A5040158309- Restless Legs Syndrome Research
- Parkinson's Disease Mechanisms and Treatments
- Sleep and Wakefulness Research
- Sleep and related disorders
- Dysphagia Assessment and Management
- Circadian rhythm and melatonin
- Obstructive Sleep Apnea Research
- Neurological disorders and treatments
- Neuroscience of respiration and sleep
- Migraine and Headache Studies
- Parkinson's Disease and Spinal Disorders
- Stress Responses and Cortisol
- Child Nutrition and Feeding Issues
- Schizophrenia research and treatment
- Personality Disorders and Psychopathology
- Adrenal Hormones and Disorders
- Attention Deficit Hyperactivity Disorder
- Tryptophan and brain disorders
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Delphi Technique in Research
- Epilepsy research and treatment
- Olfactory and Sensory Function Studies
- Stuttering Research and Treatment
- Sleep and Work-Related Fatigue
- Neurotransmitter Receptor Influence on Behavior
Sleep Research Society
2008-2024
European Southern Observatory
2019-2023
Hospital Universitario Fundación Jiménez Díaz
2000-2017
Paracelsus Elena Klinik Kassel
2016
Spanish Society of Family and Community Medicine
2013
Instituto de Investigaciones del Sueño
2007-2011
Universidad Autónoma de Madrid
2001-2007
Pfizer (Spain)
2002
National Institute of Mental Health
1992-1999
National Institutes of Health
1994-1998
Summary This European guideline for the diagnosis and treatment of insomnia was developed by a task force Sleep Research Society, with aim providing clinical recommendations management adult patients insomnia. The is based on systematic review relevant meta‐analyses published till June 2016. target audience this includes all clinicians involved in insomnia, patient population adults chronic disorder. GRADE (Grading Recommendations Assessment, Development Evaluation) system used to grade...
<b><i>Objective:</i></b> To assess the effects of gabapentin on sensory and motor symptoms in patients with restless legs syndrome (RLS). <b><i>Methods:</i></b> Patients RLS (22 idiopathic, 2 secondary to iron deficiency) were randomized treated for 6 weeks either or placebo. After a 1-week washout they crossed over alternative treatment weeks. rated at baseline scheduled intervals by Rating Scale, Clinical Global Impression, pain analogue scale, Pittsburgh Sleep Quality Index. At end each...
A Task Force was established by the International Restless Legs Syndrome Study Group (IRLSSG) in conjunction with European (EURLSSG) and RLS Foundation (RLS-F) to develop evidence-based consensus-based recommendations for prevention treatment of long-term pharmacologic dopaminergic-induced augmentation restless legs syndrome/Willis–Ekbom disease (RLS/WED). The made following recommendations: As a means prevent augmentation, medications such as α2δ ligands may be considered initial RLS/WED...
Brain iron deficiency has been implicated in the pathophysiology of RLS, and current RLS treatment guidelines recommend when peripheral levels are low. In order to assess evidence on oral intravenous (IV) periodic limb movement disorder (PLMD) adults children, International Restless Legs Syndrome Study Group (IRLSSG) formed a task force review these studies provide evidence-based consensus for adults, PLMD children.A literature search was performed identify papers appearing MEDLINE from its...
A Task Force was established by the International Restless Legs Syndrome Study Group (IRLSSG) to develop evidence-based and consensus-based recommendations for long-term pharmacologic treatment of restless legs syndrome/Willis–Ekbom disease (RLS/WED). The reviewed results all studies RLS/WED treatments with durations 6 months or longer presented at meetings over past 2 years, posted on Web sites pharmaceutical companies, published in peer-reviewed journals, asking questions, "What is...
Rationale: Excessive daytime sleepiness is a common disabling symptom in obstructive sleep apnea syndrome.Objectives: To evaluate the efficacy and safety of pitolisant, selective histamine H3 receptor antagonist with wake-promoting effects, for treatment patients moderate to severe refusing continuous positive airway pressure treatment.Methods: In an international, multicenter, double-blind, randomized (3:1), placebo-controlled, parallel-design trial, pitolisant was individually titrated at...
Dopaminergic medications relieve symptoms of the restless legs syndrome (RLS) but have potential to cause iatrogenic worsening (augmentation) RLS with long-term treatment. Pregabalin may be an effective alternative.In this 52-week, randomized, double-blind trial, we assessed efficacy and augmentation in patients who were treated pregabalin as compared placebo pramipexole. Patients randomly assigned receive 52 weeks treatment at a dose 300 mg per day or pramipexole 0.25 0.5 12 followed by 40...
Context.—Chronic fatigue syndrome (CFS) is associated with a dysregulated hypothalamic–pituitary adrenal axis and hypocortisolemia.Objective.—To evaluate the efficacy safety of low-dose oral hydrocortisone as treatment for CFS.Design.—A randomized, placebo-controlled, double-blind therapeutic trial, conducted between 1992 1996.Setting.—A single-center study in tertiary care research institution.Patients.—A total 56 women 14 men aged 18 to 55 years who met 1988 Centers Disease Control...
Since the publication of first European Federation Neurological Societies (EFNS) guidelines in 2005 on management restless legs syndrome (RLS; also known as Willis-Ekbom disease), there have been major therapeutic advances field. Furthermore, RLS is now a part routine neurological practice Europe. New drugs become available, and further randomized controlled trials undertaken. These were undertaken by EFNS collaboration with Society Sleep Research Society.To provide an evidence-based update...
Restless legs syndrome (RLS) is a neurological disorder with lifetime prevalence of 3-10%. in European studies. However, the diagnosis RLS primary care remains low and mistreatment common. The current article reports on considerations management that were made during Legs Syndrome Study Group (EURLSSG)-sponsored task force consisting experts practioners. sought to develop better understanding barriers practice overcome these diagnostic treatment algorithms. identified by include presentation...