A5059556726- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Mycotoxins in Agriculture and Food
- Indoor Air Quality and Microbial Exposure
- Carcinogens and Genotoxicity Assessment
- Pesticide Exposure and Toxicity
- Glutathione Transferases and Polymorphisms
- Energy and Environment Impacts
- Occupational exposure and asthma
- Effects and risks of endocrine disrupting chemicals
- Hepatitis C virus research
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Toxic Organic Pollutants Impact
- Global Health Care Issues
- Immunotoxicology and immune responses
- Heavy Metal Exposure and Toxicity
- Human Health and Disease
- Listeria monocytogenes in Food Safety
- Antifungal resistance and susceptibility
- Chromium effects and bioremediation
- Pharmacogenetics and Drug Metabolism
- Viral Infections and Outbreaks Research
- Child Nutrition and Water Access
- Parasites and Host Interactions
- Essential Oils and Antimicrobial Activity
National Research Centre
2015-2024
Environmental Health
2022-2024
Guy's and St Thomas' NHS Foundation Trust
2023
St. Thomas Hospital
2023
St Thomas' Hospital
2023
University of Technology - Iraq
2022
Cairo University
2020
National Water Research Center
2010-2020
Egypt, located in the Middle East and North Africa region, is considered to be a potential hot-spot of climate change where warming increase frequency extreme temperatures could occur faster than at global scale. Precipitation also expected decrease region. In this work, our aim quantify past future temperature precipitation trends 8 locations selected for being representative variety Egyptian climates. For period (1950–2017), we show that decadal derived from analysis assimilated...
Background:Epidemiological studies have demonstrated that serum aflatoxin B1 (AFB1) is a hepatocarcinogenic mycotoxin and contributor to the high rate of hepatocellular carcinoma (HCC). The prevalence liver cancer in Egypt particularly worrisome. In registry-based analysis occupational risk for HCC, significant excesses were observed especially grain mill workers.Objective:The aim this study was assess hepatic carcinogenicity AFB1 wheat handlers.Methods:Serum AFB1/albumin (AFB1/Alb),...
Workers in secondary aluminum production plants are occupationally exposed to polycyclic aromatic hydrocarbons (PAHs). We aimed monitor the concentrations of PAHs air and serum workers at two plants. also investigated potential risk lung cancer development among with emphasis on role A1AT mutation APEX1 gene polymorphisms.This study included 177 from administrative departments lines. Blood samples were obtained for estimation benzo(a)pyrene diol epoxide albumin adduct (BPDE-Alb adduct),...
Dietary control of classic phenylketonuria (PKU) needs restriction natural proteins; adequate protein intake is achieved by adding low phenylalanine (phe) formulae. The adequacy this diet for normal bone mineralization had not been sufficiently evaluated. Our aim was to evaluate and follow up mineral density (BMD) in children adolescents with PKU within a 2-year time interval assess the restricted search possible relationship between BMD, dietary blood concentrations.Thirty-two patients...
Objective: The present work aimed to investigate the relationship between occupational exposure airborne molds, serum aflatoxin B 1 (AFB ), and liver enzymes of workers handling wheat flour. Methods: study included 90 bakers, 100 flour milling workers, controls with no dust. Workplace aspects such as temperature relative humidity were measured. Airborne fungi collected identified. In all subjects included, levels AFB , albumin (Alb), aspartate aminotransferase (AST), alanine (ALT), alkaline...
The Essential oil (EO) of Nigella sativa (black cumin) was extracted from the crude and volatile constituents were characterized using gas chromatographic analysis. EO formulated in water-based microemulsion system its antibacterial activity against six pathogenic bacteria evaluated agar well diffusion method. This compared with two other known biologically active natural synthetic antimicrobials namely eugenol Ceftriaxone(®). Results showed that N. highly effective S. aureus, B. cereus...
Cytochrome P450 CYP1A1 helps detoxify the potential carcinogens in tobacco smoke, it was reported that polymorphisms coding gene result variation expression and activity levels which alter metabolism clearance of therefore modify cancer risk. In this work, we aimed to identify associated with lung Egyptian population examine interaction effect Tobacco smoking modulating disease A case–control study conducted on 150 unrelated patients control subjects. Genomic DNA extracted sequencing...
BACKGROUND: Annona muricata (Soursop) has an antimicrobial activity toward various pathogenic microorganisms which support its ethnomedicinal for the treatment of many infectious diseases.
 AIM: Aim present study to evaluate relation between activities terpenoids extracted from different soursop parts with isolated endophytic fungi.
 METHODS: Endophytic fungal species pulp and peel fruit along those seeds were isolated. Salkowski test was used qualitative screening in plant...
Abstract Background In a study of textile workers, the effects occupational exposure to cotton dust—with possible aflatoxin—on levels some liver tumor biomarkers were explored. Methods The included 58 workers and 64 controls. Skin prick tests, urinary Aflatoxin M1 (AFM1) (alpha‐fetoprotein (AFP), alpha‐ L ‐fucosidase (AFU), insulin‐like growth factors (IGF‐1) measured. Results Positive reactants Aspergillus niger , flavus dust significantly higher in pre‐spinning (14.3%, 28.6%, respectively)...
The textile industry is the second risk factor for bladder cancer, after smoking. Previous studies focused on impact of exposure to high concentrations carcinogenic chemicals in dyeing elevation cancer biomarkers. This study aimed evaluate air pollutants a factory and investigate its role serum 25-hydroxyvitamin D (25-OH vit. D) biomarkers exposed workers.
Summary A total of 3961 married couples from six major geographical areas representing the South Sinai governorates in Egypt were studied to assess rate consanguineous marriage. The population selected (St Catherines, Nuweiba, Abu Rudeis, Ras Sudr, El Tor and Zenima) subdivided into Bedouin, urban mixed populations. questionnaire-based interview was conducted showing that consanguinity this region is 37.5%, with highest recorded Rudeis (52.3%) lowest Nuweiba (24.1%). Consanguinity...
AIM: The study aimed to investigate effects of organic dust exposure from different sources on aflatoxin B1-albumin adducts (AFB1/Alb), and role glutathione S-transferase (GST) gene polymorphism in hepatotoxicity (AFB1) among exposed workers. MATERIAL AND METHODS: Liver enzymes, AFB1/Alb, GST were estimated 132 wheat flour 87 woods sawmill workers, 156 controls.RESULTS: Results revealed that AFB1/Alb liver enzymes significantly elevated workers compared controls, higher with GSTT1...