it 1028...
Diabetes is recognized as a great concern and public health problem worldwide. Several factors including environmental genetic have been involved. Recently, infectious agents such hepatitis C virus (HCV) reported to be associated with diabetes. Thus, this study was conducted determine the frequency of HCV infection among patients diabetes type 2 in Ahvaz city, Iran.A case-control design at Jundishapur University Medical Sciences. A total 600 subjects were included research. All patient sera...
Background: Diarrhea is one of the most significant diseases in children, causing morbidity and mortality worldwide. caused by viruses, bacteria, parasites. There are several viruses that can cause diarrhea, including some groups enteroviruses have a role acute diarrhea children. Objectives: This study was conducted to evaluate presence stool children with diarrhea. Methods: We collected 85 samples 50 (58.82%) from males 35 (41.17%) females All proved negative for bacterial parasitic...