A5074747983- SARS-CoV-2 and COVID-19 Research
- Hepatitis C virus research
- Hepatitis B Virus Studies
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Influenza Virus Research Studies
- Liver Disease Diagnosis and Treatment
- Diagnosis and treatment of tuberculosis
- Antibiotic Use and Resistance
- Vaccine Coverage and Hesitancy
- Viral Infections and Vectors
- Pneumonia and Respiratory Infections
- COVID-19 epidemiological studies
- Infectious Diseases and Tuberculosis
- Antifungal resistance and susceptibility
- Hepatitis Viruses Studies and Epidemiology
- Fungal Infections and Studies
- Viral gastroenteritis research and epidemiology
- Parasite Biology and Host Interactions
- Nail Diseases and Treatments
- Virology and Viral Diseases
- Cutaneous lymphoproliferative disorders research
- Bacillus and Francisella bacterial research
Mazandaran University of Medical Sciences
2014-2024
Tehran University of Medical Sciences
2024
Razi Hospital
2011-2022
Ghaem Hospital
2011-2020
Baqiyatallah University of Medical Sciences
2013-2017
Abstract Background New therapeutic options are urgently needed to tackle the novel coronavirus disease 2019 (COVID-19). Repurposing existing pharmaceuticals provides an immediate treatment opportunity. We assessed efficacy of sofosbuvir and daclatasvir with ribavirin for treating patients COVID-19. Methods This was a single-centre, randomized controlled trial in adults moderate COVID-19 admitted Ghaem Shahr Razi Hospital Mazandaran Province, Iran. Patients were randomly assigned 400 mg...
The Sputnik V is a COVID- 19 vaccine developed by the Gamalia institute of epidemiology and microbiology released on August 11, 2020. We provided independent evidence side effects immunogenicity following administration COVID-19 in Iran. In this observational study, healthcare workers who were vaccinated with within February April 2021 evaluated. Among total 13,435 workers, we received 3236 self-declaration reports associated adverse events mean age 39.32 ± 10.19 years old which 38.8% men...
Abstract Background We performed a multicenter, randomized open-label trial in patients with moderate to severe Covid-19 treated range of possible treatment regimens. Methods: Patients were randomly assigned one three regimen groups at ratio 1:1:1. The primary outcome this study was admission the intensive care unit. Secondary outcomes intubation, in-hospital mortality, time clinical recovery, and length hospital stay (LOS). Between April 13 August 9, 2020, total 336 receive 3 regimens...
Background . Mycobacterium tuberculosis ( M.TB ) causes a wide spectrum of clinical diseases. The prevalence TB is different in various parts Iran and throughout the world. present study aimed to determine epidemiology paraclinical findings TB. Methods A cross-sectional was conducted from 2008 2013. Patient demographic, clinical, radiologic characteristics, picked up patient’s files, were collected using standard questionnaire format. Data entered analyzed SPSS version 16 statistical...
Background . Herpes zoster infection is a painful worldwide disease. Inappropriate and delayed treatment causes prolongation of the disease with debilitating symptoms postherpetic neuralgia. Method A cross-sectional study evaluated shingles cases admitted in teaching hospital one-year followup north Iran from 2007 to 2013. Results From 132 patients, 60.4% were male. Head neck involvement occurred 78 people (59.1%), thoracoabdominal region 37 (28%), extremities 16 (12.1%), one case (0.8%) got...
The combination of sofosbuvir and daclatasvir has shown preliminary efficacy for hospitalized patients with COVID-19 in four open-label studies small sample sizes. This larger trial aimed to assess if the addition sofosbuvir/daclatasvir standard care improved clinical outcomes COVID-19.This was a placebo-controlled, double-blind, randomized adults at 19 hospitals Iran. Patients were oral 400/60 mg once-daily or placebo care. included they had positive PCR diagnostic chest CT, O2 saturation...
Ivermectin which was widely considered as a potential treatment for COVID-19, showed uncertain clinical benefit in many trials. Performing large-scale trials to evaluate the effectiveness of this drug midst pandemic, while difficult, has been urgently needed.We performed two large multicenter randomized, double-blind, placebo-controlled evaluating ivermectin treating inpatients and outpatients with COVID-19 infection. The intervention group received ivermectin, 0.4mg/kg body weight per day 3...
Introduction The occurrence of oral candidiasis (OC) is expected in patients with COVID-19, especially those moderate to severe forms infection who are hospitalized and may be on long-term use broad-spectrum antibiotics or prolonged corticosteroid therapy. We aimed characterize clinical conditions, the prevalence profile Candida species, outcomes COVID-19 OC. Methods In this observational study, samples were obtained from suspected OC admitted Razi teaching hospital. Patients monitored daily...
The relationship between compromised immune system and the development of malignancy, generalized dermatitis, infection after sulfur mustard gas exposure has been established.We introduce a 58-year-old man with an abrupt, de novo erythrodermic eruption in 2002 that was previously exposed to during Iran - Iraq war 1987. Six weeks onset diffuse eruption, he developed papules on glans penis dermatophytosis. A biopsy his consistent cutaneous T-cell lymphoma/Sézary syndrome. complete blood count...
Background: Albinos in Africa are at constant risk of developing skin cancer due to the damage caused by ultra-violet exposure. This study identifies common conditions among albinos Kenya as a country located along equator. Methods: In this descriptive on albino patients who were admitted Mbagathi District Hospital Nairobi, census method was used for sampling and total 151 registered. All necessary data including age, gender, type, site number lesions recorded. Suspected with malignant...
Complete SARS-CoV-2 genome sequencing in the early phase of outbreak Iran showed two independent viral entries. Subsequently, as part a surveillance project, we aimed to characterize genetic diversity over one year after emerging.We provided 319 whole-genome sequences used monitor circulating lineages March 2020-May 2021 time interval.The temporal dynamics major clades/lineages is comparable global perspective and represent 19A clade (B.4) dominating first disease wave, followed by 20A...
Background: Iraq used chemical weapons against thousands of Iranian militaries and civilians. This study aimed to compare the chronic cutaneous side effects exposure sulfur mustard (SM) with nerve agents (NA).Methods: The enrolled 154 SM exposed cases 175 (NA) cases. Presence any late manifestations was evaluated by a dermatologist via prior history acute complications extracted from medical achieves.Results: only 18.1% group asymptomatic compared 62.4% agent exposures. Mustard non-mustard...
Empyema necessitans (EN) is a kind of empyema that diffuses to extrapleural space and can involve chest pain. Tuberculosis (TB) the most common cause EN. This disease be found in both immunocompromised immunocompetent individuals but usually seen individuals. Because long duration ambiguous symptoms disease, diagnosis hard. The treated medically surgically. Missing lead undesirable effects on patient’s condition health care setting. problem endemic area which controlling TB Report local...
Brucellosis is an infectious disease caused by gram-negative bacteria of the genus Brucella. Involvement gastrointestinal, hepatobilliary, and skeletal systems has been reported frequently in literature. nervous system relatively uncommon only 3%-25% cases generalized brucellosis. Guillain-Barré syndrome a prototypical postinfectious autoimmune disease. We report case 26-year-old woman as presentation neurobrucellosis.
What is known and objective Although antibiotics are ineffective against viral infections, epidemiological studies have revealed that the COVID-19 pandemic resulted in overuse of disruption antimicrobial stewardship programmes. We investigated pattern antibiotic use during first 6 months Iran. Methods A multi-centre retrospective study was designed to investigate 16 broad-spectrum 12 medical centres. The rate calculated reported based on Defined Daily Dose (DDD) per 100 hospital bed-days....
Diabetes is the most common metabolic disease in humans. One of major complications foot ulcer that prone to infection. The causes infection which have been reported these patients are bacteria and fungi such as Candida, Aspergillus, Rhizopus species. We report one rare case with calcaneal osteomyelitis caused by Aspergillus ochraceus a patient diabetic osteomyelitis. was 68-year-old male history type II diabetes for 2 years. had two ulcers on right heel bones past 6 months no significant...