Luise Borch

ORCID: 0000-0003-1054-0601
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About
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Research Areas
  • Urinary Bladder and Prostate Research
  • Pelvic floor disorders treatments
  • Urological Disorders and Treatments
  • Urinary Tract Infections Management
  • Pediatric Urology and Nephrology Studies
  • COVID-19 Clinical Research Studies
  • Orthopedic Infections and Treatments
  • Diabetes Management and Research
  • Bladder and Urothelial Cancer Treatments
  • COVID-19 and Mental Health
  • Diabetes and associated disorders
  • Metabolism and Genetic Disorders
  • Long-Term Effects of COVID-19
  • Congenital gastrointestinal and neural anomalies
  • Blood groups and transfusion
  • Mechanical Circulatory Support Devices
  • Gastrointestinal motility and disorders
  • Pharmaceutical studies and practices
  • Folate and B Vitamins Research
  • Coronary Artery Anomalies
  • Respiratory viral infections research
  • Streptococcal Infections and Treatments
  • Renal and related cancers
  • COVID-19 Impact on Reproduction
  • Neonatal Health and Biochemistry

Regionshospitalet Herning
2021-2024

Glostrup Hospital
2021-2024

Aarhus University Hospital
2011-2023

Regional Hospital West Jutland
2020-2022

Aalborg University Hospital
2017

Aarhus University
2012

Abstract Most children have a mild course of acute COVID-19. Only few mainly non-controlled studies with small sample size evaluated long-term recovery from SARS-CoV-2 infection in children. The aim this study was to evaluate symptoms and duration ‘long COVID’ A nationwide cohort 37,522 aged 0–17 years RT-PCR verified (response rate 44.9%) control group 78,037 21.3%). An electronic questionnaire sent all March 24th until May 9th, 2021. Symptoms lasting > 4 weeks were common among both...

10.1007/s00431-021-04345-z article EN cc-by European Journal of Pediatrics 2022-01-09

The prevalence of newborns with congenital adrenal hyperplasia (CAH) detected by neonatal screening is well-described, but data including patients diagnosed later in life are extremely limited. This study aimed to describe diagnostic trends for all CAH Denmark.A nationwide population-based registry medical record review.We identified 462 (290 females) any form CAH. combined was 15.1 (95% confidence interval [CI]: 12.3-16.1) and 9.0 (CI: 7.6-10.4) per 100,000 newborn females males. There a...

10.1016/j.lanepe.2023.100598 article EN cc-by-nc-nd The Lancet Regional Health - Europe 2023-02-27

To investigate the effect of treating defecation problems on urinary incontinence in children suffering from combined bladder and bowel dysfunction (BBD).We established a clinical database medical records all referred to gastroenterology outpatient clinics with BBD. The following variables were extracted: symptoms constipation, faecal incontinence, age at onset symptoms, treatment, including duration response. All went through same treatment protocol. Faecal disorders treated primarily once...

10.1111/apa.12158 article EN Acta Paediatrica 2013-02-01

Background: Treatment of type 1 diabetes mellitus (T1DM) has become increasingly technical with rapid developments in integration pumps and sensors to regulate insulin dosage, patient-initiated solutions as open-source automated delivery (OS-AID) systems, have gained popularity people diabetes. Studies shown increased glycemic control mental wellbeing users OS-AID systems. The aim this study was estimate the prevalence, effect on metabolic control, risk, everyday life for their parents...

10.1089/dia.2023.0412 article EN cc-by Diabetes Technology & Therapeutics 2024-02-22

In a third of all children with monosymptomatic nocturnal enuresis their condition is refractory to first line treatments. Transcutaneous electrical nerve stimulation has been documented be efficacious in daytime incontinence. We investigated the effect transcutaneous without polyuria.Children (3 or more wet nights per week) and no polyuria were randomized treatment active sham involving 1-hour sessions twice daily for 10 weeks double-blind design.Of 52 included study 47 completed (mean age...

10.1016/j.juro.2017.04.082 article EN The Journal of Urology 2017-07-23

No AccessJournal of UrologyPediatric Urology1 Aug 2017Transcutaneous Electrical Nerve Stimulation Combined with Oxybutynin is Superior to Monotherapy in Children Urge Incontinence: A Randomized, Placebo Controlled Study Luise Borch, Soeren Hagstroem, Konstantinos Kamperis, C.V. Siggaard, and Rittig BorchLuise Borch More articles by this author , HagstroemSoeren Hagstroem KamperisKonstantinos Kamperis SiggaardC.V. Siggaard RittigSoeren View All Author...

10.1016/j.juro.2017.03.117 article EN The Journal of Urology 2017-03-19

To evaluate the immediate effect on natural fill urodynamic parameters and bladder function during transcutaneous electrical nerve stimulation (TENS) in children with overactive (OAB) daytime urinary incontinence (DUI).In this double-blind, placebo-controlled study, 24 severe OAB DUI (mean age 8.5 ± 1.2 years) underwent 48-h urodynamics. After h of baseline investigation, were randomized to either active continuous TENS (n = 12) or placebo over sacral S2-S3 outflow. The recordings analyzed...

10.1002/nau.23179 article EN Neurourology and Urodynamics 2016-11-21

Acute pyelonephritis is one of the most common bacterial infections in childhood. This potentially serious condition can lead to renal scarring, loss kidney function and hypertension. The aim this study was identify risk factors associated with children without or urinary tract abnormalities.Medical records aged 4-18 diagnosed 1st time from 2016 2021 were retrospectively analysed. Children abnormal ultrasound excluded. In addition demographic data, information on bladder bowel extracted...

10.1111/apa.16608 article EN cc-by-nc-nd Acta Paediatrica 2022-11-27

Abstract Background Nocturnal enuresis (NE) is a common disease with multiple pathogenic mechanisms. This study aimed to compare levels of metabolites and proteins between wet dry nights in urine samples from children monosymptomatic NE (MNE). Methods Ten boys MNE nocturnal polyuria (age: 7.6 ± 1.3 years) collected their total nighttime production during night. Untargeted metabolomics proteomics were performed on the by liquid chromatography coupled high-mass accuracy tandem mass...

10.1007/s00467-023-05963-5 article EN cc-by Pediatric Nephrology 2023-05-04

Carnitine palmitoyl transferase (CPT) 1 A deficiency is a rare disorder of hepatic long-chain fatty acid oxidation. CPT1 included in newborn screening programs number countries to allow presymptomatic detection and early treatment affected patients.We present case CPT1A detected through Denmark with diagnostic levels carnitine acylcarnitines the initial dried blood spot. Levels plasma-free follow-up samples were normal, but reverted when patient developed clinical symptoms at age 8 months....

10.1007/8904_2011_35 article EN JIMD Reports 2011-01-01

To the Editors: Coronavirus disease 2019 (COVID-19) is a mostly mild in children and adolescents. Nevertheless, publications have frequently focused on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) hospitalized children.1,2 our knowledge, no studies estimated proportion of with SARS-CoV-2 needing hospitalization, as data nonhospitalized rarely available.3 We performed Danish population-based cohort study all due to COVID-19 between March 12 September 30, 2020. The took place...

10.1097/inf.0000000000003127 article EN The Pediatric Infectious Disease Journal 2021-05-10

Abstract Introduction Giggle incontinence (GI) is a rare form of urinary that occurs during or immediately after laughing due to involuntary and complete bladder emptying. Few studies in the literature report methylphenidate can be effective treatment this condition. Objective The aim study characterize children with GI evaluate their response methylphenidate, as well describe duration, dosage relapse rates discontinuation medication, side effects. Methods Medical records 48‐h...

10.1002/nau.25232 article EN cc-by-nc-nd Neurourology and Urodynamics 2023-06-28

Abstract Background: Most children have a mild course of acute COVID-19, but only few mainly non-controlled studies with small sample size, evaluated the long-term recovery from SARS-CoV-2 infection in (‘long COVID’). Methods: We conducted nationwide cohort study 37,522 age 0-17 years RT-PCR verified and control group 78,037 randomly selected children. An electronic questionnaire was sent to both groups March 24th until May 9th 2021. Results: Long COVID symptoms were reported by 12-51%...

10.21203/rs.3.rs-839948/v1 preprint EN cc-by Research Square (Research Square) 2021-09-27

Objectives: Mean differences in HbA 1c across centers are well established, but less understood.The aim was to assess whether patient case-mix can explain the variation mean between pediatric diabetes Denmark.The association , frequency of blood glucose monitoring (BGM), treatment modality, and center visits investigated. ResearchDesign Methods: This longitudinal nationwide study included 3,866 Danish children with type 1 from 2013-2017 (n= 12,708 child-year observations) 16 different...

10.1111/pedi.13284 article EN Pediatric Diabetes 2021-11-12

Abstract The objective of this study is to examine the effect discontinuing wearing protective garments (absorbent pyjama pants — APP) in children with severe childhood nocturnal enuresis (NE). employs a multicenter, parallel, randomized controlled trial. Following 4-week run-in period, participants were randomly allocated 2:1 group allocation discontinue or continue using APP. research was conducted across seven European pediatric incontinence centers. included treatment-naïve aged 4–8...

10.1007/s00431-024-05502-w article EN cc-by European Journal of Pediatrics 2024-03-12

<sec> <title>BACKGROUND</title> To the best of our knowledge, no studies have investigated withdrawal strategy pharmacological treatment with solifenacin and/or mirabegron in children diagnosed urinary incontinence that achieved continence on pharmacotherapy. </sec> <title>OBJECTIVE</title> The primary objective is to investigate if abrupt versus gradual pharmacotherapy (solifenacin mirabegron) influences risk recurrence incontinence. <title>METHODS</title> Children aged 5-14 years...

10.2196/preprints.63226 preprint EN cc-by 2024-06-13

<sec> <title>BACKGROUND</title> According to International Children’s Continence Society (ICCS), first-line treatment of children with daytime urinary incontinence is standard urotherapy, eventually followed by pharmacotherapy anticholinergics. The effect medical sparsely investigated and primarily in non-randomized trials. </sec> <title>OBJECTIVE</title> primary objective evaluate if (1) combination therapy solifenacin mirabegron low doses superior monotherapy high dose (2) among aged 5 14...

10.2196/preprints.63588 preprint EN cc-by 2024-06-24

Children with bone and joint infections are traditionally treated intravenous antibiotics for 3-10 days, followed by oral antibiotics. Oral-only treatment has not been tested in randomised trials. (3 months to 18 years) will be 1:1 the experimental group receiving high-dose control a shift both groups standard after clinical paraclinical improvement. need of acute surgery or systemic features requiring therapy, including septic shock, excluded. The primary outcome is defined as normal...

10.1136/bmjopen-2023-072622 article EN cc-by-nc BMJ Open 2023-06-01

Multicystic dysplastic kidney (MCDK) and unilateral renal agenesis (URA) are the most common reasons for a congenital solitary functioning (SFK). We aimed to assess presence of abnormalities in SFK evaluate function using chrome EDTA (CrEDTA) measurements.We retrospectively reviewed medical records 154 children with MCDK URA period from 2005 2022 analyze results ultrasound scans CrEDTA glomerular filtration rate (GFR) examinations.Of due (62%) or (38%), on were found 13 (8%). The...

10.1016/j.jpurol.2023.05.019 article EN cc-by Journal of Pediatric Urology 2023-06-03
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