A5001260287- Genomics, phytochemicals, and oxidative stress
- MicroRNA in disease regulation
- SARS-CoV-2 and COVID-19 Research
- Glutathione Transferases and Polymorphisms
- Circular RNAs in diseases
- Infection Control and Ventilation
- SARS-CoV-2 detection and testing
- COVID-19 epidemiological studies
- COVID-19 Clinical Research Studies
- COVID-19 and healthcare impacts
- Epigenetics and DNA Methylation
- Cancer-related molecular mechanisms research
- Viral Infections and Vectors
- COVID-19 impact on air quality
- Metabolism, Diabetes, and Cancer
- Saffron Plant Research Studies
- Hedgehog Signaling Pathway Studies
- Healthcare and Environmental Waste Management
- Kruppel-like factors research
- Mosquito-borne diseases and control
- Animal Virus Infections Studies
- Curcumin's Biomedical Applications
- Family Support in Illness
- RNA modifications and cancer
- Medicinal Plants and Bioactive Compounds
Ardabil University of Medical Sciences
2018-2025
Tabriz University of Medical Sciences
2017
Université Ibn-Tofail
2013
Tehran University of Medical Sciences
2011
This study is designed to assess the effect of root extract P. ginseng on kidney tissue injury attributed cisplatin and its molecular mechanism involved in this process AKI rat model. Twenty-four male Wistar rats were randomly allocated into 4 experimental groups including: control group, 100 mg/kg 200 group. The duration investigation was 7 days, all except group received a single dose 10 4th day. Our findings exhibited significant reduction blood concentration creatinine compared In severe...
Crimean-Congo hemorrhagic fever (CCHF) is one of the most acute tick-transmitted zoonotic diseases. The purpose this study was to determine molecular characteristics and phylogenetic analysis CCHF virus based on S-segment nucleocapsid gene in Ardabil Province, northwestern Iran. From November 2021 May 2023, a total 20 peripheral blood specimens were collected from suspected patients. Following RNA extraction, partial nucleotide sequence S fragment amplified (536 bp) using one-step RT-PCR...
Background: The L-asparaginase enzyme is used as an anticancer agent in treating acute lymphoblastic leukemia (ALL). Moreover, it has widespread applications medicine, food, and pharmaceutical industries. Methods: nucleotide amino acid sequences of derived from Bacillus subtilis BEST7613, Kibdelosporangium sp. MJ126-NF4, Thermococcus kodakarensis KOD1 have been obtained the GenBank NCBI databases. EMBOSS Water pairwise sequence alignments were performed using ClustalW 1.83. Prediction...
The SARS-CoV-2 virus has been rapidly spreading globally since December 2019, triggering a pandemic, soon after its emergence. While Iran was among the first countries confronted with rapid spread of in February 2020, no real-time whole-genome tracking early phase outbreak performed country. To address this issue, we provided 50 sequences viral isolates ascertained from different geographical locations during March–July 2020. corresponding analysis on origins, transmission dynamics and...
MicroRNAs (miRNAs), as a class of nonprotein-coding RNAs, post-transcriptionally regulate the expression target genes by base pairing to 3'-untranslated regions (3'-UTRs). Nuclear factor E2-related 2 (Nrf2) has been identified critical component antioxidant defense mechanism. Dysregulation is associated with chemoresistance and radioresistance in cancerous cells. MiRNA-mediated regulation Nrf2 signaling pathway shown have important implications for development various cancers. In this...
Abstract DNA methylation is an important molecular modification that plays a key role in the expression of cancer genes. Evaluation epigenetic changes, hypomethylation and hypermethylation, specific genes are applied for diagnosis. Numerous studies have concentrated on describing patterns as biomarkers diagnosis monitoring predicting response to therapy. Various techniques detecting status cancers based sodium bisulfite treatment. According application these methods research clinical...
Abstract Background Say–Barber–Biesecker–Young–Simpson (SBBYS) (OMIM #603736, Ohdo syndrome variant) is a rare type of severe blepharophimosis intellectual disability syndrome, which generally characterized by global developmental delay, distinctive facial features, and with multiple congenital anomalies, including skeletal involvement, missing, or underdeveloped kneecaps, genital in affected males. It has been shown that mutations the KAT6B gene, lysine acetyltransferase-encoding have...
The presence of SARS-CoV-2 virus in water resources and the transmission diseases caused by it is one factors threatening quality resources. This study for first time concentrates on an urban location. In present study, samples were collected from known depth (30-50 cm) rivers, dams lakes. each sample collected, different parameters such as residual chlorine, pH (phenol red), turbidity, total dissolved solids temperature also measured. Out 267 samples, two detected to be positive which their...
Abstract Introduction Nigella sativa ( N. ), one of the most commonly used medicinal herbs with antioxidant properties, increases blood insulin levels and lowers fasting sugar. Nuclear Erythroid Factor-Related Factor 2 (Nrf2) Fibroblast Growth 21 (FGF21) are two factors that increased by oxidative stress hyperglycemia. The present study investigated how hydroalcoholic extract seed (HENS) levels, taking into account changes in expression transcription factors. Materials methods Two groups...