A5042257640- Particle physics theoretical and experimental studies
- High-Energy Particle Collisions Research
- Particle Detector Development and Performance
- Quantum Chromodynamics and Particle Interactions
- Dark Matter and Cosmic Phenomena
- Computational Physics and Python Applications
- Neutrino Physics Research
- Prostate Cancer Treatment and Research
- Cosmology and Gravitation Theories
- Radiation Detection and Scintillator Technologies
- Distributed and Parallel Computing Systems
- Microscopic Colitis
- Inflammatory Bowel Disease
- Prostate Cancer Diagnosis and Treatment
- Renal cell carcinoma treatment
- Astrophysics and Cosmic Phenomena
- Medical Imaging Techniques and Applications
- Radiomics and Machine Learning in Medical Imaging
- Cancer, Lipids, and Metabolism
- Eosinophilic Esophagitis
- Liver Disease Diagnosis and Treatment
- advanced mathematical theories
- Superconducting Materials and Applications
- Cancer Genomics and Diagnostics
- Advanced Data Storage Technologies
Argonne National Laboratory
2016-2025
Veracyte (United States)
2022-2025
Northern Illinois University
2021-2024
A. Alikhanyan National Laboratory
2024
Atlas Scientific (United States)
2024
The University of Adelaide
2022-2023
University of California, San Diego
2013-2022
University of San Diego
2021
Allergan (United States)
2021
Santen (Japan)
2021
Previous studies have demonstrated nurses are at risk of suicide. This is the first national longitudinal study U.S. nurse suicide.To identify incidence, method, and risks suicide in United States.2005 to 2016 Centers for Disease Control Prevention National Violent Death Reporting System retrospective analysis incident rate ratios (IRR).A total 1,824 152,495 non-nurse suicides were evaluated. Nurses greater than general population (female IRR 1.395, 95% confidence intervals [CI] 1.323,...
With no report on the overall prevalence and ramifications of hepatitis Delta virus (HDV) infection in United States for more than two decades, characteristics chronic B (CHB) patients coinfected with HDV, including clinical presentation, rate C tri-infection, HDV viral load, were assessed.At California Pacific Medical Center, a retrospective chart review was conducted all CHB patients.Of 1191 patients, 499 had been tested 42 (8%) determined to be coinfected; half these also virus-infected....
Summary Background Though pharmacokinetic studies suggest accelerated biologic drug clearance with increasing body weight, evidence of obesity's impact on clinical outcomes in biologic‐treated patients ulcerative colitis ( UC ) is inconsistent. Aim To evaluate the obesity real world response to biological therapy . Methods In a single‐centre retrospective cohort study between 2011‐2016 , we evaluated treatment by baseline mass index BMI ). Primary outcome was failure (composite IBD ‐related...
INTRODUCTION: We conducted a cohort study on the impact of obesity disease activity and Patient-Reported Outcomes Measurement Information System (PROMIS) measures in inflammatory bowel (IBD) Partners cohort. METHODS: performed cross-sectional longitudinal within IBD Partners, an internet-based >15,000 patients living with Crohn's (CD) ulcerative colitis (UC). included adult IBD, recorded body mass index (BMI), at least 6 months follow-up, excluding BMI < 18.5 kg/m 2 . evaluated...
Background Fetal echocardiography can accurately diagnose critical congenital heart disease prenatally, but relies on referrals from abnormalities identified routine obstetrical ultrasounds. Critical that is frequently missed due to inadequate outflow tract imaging includes anomalies such as truncus arteriosus, double outlet right ventricle, transposition of the great arteries, tetralogy Fallot, pulmonary stenosis, and aortic stenosis. Objective This study evaluated prenatal detection rate...
OBJECTIVES: To assess whether obesity may affect response to infliximab, we conducted an individual participant data pooled analysis using from clinical trials of infliximab in inflammatory bowel diseases (IBD), the Yale Open Data Access (YODA) Project. METHODS: We analyzed four adults with IBD (ACCENT-I, SONIC, ACT-1, and -2). Patients were categorized as obese (body mass index [BMI] ≥ 30 kg/m2) vs. non-obese, by quartiles based on BMI or weight at time trial entry. Primary outcome was...
Pediatric patients with cleft lip and palate undergo numerous surgeries throughout their childhood early adulthood to correct the aesthetic functional stigmata of diagnoses. This study identifies patient clinical factors that contribute number anesthesia events children for repair.Retrospective chart review was performed using genetic dysmorphology database at Rady Children's Hospital San Diego. All or diagnosis who underwent surgery Diego between 1988 2014 were included. A sample size 71...
<h3>Abstract</h3> This retrospective, observational study was conducted by collecting data from medical records during COVID 19 pandemic March 2020 till August 2020. compared with the of 2019 similar months. The impact on use preventive and curative paediatric health care service units like outpatient department, casualty, intensive immunization clinic were assessed. Data to using standard parametric nonparametric tests. There a significant decline in routine OPD (68%) attendance period as...
202 Background: While several PARP inhibitors are approved in combination with hormonal therapies for metastatic castrate resistant prostate cancer (CRPC), their use sensitive (CSPC) is understudied. We previously reported that olaparib monotherapy (without ADT) shows significant clinical activity BRCA2 -altered patients biochemically recurrent (BCR) cancer. Here, we explored prognostic and predictive PARP-related mRNA biomarkers derived from primary tumors. Methods: characterized the...
308 Background: NRG/RTOG 0126 and SAKK 09/10 were phase III randomized trials examining whether higher dose resulted in better response/outcomes PCa patients following definitive post-operative RT, respectively. RTOG showed a benefit for RT escalation (DE) from 70.2Gy to 79.2Gy though did not show 64Gy 70Gy. We hypothesized that previously developed 24-gene prostate cancer gene expression score (PORTOS) could distinguish who benefited DE both trials. Methods: PORTOS scores calculated on...
399 Background: The three-arm randomized SPPORT trial (n=1792) examined the effect of treatment intensification on outcome men treated with salvage radiotherapy (RT) for a detectable PSA. arms were prostate bed RT (PBRT) alone (Arm I), PBRT + short term androgen deprivation therapy (STADT; Arm 2), and STADT pelvic lymph node (PLNRT; 3). With in Arms 2 3, there significant incremental gains primary freedom from progression (FFP) endpoint, but not metastasis free survival (MFS) about 8 yr...
419 Background: A third of patients with biochemical recurrence after radiation (RT) have intraprostatic radiorecurrence (IPR) on PSMA PET/CT. Patients IPR worse metastasis-free survival - a surrogate for progression to lethal prostate cancer (PCa). We previously reported the results from our F-SHARP clinical trial that demonstrated salvage reirradiation using focal dose-escalated high dose rate (HDR) brachytherapy is safe and effective. Here, we examine Decipher score determine if it could...
415 Background: Elevated serum levels of tumor necrosis factor alpha (TNF-α) are characteristic chronic inflammatory conditions and advanced prostate cancer (PCa). Local systemic inflammation associated with TNF-α may enhance oncogenicity in the prostate. This study investigates association between intra-tumoral levels, NCCN risk, adverse pathology (AP) at radical prostatectomy (RP), progression on active surveillance (AS). Methods: Intra-tumoral pathway expression were assessed through...
409 Background: Androgen receptor activity (AR-A) has been described after radical prostatectomy (RP) and metastatic castration-sensitive prostate cancer (mCSPC). In RP specimens low AR-A is associated with basal subtypes, decreased DNA repair increased immune activity. mCSPC, poor overall survival (OS) time to progression CRPC. However, not well characterized in localized disease at initial diagnosis. Here we sought assess signatures biopsy samples from patients across the risk continuum...
335 Background: Recent advances in AI have brought innovation to digital pathology problems with H&E whole slide images (WSI). Though some (DPAI) models been developed for survival analysis TCGA data, there is a lack of understanding as how DPAI predict progression free (PFS) the prostate dataset (PRAD). Nor comprehensive comparison versus genomic or clinical models. Batch effects were also ignored prior works. Methods: PRAD contains 392 patients WSI and data. batch effect was first...