A5031051410- Animal Nutrition and Physiology
- Genetic and phenotypic traits in livestock
- Livestock and Poultry Management
- Genetic Mapping and Diversity in Plants and Animals
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Animal Genetics and Reproduction
- Cancer-related molecular mechanisms research
- RNA and protein synthesis mechanisms
- melanin and skin pigmentation
- interferon and immune responses
- RNA Research and Splicing
- Genetic diversity and population structure
- Silkworms and Sericulture Research
- Animal Behavior and Reproduction
- Meat and Animal Product Quality
- MicroRNA in disease regulation
- Epigenetics and DNA Methylation
- RNA modifications and cancer
- RNA regulation and disease
- Genomics and Chromatin Dynamics
- Animal Disease Management and Epidemiology
- Genomics and Phylogenetic Studies
- Sperm and Testicular Function
- Animal Virus Infections Studies
- Plant Reproductive Biology
China Agricultural University
2016-2025
State Key Laboratory of Animal Nutrition
2018-2024
Xinjiang Production and Construction Corps
2022-2024
Tarim University
2022-2024
Ministry of Agriculture and Rural Affairs
2021-2024
Washington State University
2019
Poultry Research Institute
2019
Institute of Forest Ecology, Environment and Protection
2014
Chinese Academy of Forestry
2014
Shandong Provincial Institute of Dermatology and Venereology
2011-2012
The genetic determination of eggshell coloration has not been determined in birds. Here we report that the blue is caused by an EAV-HP insertion promotes expression SLCO1B3 gene uterus (shell gland) oviduct chicken. In this study, map location was refined linkage analysis F(2) chicken population, and four candidate genes within interval were subsequently tested for their levels shell gland from blue-shelled non-blue-shelled hens. found to be only one expressed hens but Results a...
Abstract Background The genetic basis of animal domestication remains poorly understood, and systems with substantial phenotypic differences between wild domestic populations are useful for elucidating the adaptation to new environments as well rapid change. Here, we sequenced whole genome 78 individual ducks, from two seven domesticated populations, an average sequencing depth 6.42X per individual. Results Our population demographic analyses indicate a complex history domestication, early...
Abstract Background The prevalence and clinical characteristics of psoriatic arthritis (PsA) in patients with psoriasis vary widely different countries studies on Chinese population are rarely reported. Objective aim this study was to evaluate the PsA a psoriasis. Methods A large cross‐sectional observational conducted our outpatient dermatology department consecutive were evaluated for according Classification Psoriatic (CASPAR) criteria. Demographic medical parameters recorded. Results...
Availability of the complete genome sequence as well high-density SNP genotyping platforms allows genome-wide association studies (GWAS) in chickens. A array containing 57,636 markers was employed herein to identify associated variants underlying egg production and quality traits within two lines chickens, i.e., White Leghorn brown-egg dwarf layers. For each individual, age at first (AFE), weight (FEW), number eggs (EN) from 21 56 weeks were recorded, including (EW), eggshell (ESW), yolk...
Feed contributes to over 60 % of the total production costs in poultry industry. Increasing feed prompt geneticists include intake and efficiency as selection goals breeding programs. In present study, we used an F2 chicken population a genome-wide association study (GWAS) detect potential genetic variants candidate genes associated with daily (FI) efficiency, including residual (RFI) conversion ratio (FCR). A 1534 hens from White Leghorn Dongxiang reciprocal cross were phenotyped for...
Following chicken domestication, diversified breeds were developed by both natural and artificial selection, which led to the accumulation of abundant genetic phenotypic variations, making chickens an ideal research model. To better understand structure under different selection pressures, we genotyped various populations with specific targets, including indigenous, commercial, gamecock, wild ancestral chickens, using 600K SNP array. We analyzed population structure, relationships, run...
Abstract Background Chicken is one of the most numerous and widely distributed species around world, many studies support multiple ancestral origins domestic chickens. The research regarding yellow skin phenotype in chickens (regulated by BCO2 ) likely originating from grey junglefowl serves as crucial evidence for demonstrating However, beyond gene region, much remains unknown about introgression into Therefore, this study, based on whole-genome data 149 samples including 4 wild junglefowls...
The objective of the present study was to evaluate role myofiber characteristics and thickness 2 major muscle membranes, perimysium endomysium, in determining breast meat tenderness chickens. Birds from breeds (White Leghorn a line broiler) were chosen. Chicks sexed wing-banded at hatch grown separate cages single house. Sixty broilers 60 White Leghorns harvested 6 wk age, respectively, whereas another slaughtered 18 age. An equal number males females maintained for each group. Body weight,...
Egg number (EN), egg laying rate (LR) and age at first (AFE) are important production traits related to in poultry industry. To better understand the knowledge of genetic architecture dynamic EN during whole cycle provide precise positions associated variants for EN, LR AFE, records from 21 72 weeks were collected individually 1,534 F2 hens produced by reciprocal crosses between White Leghorn Dongxiang Blue-shelled chicken, their genotypes assayed chicken 600 K Affymetrix high density...
As a major economic trait in chickens, egg weight (EW) receives widespread interests breeding, production and consumption. However, limited information is available for underlying genetic architecture of longitudinal trend EW. Herein, we measured EWs at nine time points from onset laying to 60 week age, conducted comprehensive genome-wide association studies (GWAS) 1,534 F2 hens derived reciprocal crosses between White Leghorn Dongxiang chickens. Egg weights all ages except the first (FEW)...
Heat stress has resulted in great losses poultry production. To address this issue, we systematically analyzed chicken hypothalamus transcriptome responses to thermal using a 44 k Agilent microarray, Hypothalamus samples were collected from control group reared at 25°C, heat-stress treated 34°C for 24 h, and temperature-recovery 25°C h following treatment. We compared the expression profiles between each pair of three groups microarray data. A total 1,967 probe sets found be differentially...
Geese are among the most important poultry species in world. The current generally accepted hypothesis is that European domestic geese originated from greylag (Anser anser), and Chinese have two origins, of which swan cygnoides), Yili goose geese. To explain origin demographic history geese, we selected 14 breeds Europe China wild populations whole genome sequencing data were obtained for 74 samples.Population structure analysis phylogenetic trees showed ancestor except Yili, Analysis...
The quality of poultry eggshells is closely related to the profitability egg production. Eggshell speckles reflect an important trait that influences appearance and customer preference. However, mechanism speckle formation remains poorly understood. In this study, we systematically compared serum immune antioxidant indices hens laying speckled normal eggs. Transcriptome methylome analyses were used elucidate eggshell formation.The results showed seven differentially expressed genes (DEGs)...
Abstract Background Avian pathogenic E. coli (APEC) can cause localized or systemic infections, collectively known as avian colibacillosis, resulting in huge economic losses to poultry industry globally per year. In addition, increasing evidence indicates that long non-coding RNAs (lncRNAs) play a critical role regulating host inflammation response bacterial infection. However, the of lncRNAs APEC infection remains unclear. Results Here, we found 816 differentially expressed (DE) and 1,798...
Plumage color is a characteristic trait of ducks that originates as result natural and artificial selection. As conspicuous phenotypic feature, it breed characteristic. Previous studies have identified some genes associated with the formation black white plumage in ducks. However, on genetic basis underlying red phenotype are limited. Here, genome-wide association analysis (GWAS) selection signal detection (Fst, θπ ratio, cross-population composite likelihood ratio [XP-CLR]) were conducted...
In the late growth stage of commercial Pekin ducks, a significant increase in feed intake and decline body weight gain have been observed, leading to impaired conversion efficiency. To address this issue, we investigated alterations production performance, blood biochemical indices, ileum tissue architecture, microbial community structure ducks. The primary objective was provide robust data supporting improvement meat duck efficiency during (28-42-days-old). Forty 28-day-old ducks were...
Understanding the genomic variation in Pekin duck under artificial selection is important for improving utilization of genetic resources. Here, changes were analyzed by using genome resequencing data from 96 individual samples, including 2 conservation populations and 4 breeding with different backgrounds. The population structure, runs homozygosity (ROH), effective number (Ne), other parameters analyzed. showed lower diversity compared to populations. Maple Leaf Cherry Valley retained low...
Abstract Introduction The blue peafowl (Pavo cristatus) and the green muticus) have garnered significant public affection due to their stunning appearance, although is currently endangered. causative mutation that causes leucistic plumage of (also called white peafowl) remains unknown. Results In this study, we generated a chromosome-level reference genome with contig N50 30.6 Mb, including autosomes, Z W sex chromosomes, complete mitochondria DNA sequence. Data from 77 whole genomes, 76...
DNA silver staining is widely used to detect fragment in polyacrylamide gel with high sensitivity. Conventional procedures of the involve several steps, which take about 40 min 2 h total. To improve efficiency staining, a more efficient protocol developed this study. The procedure comprises only four steps including impregnating, rinsing, developing, and stopping, could be completed within 20 min. Nitric acid ethanol silver-impregnation step new eliminates need for prior treatment gels...
Blue-shelled eggs are gaining popularity as the consumption demand diversifies in some countries. This study was carried out to investigate laying performance and egg quality of blue-shelled layers well effects different housing systems on production traits. One thousand pullets from Dongxiang were divided into 2 even groups kept (outdoor vs. cage). Daily recorded 20 60 wk age. External internal traits examined at 26, 34, 42, 50 wk. Yolk cholesterol concentration whole content measured 40...
Marek’s disease is a lymphoproliferative neoplastic of the chicken, which poses serious threat to poultry health. virus (MDV)-induced T-cell lymphoma also an excellent biomedical model for neoplasia research. Recently, miRNAs have been demonstrated play crucial roles in mediating transformation. To investigate host miRNA expression profiles tumor transformation phase MDV infection, we performed deep sequencing two MDV-infected samples (tumorous spleen and MD from liver), non-infected...