A5101652997- Biofuel production and bioconversion
- Lignin and Wood Chemistry
- Bioenergy crop production and management
- Plant Gene Expression Analysis
- Wood Treatment and Properties
- Renal and related cancers
- Tree Root and Stability Studies
- CRISPR and Genetic Engineering
- Pluripotent Stem Cells Research
- Fungal and yeast genetics research
- Forest Biomass Utilization and Management
- Abdominal Surgery and Complications
- High-Temperature Coating Behaviors
- Enzyme-mediated dye degradation
- Plant and Fungal Interactions Research
- Plant Reproductive Biology
- Solid State Laser Technologies
- Advanced Cellulose Research Studies
- Surgical Simulation and Training
- Gastrointestinal disorders and treatments
- Research in Cotton Cultivation
- Minimally Invasive Surgical Techniques
- Glass properties and applications
North Carolina State University
2016-2020
InterAmerican University of Puerto Rico
2020
North Central State College
2020
University of Minnesota
2018-2019
National Taiwan University
2019
University of Notre Dame
2011
A multi-omics quantitative integrative analysis of lignin biosynthesis can advance the strategic engineering wood for timber, pulp, and biofuels. Lignin is polymerized from three monomers (monolignols) produced by a grid-like pathway. The pathway in formation Populus trichocarpa has at least 21 genes, encoding enzymes that mediate 37 reactions on 24 metabolites, leading to affecting properties. We perturb these genes integrate transcriptomic, proteomic, fluxomic phenomic data 221 lines...
Polycrystalline ceramics offer a number of advantages relative to single crystal materials such as lower processing temperatures, improved mechanical properties, and higher doping levels with more uniform distribution dopants for laser performance. Ceramic YAG (Y<sub>3</sub>Al<sub>5</sub>O<sub>12</sub>) rare earth sesquioxide (RE<sub>2</sub>O<sub>3</sub>) fibers promise enable high power devices via thermal conductivity allowable dopant concentration; however, these are not currently...
Transgenic Populus trichocarpa wood was compared to the corresponding wild-type material. The static modulus of elasticity in three-point bending measured and chemical composition among specimens were compared, including glucose, xylose, lignin contents as well S/G ratio. Changes composition, created by genetic manipulations biosynthetic pathway, affect mechanical properties young small-diameter transgenic trees. There are indications that a decrease content causes severe reductions...
Vessel and fiber properties, diameter growth, chemical compositions were investigated for transgenic Populus trichocarpa (black cottonwood) trees harvested after six months of growth in a greenhouse. Genetic modifications cinnamyl alcohol dehydrogenase (CAD), cinnamate 3-hydroxylase (C3H), or 4-hydroxylase (C4H), which resulted modified lignin composition content, changed the syringyl-to-guaiacyl ratio. Comparing genetic groups to wild-type as control, with reduced content showed different...
Intra-abdominal organ and vascular injuries during laparoscopic trocar placement remain a significant cause for surgical complications procedures. These can arise if the surgeon deviates from proper axis, requiring additional applied force to obliquely traverse abdominal wall. This increase in application increases risk of internal vessel damage immediately after entrance peritoneal cavity. To mitigate this risk, our group designed that provides real-time feedback deviation insertion force,...
Traditional breeding methods are often constrained by the reproductive cycles of tree species and difficulty in achieving significant improvements to complex traits; therefore, genetic manipulation traits such as wood properties has potential resolve those issues. The objectives this study were analyze MOE, MOR, physical anatomical 2- 3-yr-old field-grown transgenic Pinus taeda trees modified for increased density. This investigation consisted a total 55 sample two separate experiments....
Fungal pretreatment of Populus trichocarpa wood genetically modified to reduce lignin and alter chemistry is investigated for its effectiveness as an alternative common methods. The goal this work improve biomass utilization biofuel biochemical applications by increasing sugar release. Sugar release after enzymatic hydrolysis was measured various pretreatments (including wood-rot fungus, hot water, dilute acid). In the wildtype, in constructs downregulated PAL, 4CL, C3H, fungal resulted...
Wood processing is often performed at elevated temperatures under moisture-saturated conditions; therefore, it important to understand the impact of lignin content and chemical structure on thermo-mechanical properties wood. In this study, genetically modified Populus trichocarpa wood specimens with down-regulated cinnamyl alcohol dehydrogenase, cinnamate 3-hydroxylase, 4-hydroxylase altered contents and/or structures were utilized probe relationship between content, monomer composition,...
Fungal pretreatment of Populus trichocarpa wood genetically modified to reduce lignin and alter chemistry is investigated for its effectiveness as an alternative common methods. The goal this work improve biomass utilization biofuel biochemical applications by increasing sugar release. Sugar release after enzymatic hydrolysis was measured various pretreatments (including wood-rot fungus, hot water, dilute acid). In the wildtype, in constructs downregulated PAL, 4CL, C3H, fungal resulted...