A5062728987- Cancer-related molecular mechanisms research
- Photovoltaic Systems and Sustainability
- Energy and Environment Impacts
- Circular RNAs in diseases
- Hippo pathway signaling and YAP/TAZ
- RNA Research and Splicing
- Health, Environment, Cognitive Aging
Zhongshan Hospital of Xiamen University
2022-2023
Abstract Background： Otosclerosis is a primary bone disease caused by the labyrinth, resorption, and abnormal deposition. According to current research, it complex related genetic environmental factors. However, molecular mechanism associated with otosclerosis has not been clearly revealed. Methods： The purpose of this study was screen differentially expressed genes (DEGs) in patients corresponding normal controls RNA sequencing (RNA-Seq) then deal DEGS weighted gene co-expression network...
Abstract Background Hearing loss (HL) is a public health event, which seriously affects the happiness of people’s life. Hsa-miR-124-5p has not been reported in HL. This study aimed to construct miRNA-mRNA network associated with Methods Subjects were screened through clinical audiology experiments. MiRNA-seq was performed on peripheral blood mononuclear cells (PBMC), and differentially expressed miRNAs (DEMs, P -Value < 0.05, ∣log FC | ≥1) obtained by analysis. We selected most...