A5100761399- Thermography and Photoacoustic Techniques
- Regulation of Appetite and Obesity
- Adipose Tissue and Metabolism
- Fatty Acid Research and Health
- Biochemical Analysis and Sensing Techniques
- Adipokines, Inflammation, and Metabolic Diseases
- Diet, Metabolism, and Disease
- Optical measurement and interference techniques
- Diabetes Treatment and Management
- Fire effects on concrete materials
- Advanced Measurement and Detection Methods
- Laser Material Processing Techniques
- Structural Health Monitoring Techniques
- Advanced Sensor Technologies Research
- Neuropeptides and Animal Physiology
- Nuclear Receptors and Signaling
- Surface Roughness and Optical Measurements
- Radiative Heat Transfer Studies
- Diabetic Foot Ulcer Assessment and Management
- Image and Object Detection Techniques
- Mechanical Behavior of Composites
- Textile materials and evaluations
- Ultrasonics and Acoustic Wave Propagation
- Sparse and Compressive Sensing Techniques
- Apelin-related biomedical research
Second Affiliated Hospital of Zhejiang University
2021-2024
Zhejiang University
2024
First People's Hospital of Foshan
2023
China Aerodynamics Research and Development Center
2020-2022
Yangzhou University
2017
Horological Research Institute of Light Industry
2017
Peking University
2010-2014
Abstract Background Eicosapentaenoic acid (EPA) and docosahexaenoic (DHA) have been suggested to prevent the development of metabolic disorders. However, their individual role in treating hyperglycemia mechanism action regarding gut microbiome metabolome context diabetes remain unclear. Results Supplementation DHA EPA attenuated insulin resistance without changing body weight db/db mice while ameliorative effect appeared be more pronounced for EPA. DHA/EPA supplementation reduced abundance...
Significance The peripheral effect of ghrelin on energy metabolism has been controversial. Our study demonstrates a direct to increase de novo lipogenesis in hepatocytes. Moreover, we define mammalian target rapamycin (mTOR)-peroxisome proliferator-activated receptor-γ (PPARγ) signaling pathway as the intracellular is mediated by interaction between raptor and PPARγ. identifies previously unidentified treat NFALD via targeting hepatic receptor/mTOR/PPARγ.
ELABELA (ELA), a recently discovered peptide, is highly expressed in adult kidneys and the endothelium system. It has been identified as novel endogenous ligand for apelin receptor (APJ). This study aims to investigate role of ELA diabetic glomerular endothelial pyroptosis its underlying mechanism. Initially, significant decrease mRNA levels was observed renal cortex db/db mice high glucose-treated cells (GECs). also found that deficiency ELA+/- significantly accelerated injury, shown by...
Pediatric allergic rhinoconjunctivitis has become a public concern with an increasing incidence year by year. Conventional subcutaneous immunotherapy (SCIT) long treatment time, high cost and poor compliance. The novel significantly shortens the course of directly injecting allergens into cervical lymph nodes, which can perform faster clinical benefits to children.By comparing SCIT, this study aimed evaluate long-term efficacy safety intra-cervical lymphatic (ICLIT).This is prospective...
Abstract The line laser scanning thermography was applied for the defect detection and evaluation of composite material in this work, which carried out by following procedures. First, a novel contrast enhancement method homomorphic technology proposed validated case study. Then, specimen containing 12 prefabricated defects detected using obtained thermal image sequence changeable temperature were analyzed. Finally, area via such processing as based on method, threshold segmentation...
Abstract Background & Aims Ghrelin, a gut hormone with pleiotropic effects, may act as protective signal in parenchymal cells. We investigated the effects of ghrelin on hepatocytes after ischaemia/reperfusion (I/R). Methods Hepatic injury was assessed by measurement plasma alanine aminotransferase ( ALT ) and lactate dehydrogenase LDH ), histological analysis, TUNEL assay. Effects exogenous receptor gene deletion I/R induced liver were evaluated. Results Ischaemia/reperfusion profound to...
The low-velocity impact response and infrared radiation characteristics of composites have rarely been focused on simultaneously. This study aims to investigate the glass fiber reinforced thermoplastic polypropylene carbon thermosetting epoxy resin laminates wildly used in aircraft industry. tests were conducted at five energy levels. Characterization parameters such as load, displacement, absorbed measured. damage evolution modes analyzed through active passive thermography, ultrasonic...
Abstract Aim To investigate the association between fish oil supplementation and subsequent risk of chronic kidney disease (CKD) among patients with diabetes, further evaluate mediation effect typical glycolipid inflammatory biomarkers. Methods In total, 24 497 diabetes from UK Biobank were included. Cox proportional hazards regression models used to estimate hazard ratios (HRs) 95% confidence intervals (CIs) for CKD risk, rate advancement period was calculated quantify communicate impact...
Within the rapidly evolving panorama of virtual financial system, function training in fostering innovation and entrepreneurship has become more vital. This study aims to explore how big records analysis digital sharing techniques can be leveraged complement schooling. The observation is grounded within context economy generation, characterised with aid proliferation technologies exponential boom facts. middle objective research instructional desirable thru utility large analytics sharing,...
Nonlinear vibration plays a vital role in ultrasonic infrared thermography testing due to contact-collision effect between horn and sample, the effects of contact roughness sample mass on characteristics horn-sample system are deeply investigated this paper. A two-degree-of-freedom dynamic model based GW is proposed for exploring system. Then, calculated under different mass. The results demonstrate that does not influence characteristic horn, but there mainly 2f 3f except first harmonic f...
Nesfatin‐1 is an 82‐amino acid anorexigenic peptide which also contributes to the regulation of glucose homeostasis. Mechanisms by nesfatin‐1 modulates metabolism remain largely unknown. Our studies showed that chronic infusion a subcutaneous micro‐pump for two weeks significantly improves tolerance in both lean and high fat diet induced obese mice, while central administration demonstrated no effect. Plasma insulin increased after normal chow further increment was observed mice. Analysis...
A novel thermographic methodology is proposed in this work to predict damage evolution of impacted CFRP laminates under compression-compression fatigue loading based on inverted weibull model. To goal, the model firstly mathematically proposed. Then, several specimens are subjected impact testing, followed by testing and monitored infrared thermography. Afterwards, thermal image surface temperature analyzed. Finally, taking as variables, introduced evolution. The obtained results show that...
Knee joint is very important for human activities, and its disease diagnosis treatment are usually carried out by magnetic resonance technology. The residual image of knee easy to cause misjudgement in the medical field. In this paper, an iterative threshold segmentation algorithm applied segment recognize MR images. results show that can effectively remove images tumor injuries. research has certain guidance reference significance clinical joint.
The role of gastric mTOR signaling in ghrelin production and food intake was examined this study. Here we showed the reciprocal relationship during changes energy status. activity down‐regulated, while preproghrelin circulating total acyl were increased by fasting. In db/db mice, enhanced, whereas anc decreased. Inhibition rapamycin stimulated expression mRNA, plasma both wildtype mice. Activation L‐leucine decreased level ghrelin. Ghrelin receptor antagonist D‐Lys3‐growth hormone releasing...
In order to investigate the vibration characteristics of object in nondestructive test using thermosonics, device for measuring micro-displacement was built based on laser displacement sensor and ultrasonic excitation equipment.On this basis, measured under condition loading with frequency 40 kHz non-ultrasonic respectively.Then, analysis spectrum obtained by carried out.The results show that there is fundamental as well high-order harmonic frequencies, which confirms existence acoustic...
Palmitoylation cycling involves successive addition and removal of lipid from proteins to regulate cell structure membrane interactions. Cycling requires depalmitoylation, mediated mostly by the enzyme acyl-protein thioesterase 1 (APT1). To test hypothesis that depalmitoylation is critical for normal glucose metabolism, we generated global islet-specific (using tamoxifen-inducible Pdx1 Cre) APT1 knockout mice. Both models on a chow diet had enhanced tolerance due increased insulin secretion....
In this work, the constrained least square filter is introduced to remove noise of medical ankle image. Firstly, algorithm principle regarding studied. On basis, a image with Gaussian processed based on and low pass filter. Finally, peak signal-to-noise ratio, PSNR, quantitatively estimate post-processing quality. The obtained results show that PSNR by larger than filter, which validates can effectively.