A5086836099- Brucella: diagnosis, epidemiology, treatment
- COVID-19 Clinical Research Studies
- Burkholderia infections and melioidosis
- SARS-CoV-2 and COVID-19 Research
- Antibiotic Resistance in Bacteria
- Galectins and Cancer Biology
- Long-Term Effects of COVID-19
- Hepatitis B Virus Studies
- Bacterial Identification and Susceptibility Testing
- Hepatitis Viruses Studies and Epidemiology
- Escherichia coli research studies
- Antibiotic Use and Resistance
- Vibrio bacteria research studies
- Vitamin C and Antioxidants Research
- Viral gastroenteritis research and epidemiology
- Infectious Diseases and Tuberculosis
- COVID-19 epidemiological studies
- Tuberculosis Research and Epidemiology
- MicroRNA in disease regulation
- Hepatitis C virus research
- Leptospirosis research and findings
- Diagnosis and treatment of tuberculosis
- COVID-19 and healthcare impacts
- Bacterial biofilms and quorum sensing
- COVID-19 diagnosis using AI
Hamedan University of Medical Sciences
2013-2024
Universidad de Ciencias Medicas
2024
Sina Hospital
2006-2023
Yazd University
2020
Office of Infectious Diseases
2009
Importance The protein-based SARS-CoV-2 vaccines FINLAY-FR-2 (Soberana 02) and FINLAY-FR-1A Plus) showed good safety immunogenicity in phase 1 2 trials, but the clinical efficacy of vaccine remains unknown. Objective To evaluate a 2-dose regimen (cohort 1) 3-dose with 2) Iranian adults. Design, Setting, Participants A multicenter, randomized, double-blind, placebo-controlled, 3 trial was conducted at 6 cities cohort 2. included individuals aged 18 to 80 years without uncontrolled...
To determine the frequency and clinical characteristics of osteoarticular complications brucellosis in an endemic region Iran.In a prospective study we evaluated 245 patients with diagnosed between January 2004 December 2005. Patients included were those older than 8 years age who had features suggestive specific antibodies at significant titers, and/or positive blood or body fluid culture for Brucella species. A bone scan was performed suspicion involvement.Seventy (28.6%) complications....
Traditional regimens for the treatment of brucellosis are associated with significant relapse rates. The aim this study was to compare efficacy ofloxacin plus rifampin (OFX-RIF) versus doxycycline streptomycin (DOX-STR) and (DOX-RIF) in brucellosis.Two hundred nineteen patients were enrolled a randomized clinical trial; 28 cases withdrawn because they did not attend follow-up. Out 191 brucellosis, 64 received OFX-RIF, 62 DOX-RIF, 65 DOX-STR regimens. All assessed during period therapy...
Abstract Background Pseudomonas aeruginosa is a common co-infecting pathogen recognized among COVID-19 patients. We aimed to investigate the antimicrobial resistance patterns and molecular typing of isolates Coronavirus disease-19 Methods Between December 2020 July 2021, 15 were isolated from patients in intensive care unit at Sina Hospital Hamadan, west Iran. The was determined by disk diffusion broth microdilution methods. double-disk synergy method, Modified Hodge test, polymerase chain...
Tuberculosis is one of the oldest infections known to affect humans. The aim study was assess quality life including physiological, general health perception and social role functioning among patients with tuberculosis in Hamadan, Western Iran.A cross sectional analytical conducted between December 2009 March 2011, scores 64 cases were measured by SF-36 questionnaire before treatment, after initial phase at end treatment compared those 120 controls. association age, type tuberculosis, sputum...
An important number of studies have been conducted on the potential association between human leukocyte antigen (HLA) genes and COVID-19 susceptibility severity since beginning pandemic. However, case-control peptide-binding prediction methods tended to provide inconsistent conclusions risk protective HLA alleles, whereas some researchers suggested importance considering overall capacity an individual's Class I molecules present SARS-CoV-2-derived peptides. To close gap these approaches, we...
BackgroundCombination drug therapy of brucellosis leads to recovery symptoms, shortening symptomatic interval, and decrease in morbidity rate, but single is associated with more relapse episodes a higher rate resistance. Different combinations have been evaluated the treatment brucellosis. Considering failure relatively high disease World Health Organization's (WHO) recommended therapeutic regimen, we new regimen that assumed would increase success relapse. In this study compare standard...
There are various phenotypic methods for identifying class B and A β-lactamase enzymes in Pseudomonas aeruginosa. The purpose of this study was to compare the sensitivity specificity different with HRMA assay detect β-lactamase-producing P. aeruginosa strains.Eighty-eight isolates were collected from specimens. Conventional double-disk test (DDT) EDTA-imipenem microbiological (EIM) performed ESBL MBL-producing strains, respectively. Meanwhile, Modified Hodge Carba-NP on all...
This study was designed to compare the efficacy of ciprofloxacin plus rifampin (CR) and doxycycline (CD) versus (DR) in treatment brucellosis. A total 178 patients with brucellosis who were referred Sina Hospital, Hamedan, Iran, included. The responses therapy observed 166 cases (93.7%) – 59 DR group, CR group 48 CD group. No significant differences therapeutic ( P = 0.09). Relapse 11.7% (DR 7.7%, 8.3% 17.5%) after a six-month follow-up. also relapse rates among three groups 0.35). We...
The concentration of diagnostic markers such as inflammatory biomarkers including procalcitonin (PCT) and C-reactive protein (CRP) increases in bacterial infections. aim this study was to compare serum PCT CRP levels with CURB-65 ranking, the patients community-acquired pneumonia (CAP).In a cross-sectional study, 93 hospitalized definite diagnosis CAP, considering inclusion exclusion criteria, were enrolled. Serum their relations criteria assessed.The mean 3.64±12.32 ng/mL 75.01±51.93 mg/L,...
Abstract Background Multi-drug resistant (MDR) Acinetobacter baumannii is one of the most important causes nosocomial infections. The purpose this study was to identify antibiotic resistance patterns, biofilm formation and clonal relationship clinical environmental isolates A. by Pulsed Field Gel Electrophoresis method. Forty-three 26 MDR were collected recognized via API 20NE. Antibiotic assessed disk diffusion method, test done microtiter plate (PFGE) used assess genomic features bacterial...
Complete SARS-CoV-2 genome sequencing in the early phase of outbreak Iran showed two independent viral entries. Subsequently, as part a surveillance project, we aimed to characterize genetic diversity over one year after emerging.We provided 319 whole-genome sequences used monitor circulating lineages March 2020-May 2021 time interval.The temporal dynamics major clades/lineages is comparable global perspective and represent 19A clade (B.4) dominating first disease wave, followed by 20A...