A5005453939- HIV/AIDS Research and Interventions
- Maternal Mental Health During Pregnancy and Postpartum
- Mobile Health and mHealth Applications
- HIV-related health complications and treatments
- Health Literacy and Information Accessibility
- HIV Research and Treatment
- Impact of Technology on Adolescents
- HIV, Drug Use, Sexual Risk
- Digital Mental Health Interventions
- Gastric Cancer Management and Outcomes
- Family Caregiving in Mental Illness
- Monoclonal and Polyclonal Antibodies Research
- Immune Cell Function and Interaction
- Adolescent Sexual and Reproductive Health
- Colorectal and Anal Carcinomas
- Adolescent and Pediatric Healthcare
- vaccines and immunoinformatics approaches
- Attachment and Relationship Dynamics
- Gastrointestinal Tumor Research and Treatment
- Mental Health Treatment and Access
- Mental Health Research Topics
Tencent (China)
2023
Guangzhou Medical University
2022
Sun Yat-sen University
2018-2020
Johns Hopkins University
2018
Background People living with HIV (PLWH) have high rates of depressive symptoms. However, only a few effective mental health interventions exist for this vulnerable population. Objective The aim study was to assess the efficacy WeChat-based intervention, Run4Love, randomized controlled trial among 300 people and depression (PLWHD) in China. Methods We recruited PLWH from outpatient clinic South Participants were screened based on Center Epidemiologic Studies-Depression (CES-D) scale. Those...
Most people living with HIV (PLWH) reside in middle- and low-income countries limited access to health services. Thus, cost-effective interventions that can reach a large number of PLWH are urgently needed.The objective our study was assess the feasibility acceptability an mHealth intervention among China.Based on previous formative research, we designed program included sending weekly reminders participants via text messages (short message service, SMS) articles self-management three times...
Structural docking between the adaptive immune receptors (AIRs), including T cell (TCRs) and B (BCRs), their cognate antigens are one of most fundamental processes in immunity. However, current methods for predicting AIR-antigen binding largely rely on sequence-derived features AIRs, omitting structure that essential affinity. In this study, we present a deep learning framework, termed DeepAIR, accurate prediction by integrating both sequence AIRs. DeepAIR achieves Pearson's correlation...
People living with HIV (PLWH) suffer from high rates of mental illness; but targeted effective interventions are limited, especially in developing countries. High penetration smartphone usage and widespread acceptance social media applications provide an unprecedented opportunity for mobile-based health (mHealth interventions) resource-limited settings like China. The current report describes the design sample characteristics Run4Love randomized controlled trial (RCT) aimed at improving PLWH...
Background The dose–response relationship between patient engagement and long-term intervention effects in mobile health (mHealth) interventions are understudied. Studies exploring potentially changing relationships outcomes mHealth needed. Objective This study aims to examine 3 psychosocial an intervention, Run4Love, using repeated measurements of at baseline 3, 6, 9 months. Methods is a secondary analysis longitudinal data from the Run4Love trial, randomized controlled trial with 300...
People living with HIV and depression have high rates of suicide. Studies mobile health (mHealth) interventions shown feasibility, acceptability, efficacy in improving mental people depression. However, few studies examined the mechanisms effects mHealth on suicide.This study was designed to examine a WeChat-based intervention, Run4Love, suicide among China, while considering perceived stress depressive symptoms as mediators.A sample 300 recruited from outpatient clinic large or AIDS...
Background: The prognostic value of tumor deposit (TD) in gastric cancer is controversial. This study aims to investigate the TD. Methods: consecutive patients diagnosed with from October 2007 2012 were selected. divided by whether they suffered TD into two groups. basic data comparable between groups after propensity score matching (PSM), then survival analysis [overall (OS) and cancer-specific (CSS)] was applied After that, all pN staging each subgroup. At last, group, pN1 stage pN2 pN3a,...
Despite a strong evidence on the negative association between HIV-related stigma and quality of life (QoL), few studies have examined indirect effects this relationship. This study aimed to examine QoL positive coping perceived stress in people living with HIV depressive symptoms (PLWHD). used baseline date from randomized controlled trial. Structural equation model was as well stress. Perceived internalized had direct (β = −0.14, p < 0.05) effect QoL. Moreover, through decreased increased...
Unemployment is associated with depression in people living HIV (PLWH). However, few studies have examined the effects of unemployment on PLWH different levels depression. The current study explores plausible differential percentiles employing a quantile regression (QR) approach, based recent survey 411 China. Among participants, 47.7% had elevated depressive symptoms, and 23.8% were unemployed. statistically significant trend initial increase followed by decline at 0.51–0.90 maximum effect...
Background Although several studies have investigated the effects of mobile health (mHealth) interventions on depression among people living with HIV, few explored mediators mHealth-based to improve mental in HIV. Identifying influential may enhance and refine effective components mHealth Objective This study aimed examine mediating factors a intervention, Run4Love, designed reduce HIV using 4 time-point measurement data. Methods used data from randomized controlled trial intervention...
Few studies have examined the relationship between inconsistent condom use and sexual partnership characteristics among people living with HIV (PLWH). The current study focused on such association its gender differences. was conducted in a large hospital South China 2013. A total of 320 dyads (PLWH indexes their partners) were recruited from an outpatient clinic using convenience sampling. proportion last six months female higher than that male (52.4% vs. 43.6%). Of characteristics,...
<sec> <title>BACKGROUND</title> Most people living with HIV (PLWH) reside in middle- and low-income countries limited access to health services. Thus, cost-effective interventions that can reach a large number of PLWH are urgently needed. </sec> <title>OBJECTIVE</title> The objective our study was assess the feasibility acceptability an mHealth intervention among China. <title>METHODS</title> Based on previous formative research, we designed program included sending weekly reminders...
<sec> <title>BACKGROUND</title> People living with HIV and depression have high rates of suicide. Studies mobile health (mHealth) interventions shown feasibility, acceptability, efficacy in improving mental people depression. However, few studies examined the mechanisms effects mHealth on </sec> <title>OBJECTIVE</title> This study was designed to examine a WeChat-based intervention, <italic>Run4Love</italic>, suicide among China, while considering perceived stress depressive...
<sec> <title>BACKGROUND</title> The dose–response relationship between patient engagement and long-term intervention effects in mobile health (mHealth) interventions are understudied. Studies exploring potentially changing relationships outcomes mHealth needed. </sec> <title>OBJECTIVE</title> This study aims to examine 3 psychosocial an intervention, Run4Love, using repeated measurements of at baseline 3, 6, 9 months. <title>METHODS</title> is a secondary analysis longitudinal data from the...