- EEG and Brain-Computer Interfaces
- Functional Brain Connectivity Studies
- Pregnancy and preeclampsia studies
- Traditional Chinese Medicine Studies
- Pharmacological Effects of Natural Compounds
- Healthcare and Venom Research
- Statistical Methods and Inference
- Cardiovascular Health and Risk Factors
- ECG Monitoring and Analysis
- Immune Response and Inflammation
- Nutritional Studies and Diet
- Gestational Diabetes Research and Management
- Trace Elements in Health
- Bariatric Surgery and Outcomes
- Advanced Causal Inference Techniques
- Anorectal Disease Treatments and Outcomes
- Liver Disease Diagnosis and Treatment
- Maternal and fetal healthcare
- Lymphoma Diagnosis and Treatment
- Reproductive System and Pregnancy
- Inflammatory Bowel Disease
- Cardiac electrophysiology and arrhythmias
- Birth, Development, and Health
- Advanced Statistical Methods and Models
- Cancer, Hypoxia, and Metabolism
Sun Yat-sen University
2015-2025
Huazhong Agricultural University
2023-2025
China Agricultural University
2025
Zhejiang University of Water Resource and Electric Power
2024
Zhejiang A & F University
2024
Air Force Medical University
2021-2023
Huawei Technologies (China)
2023
Xijing Hospital
2023
China Medical University
2022
General Hospital of Shenyang Military Region
2022
Abstract Background Most studies have showed that maternal depression is associated with pregnancy complications. However, there were limited evidences in Chinese population. We examined the associations of antenatal symptoms outcomes, especially for low birth weight. Methods A total 1377 singleton pregnant women recruited from Nanshan Maternity & Child Healthcare Hospital Shenzhen this prospective cohort study. Depression assessed by Edinburgh postnatal scale (EPDS) questionnaire second...
The optimization of urban multi-source water supply systems is essential for addressing the growing challenges allocation, cost management, and system resilience in modern cities. This study introduces a graph-theory-based model to analyze structural operational dynamics systems, incorporating constraints such as quality, pressure, connectivity. Using Lishui City case study, evaluates three allocation plans meet projected 2030 demand. Advanced algorithms, including Floyd’s shortest path...
Under the circumstance of global population aging, issue on how to facilitate quality life (QOL) for older people brings us grand challenge. On way solve this problem, it is inextricable measure QOL accurately at onset. This study aimed evaluating reliability and validity Chinese version World Health Organization Quality Life Instrument-Older Adults Module (WHOQOL-OLD).We received 1005 valid WHOQOL-OLD questionnaires from 1050 respondents who were 60 by quota sampling method. To calculate...
Small cell lung cancer (SCLC) is a subtype of with poor prognosis. In this study, we aimed to build nomogram predict the survival individual SCLC by incorporating significant clinical parameters.The patients were enrolled from First Affiliated Hospital Guangzhou Medical University (GMUFAH) between 2009 and 2013. We identified incorporated independent prognostic factors patients. The predictive accuracy discriminative ability evaluated concordance index (C-index) calibration curve. also...
Abstract Context The significance of an early diagnosis gestational diabetes mellitus (GDM) with oral glucose tolerance test (OGTT) has not been determined. Objective objective this work is to investigate GDM diagnosed by and standard OGTTs determine adverse maternal neonatal outcomes associated diagnosis. Research Design Methods Early Diagnosis Gestational Diabetes Mellitus study a prospective cohort study. Each participant in the underwent 2 OGTTs, OGTT at 18 20 weeks (gws) 24 28 gws....
The problem of missing data, particularly for dichotomous variables, is a common issue in medical research. However, few studies have focused on the imputation methods data and their performance, as well applicability these factors that may affect performance. In arrangement application scenarios, different mechanisms, sample sizes, rates, correlation between value distributions, number variables were considered. We used simulation techniques to establish variety compound scenarios conducted...
BackgroundPostoperative nausea and vomiting (PONV) is a major problem after surgery. Even with double prophylactic therapy including dexamethasone 5-hydroxytryptamine-3 receptor antagonist, the incidence still high in many at-risk patients. Fosaprepitant, neurokinin-1 an effective antiemetic, but its efficacy safety combination antiemetic for preventing PONV remain unclear.MethodsIn this randomised, controlled, double-blind trial, 1154 participants at risk of undergoing laparoscopic...
Abstract Zinc (Zn) is a crucial trace element essential for human growth and development, particularly reproductive health. Previous research has shown decrease in serum zinc concentration with age individuals conditions such as polycystic ovary syndrome (PCOS) diabetes mellitus. However, the specific effects of deficiency on female system, especially ovarian function, are not fully understood. In our study, we observed significant reduction total number follicles mature group. This...
As a clinical precursor to Alzheimer's disease (AD), amnestic mild cognitive impairment (aMCI) bears considerably heightened risk of transitioning AD compared cognitively normal elders. Early prediction whether aMCI will progress is paramount importance, as it can provide pivotal guidance for subsequent interventions in an early and effective manner. A total 107 cases were enrolled their electroencephalogram (EEG) data collected at the time initial diagnosis. During 18-month follow-up...
Understanding the genomic variation in Pekin duck under artificial selection is important for improving utilization of genetic resources. Here, changes were analyzed by using genome resequencing data from 96 individual samples, including 2 conservation populations and 4 breeding with different backgrounds. The population structure, runs homozygosity (ROH), effective number (Ne), other parameters analyzed. showed lower diversity compared to populations. Maple Leaf Cherry Valley retained low...
Smoking is a pivotal modifiable risk factor for lung cancer (LC). Previous studies have indicated that smoking cessation program might be incorporated into the LC screening program. However, effects of and its duration with age at onset (AAO) LC, all-cause mortality, LC-specific mortality remain unclear. We aimed to comprehensively investigate association cessation-related behaviors on AAO mortality. A total 2671 smokers as primary site from UK Biobank were included in this study, 7:3 ratio...
Large hepatocellular carcinoma (HCC) exhibits heterogeneous morphologies and varied responses to treatment. We evaluated outcomes of patients with different large HCC classifications receiving surgical resection (SR) or transarterial chemoembolization plus ablation (TA). Patients ≥ 5 cm SR TA between May 2016 December 2020 at one center were analyzed retrospectively propensity score matching (PSM). Overall survival (OS) progression-free (PFS) the 2 treatment groups compared. Tumors...
Assuming a linear relationship between continuous predictors and outcomes in clinical prediction models is often inappropriate, as true relationships are rare, potentially resulting biased estimates inaccurate conclusions. Our research group addressed single U-shaped independent variable before. Multiple can improve predictive accuracy by capturing nuanced relationships, but they also introduce challenges like increased complexity potential overfitting. This study aims to extend the...
Reproductive disorders in dairy cows represent a significant challenge to the advancement of industry. Pregnancy success is closely related mechanism immune tolerance, with PD-1/PD-L1 signaling pathway playing role regulation, which associated tolerance and pregnancy maintenance. MicroRNAs can regulate pivotal molecules within pathway, physiological activities, disease processes. p65 PD-L1 expression was significantly increased early pregnant uterine epithelium. In contrast, homogeneous...
Acne vulgaris, a very common condition among adolescents, can result in psychological distress, including anxiety and depression. The purpose of this study was to assess the prevalence risk factors acne vulgaris Chinese adolescents. In Zhou Hai district Guangdong Province, 3163 students 10 18 years old were selected from 7 schools. Information collected using self-administrated questionnaIres physician examinations. calculated data. Potential age, gender, diet, skin type, sleeping habits,...
Introduction A diagnosis of gestational diabetes mellitus (GDM) in low-risk pregnant women is based on an oral glucose tolerance test (OGTT) between 24 and 28 weeks. However, there insufficient evidence for why the performed this time period. Moreover, fetus may be exposed to hyperglycaemia prior current testing frame, making earlier administration potentially advantageous. The main purpose present study investigate GDM diagnostic value OGTT at 18–20 results provide scientific insight into...
Immune cell activation in early sepsis is beneficial to clear pathogens, but immune exhaustion during the inflammatory response induces immunosuppression sepsis. Here, we studied relationship between survival status and prognosis of patients.Sepsis patients admitted our hospital with a diagnosis time less than 24 h were recruited. RNA sequencing technologies used study functional alterations various cells peripheral blood mononuclear (PBMCs) from patients. Flow cytometry electron microscopy...
Abstract Background Over 60% of epilepsy patients globally are children, whose early diagnosis and treatment critical for their development can substantially reduce the disease’s burden on both families society. Numerous algorithms automated detection from EEGs have been proposed. Yet, occurrence epileptic seizures during an EEG exam cannot always be guaranteed in clinical practice. Models that exclusively use seizure risk artificially enhanced performance metrics. Therefore, there is a...
<h3>Objectives</h3> Nephrolithiasis (kidney stones) is a common disease with the prevalence that increasing globally. We previously found trimethyltin (TMT), by-product of plastic stabilisers, can inhibit H<sup>+</sup>/K<sup>+</sup> ATPase activity in renal intercalated cells and alter urinary pH, which known risk factor for nephrolithiasis. In this study, we conducted cross-sectional analysis to evaluate impact chronic low level occupational TMT exposure on <h3>Methods</h3> This study...