A5100351498- Amino Acid Enzymes and Metabolism
- Sulfur Compounds in Biology
- Glutathione Transferases and Polymorphisms
- Cancer, Lipids, and Metabolism
- Lung Cancer Diagnosis and Treatment
- Genomics, phytochemicals, and oxidative stress
- Lung Cancer Research Studies
- Epigenetics and DNA Methylation
- Lung Cancer Treatments and Mutations
- Photodynamic Therapy Research Studies
- Magnesium in Health and Disease
- Bone health and treatments
- Alkaline Phosphatase Research Studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Enzyme Catalysis and Immobilization
- Advanced Nanomaterials in Catalysis
- Inflammasome and immune disorders
- Nanoplatforms for cancer theranostics
- Parathyroid Disorders and Treatments
- Flavonoids in Medical Research
- Carbon Dioxide Capture Technologies
- Metabolomics and Mass Spectrometry Studies
- COVID-19 Clinical Research Studies
- Genetics and Neurodevelopmental Disorders
- Inflammatory mediators and NSAID effects
Tongji University
2010-2024
Shanghai Tenth People's Hospital
2012-2024
National Engineering Research Center for Wheat
2024
Hebei Agricultural University
2024
Shanghai Public Health Clinical Center
2023
Nanjing Tech University
2022
Henan University
2019-2021
Kunming Institute of Zoology
2013
University of Warwick
2013
Chinese Academy of Sciences
2013
The present study aimed to provide data support the association between cystathionine‑γ‑lyase (CSE) and breast cancer metastasis. Reverse transcription‑quantitative polymerase chain reaction, immunohistochemistry western blot analysis were used detect mRNA protein expression levels of CSE in human tissues cells. MTS 5‑ethynyl‑2'‑deoxyuridine assays assess cell viability proliferation. Scratch wound Transwell conducted determine migration invasion. In addition, hydrogen sulfide determination...
There is a lack of evidence to support consensus on whether surgery or radiotherapy optimal for elderly very patients with early-stage non-small cell lung cancer (NSCLC). We aimed assess the impact survival in (≥70 years) and (≥80 NSCLC.
There is no effective treatment for acute lung injury (ALI) at present. Some studies have reported the anti-inflammatory effect of Ejiao, but study has addressed underlying action mechanism. In this study, CCK8 assay displayed Ejiao had a protective against LPS-elicited inflammatory epithelial Beas 2B cells (LILEB cells). treated with LPS and were challenged NFκB inhibitor Bay11-7082 ROS scavenger N-acetyl cysteine (NAC) alone in combination. The results qRT-PCR, Western blotting...
Glutamate dehydrogenase (GDH) has been shown to play a regulatory role in insulin secretion by pancreatic β-cells. The most compelling evidence of this comes from features the hyperinsulism/hyperammonemia (HI/HA) syndrome where dominant mutation causes loss inhibition GTP, and studies that link leucine (and its analogue BCH) activation GDH stimulation secretion. This suggests may represent new novel drug target control variety disorders. Recently we demonstrated subset green tea polyphenols...
As an antioxidant,
Lung cancer is the most commonly diagnosed and leading cause of death worldwide. Amygdalin, a natural compound distributed in plants Rosaceae species, owns anticancer activity, less side effects, wide source, relatively low price. Although apoptosis central process activated by amygdalin cells, underlying molecular mechanisms through which induces lung cells remain poorly understood. In this research work, could suppress proliferation A549 PC9 CCK8 assay. Amygdalin significantly promoted...
As a necessary sulfhydryl amino acid, L-cysteine (L-Cys) maintains many physiological functions in the biological system. However, abnormal L-Cys levels can cause variety of diseases. In our work, highly sensitive and selective assay has been developed for sensing using morphological transformation silver-based materials induced by Cr3+. this system, Cr3+ could etch silver nanoflakes into nanoparticles, accompanied change absorbance, which decreases at 395 nm, creates new peak 538 keeps...
Multisystem inflammatory syndrome adult type (MIS-A) is a rare of post-acute COVID-19 which more frequently occurred in younger population. Here we present 78-year-old Chinese female, the oldest case reported, diagnosed with MIS-A who had severe SARS-CoV-2 infection. She was and experienced an unexpected sudden hemodynamic collapse recovery period within three weeks. Her platelet count sharply dropped, accompanied sustained cardiac, kidney liver injury. according to criteria established by...
Adsorption equilibrium data for pure carbon dioxide and ethane on STH-2 graphitized black were measured by a volumetric method. The experiments carried out over the temperature range (253.2 to 303.2) K pressure (0 4) MPa. relative p/p0 adsorption amount n have been adopted express isotherms, experimental present generalized isotherm research range. On basis of this isotherm, method predicting gas equilibria was explored. prediction accuracy is satisfactory. In addition, analysis BET equation...
We aimed to evaluate the prognostic value of stage IIIB non-small-cell (NSCLC) lung cancer patients and construct a nomogram effectively predict their overall survival (OS).In total, 4323 with NSCLC diagnosed between 1975 2018 were selected from Surveillance, Epidemiology, End Results (SEER) database. Multiple factors combined for predicting OS NSCLC. The discrimination calibration evaluated by C-indexes curves. was predictive ability using receiver operating characteristic (ROC) curves,...
Inspired by biocatalytic retrosynthesis, a multienzyme cascade system containing alcohol dehydrogenase, flavin-dependent halogenase and flavin reductase was developed for the synthesis of several halogenated indoles starting from amino alcohol. This redox-neutral not only omitted co-substrate nicotinamide cofactor (NADH) regeneration but also showed relatively higher conversion chemoselectivity compared with individual biotransformation. Artificial (BNAH) employed to replace NADH simplifying...
DHEA is a steroid secreted by gonads, adrenal cortex, brain, and gastrointestinal tract. In cell experiments, animal human the anti-obesity, anti-atherosclerosis, anti-cancer, memory-enhancing effects of have been verified, but its specific mechanism still unclear. Altered mitochondrial dynamics can lead to dysfunction, which closely related many diseases, especially cancer aging. This study was investigate whether inhibits lung adenocarcinoma through pathway molecular mechanism. this study,...