A5038263043- HIV Research and Treatment
- Hepatitis B Virus Studies
- Viral gastroenteritis research and epidemiology
- Cervical Cancer and HPV Research
- HIV/AIDS drug development and treatment
- Herpesvirus Infections and Treatments
- Antibiotic Resistance in Bacteria
- Systemic Sclerosis and Related Diseases
- SARS-CoV-2 and COVID-19 Research
- Antibiotic Use and Resistance
- Genital Health and Disease
- Animal Virus Infections Studies
- Toxoplasma gondii Research Studies
- Hepatitis C virus research
- Cytomegalovirus and herpesvirus research
- Systemic Lupus Erythematosus Research
- HIV/AIDS Research and Interventions
- RNA Interference and Gene Delivery
- Streptococcal Infections and Treatments
- COVID-19 Clinical Research Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Circular RNAs in diseases
- Antimicrobial Resistance in Staphylococcus
- Antimicrobial agents and applications
- MicroRNA in disease regulation
Kashan University of Medical Sciences
2014-2023
Mashhad University of Medical Sciences
2018
University of Kashan
2016
Shiraz University
2007-2008
Tokushima University
2004-2007
Abstract ToRCH infections (toxoplasmosis, rubella, cytomegalovirus and Herpes simplex virus) have long been known to be associated with bad obstetric outcomes. However, little information is available about the impact of co‐infections on outcome pregnancy. Hence, we tested IgG IgM antibodies T oxoplasma gondii , Rubella, Cytomegalovirus Simplex Virus among 81 pregnant women abortion (case group) 98 normal delivery (control group). In single‐infection model, only CMV ‐ seropositivity was...
Background: Systemic lupus erythematosus (SLE) is an autoimmune disease for whose pathogenesis viral infections are important. The Epstein-Barr virus (EBV) the main infectious etiological agent. This study aimed to quantitative evaluation of EBV in SLE patients. Materials and Methods: In this cross-sectional study, 40 patients with diagnosed based on American College Rheumatology criteria were selected using purposive sampling. All included after obtaining informed consent participation....
Objectives: This study was aimed to evaluate the role of toxoplasmosis in etiology abortion and stillbirth based on molecular serological techniques.Material methods: A total 110 pregnant women with were enrolled as case group, normal delivery control group. Serological detections Toxoplasma gondii assessed by ELISA PCR methods.Results: The seroprevalence IgG 25.5% group (26.8% 21.4% stillbirth) 26.4% IgM seropositivity detected 2.7% (3.6% 0% 0.9% (p = 0.37). DNA 6.4% (7.3% 3.6% 1.8% 0.17)....
Cervical cancer is one of the leading causes cancer-related death in females. Human papilloma virus (HPV) major risk factor cervical cancer.The aim current study was to explore frequency and role 23 different HPVs patients with cancer.Overall, 117 formalin-fix paraffin-embedded (FFPE) tissues from squamous cell carcinoma (SCC) or dysplasia were collected Mirza-Kochakkhan-Jangali hospital, Tehran, Iran during year 2013, investigate presence HPV- 67, 68, 6, 11, 13, 16, 17, 30, 69, 39, 40, 42,...
Coagulase-negative staphylococci (CoNS) are opportunistic pathogens. Methicillin resistance is common in CoNS and may play an important role as reservoir of staphylococcal cassette chromosome mec (SCCmec) for Staphylococcus aureus.The aim this study was to determine molecular characteristics nasal carriage methicillin-resistant coagulase negative among students.MR-CoNS from both nares students were collected. Resistance methicillin determined by cefoxitin (30μg) disk diffusion test. SCCmec...
The sensitivity of a Us3-deletion mutant virus herpes simplex type 1 (HSV-1) to consensus interferon (IFN) was compared with that parental wild-type (wt) and the repaired viruses. Although one-step growth Us3-deficient in IFN-treated HEp-2 cells not markedly affected at high multiplicity infection (MOI), both progeny yield cytopathic effect were suppressed significantly higher degree virus-infected than those wt or cells. This enhanced IFN-sensitivity more clearly demonstrated by low MOI. In...
To evaluate natural killer (NK) cells activity in breast cancer patients and its comparison with normal individuals.Breast is the most prevalent type of spontaneous tumor humans, NK are first line defense against such tumors. There a reverse correlation between metastasis reducing mass by surgery may be monitoring activity. In this study, we pre post mastectomy patients.Eighteen invasive ductal carcinoma attended to research institute were included study. evaluated patients. PBMCs isolated...
Introduction: Interleukins-6 and -8 are two pro-inflammatory cytokines increasing in serum local levels under malignant conditions. There limited evidences on the association between cervical level of these factors intraepithelial neoplasia (CIN). So, this study aimed to explore IL-6 IL-8 with premalignant lesions. Methods: The present case-control was conducted married women undergone Pap smear for routine screening groups as group CIN (n=100) healthy control (n=100). Cervical secretions...
Klebsiella pneumoniae carbapenemase (KPC)-producing bacteria are among the highly antimicrobial resistant gram negative and infections due to them an increasingly major health problem worldwide.In this study we have detected blaKPC blaGES genes in isolated from hospitalized patients Kashan, Iran. In a cross-sectional study, total of 181 K. isolates were recovered clinical specimens during November 2013 October 2014.Antimicrobial susceptibility profiles determined using disk diffusion method...
We have established a number of 293T cell lines that express human anti HIV-1 factor APOBEC3G. Out seven clones examined, four were readily demonstrated to APOBEC3G by immunoblotting analysis. In particular, two (A3G-C1 and -C4) found produce much higher level functional relative pooled clones. The transfection efficiency all these similar the parental cells, producing comparable virions upon wild type vif-minus proviral DNA Furthermore, expression in best line (A3G-C1) was far than those an...
We previously demonstrated that the expression in cells of human immunodeficiency virus type 1 (HIV-1) Vif is maintained at low level by proteasome-degradation. examined contribution 16 lysines present (NL432 clone), which composed 192 amino acids (aa), to its within and viral infectivity for non-permissive cells. To this end, various lysine-arginine mutations were introduced into wild-type (wt) Vif, mutational effects monitored transfection experiments. When all changed arginines, mutant...
Helicobacter pylori (H. pylori) is an important and common contagious human pathogen which may cause peptic ulcer also gastric cancer. The definite diagnosis of it made through invasive tests. Recently, non-invasive tests including serologic serum saliva have been conducted for H. infection. In this research, the diagnostic values salivary serology were compared together to use anti-H. test as alternative method in future.During prospective case-control study on patients who candidates...