A5091396312- Restless Legs Syndrome Research
- Parkinson's Disease Mechanisms and Treatments
- Sleep and Wakefulness Research
- Epilepsy research and treatment
- Sleep and related disorders
- Pharmacological Effects and Toxicity Studies
- Obstructive Sleep Apnea Research
- Neuroscience and Neuropharmacology Research
- Transcranial Magnetic Stimulation Studies
- Peripheral Neuropathies and Disorders
- Dysphagia Assessment and Management
- Neuroscience of respiration and sleep
- Autoimmune Neurological Disorders and Treatments
- EEG and Brain-Computer Interfaces
- Hemoglobinopathies and Related Disorders
- Neurological disorders and treatments
- Migraine and Headache Studies
- Vestibular and auditory disorders
- Genetics and Neurodevelopmental Disorders
- Autoimmune and Inflammatory Disorders Research
- Cardiovascular Syncope and Autonomic Disorders
- Sleep and Work-Related Fatigue
- COVID-19 and Mental Health
- Infectious Diseases and Tuberculosis
- Metabolism and Genetic Disorders
Keimyung University
2016-2025
Keimyung University Dongsan Medical Center
2014-2024
Medtronic (United States)
2024
Korea University
2024
Deleted Institution
2023
Pusan National University Yangsan Hospital
2023
Soongsil University
2019-2022
University of California, Irvine
2021-2022
Inje University
2022
In-Q-Tel
2021
To evaluate the efficacy and safety of perampanel 2, 4, 8 mg/day added to 1-3 concomitant antiepileptic drugs (AEDs) in patients with uncontrolled partial-onset seizures.During this double-blind, placebo-controlled trial, persisting seizures on AEDs were randomized or placebo following a 6-week baseline phase. Perampanel was titrated weekly by 2 maintained at dose achieved for 13 weeks. Primary endpoints median percent change seizure frequency 50% responder rate. Analysis covariance...
The purposes of this study were to standardize and validate a Korean version the Insomnia Severity Index (ISI-K), evaluate its clinical usefulness.We translated ISI into then it back English check accuracy. 614 patients with sleep disorders who enrolled in comprised 169 primary insomnia, 133 comorbid 312 obstructive apnea. All subjects underwent one night polysomnography (PSG) completed versions both Pittsburgh Sleep Quality (PSQI-K) Epworth Sleepiness Scale, as well ISI-K. ISI-K was...
Brain iron deficiency has been implicated in the pathophysiology of RLS, and current RLS treatment guidelines recommend when peripheral levels are low. In order to assess evidence on oral intravenous (IV) periodic limb movement disorder (PLMD) adults children, International Restless Legs Syndrome Study Group (IRLSSG) formed a task force review these studies provide evidence-based consensus for adults, PLMD children.A literature search was performed identify papers appearing MEDLINE from its...
There is no scale for rating the severity of autoimmune encephalitis (AE). In this study, we aimed to develop a novel in patients with diverse AE syndromes and verify reliability validity developed scale.The key items were generated by panel experts selected according content ratios. The was initially applied 50 (development cohort) evaluate its acceptability, reproducibility, internal consistency, construct validity. Then, another independent cohort (validation cohort, n = 38).A new...
Background and Purpose— Acute ischemic stroke in the distribution of anterior inferior cerebellar artery (AICA) is known to be associated with vertigo, nystagmus, facial weakness, gait ataxia. Few reports have carefully examined deafness AICA infarction. Furthermore, previous neurological not emphasized inner ear as a localization sudden deafness. The aim this study was investigate incidence infarction sites predominantly involved Methods— Over 2 years, we prospectively identified 12...
The shortage of cadaveric donor kidneys for transplantation has forced a re-evaluation the limits on age acceptability. However, as more from older donors have been transplanted, significantly lower graft survival noted among their recipients. impact utilizing and relative importance with respect to other factors not clarified. A total 43,172 cadaver transplants reported UNOS Scientific Renal Transplant Registry between 1987 1995 were subjects this study. Cox regression analysis was utilized...
Insomnia is a common complaint in adults. However, large epidemiologic studies of insomnia involving Asian populations are rarely reported. We performed an study Korean adult population.A total 5,000 subjects (2,470 men and 2,530 women) were interviewed by telephone. A representative sample aged 20 to 69 years was constituted according stratified, multistage random sampling method. defined as either any difficulty getting sleep or back after waking the night.More than one fifth (n=1,141,...
To investigate the prevalence of restless legs syndrome (RLS) in Korea. A large population-based telephone interview method using Korean version Johns Hopkins diagnostic for RLS. computer aided total 5,000 subjects (2,470 men and 2,530 women) were interviewed depth. representative sample aged 20 to 69 years was constituted according a stratified, multistage random sampling method. N/A Of respondents, 373 respondents (7.5%) population (pop) met criteria definite or probable RLS groups: 194...
Obstructive sleep apnea (OSA) and chronic insomnia are two common disorders both considered independent risk factors for heart disease. The aim of this study was to investigate the prevalence comorbid with OSA compare its clinical characteristics those without insomnia. Patients who visited tertiary university hospital centers were screened. Those a diagnosis using polysomnography divided into groups based on their scores Korean version Insomnia Severity Index (ISI-K): (OSA+I) (ISI-K score ≥...
BACKGROUND.: In kidney transplant, obesity was reported to be associated with increased posttransplant complications and worse survival outcomes. The impact of in simultaneous pancreas-kidney (SPK) transplant is less known. METHODS.: Using Organ Procurement Transplantation Network/United Network for Sharing data as August 2008, we included all adults (>18 years) type 1 diabetic SPK recipients between years 2000 2007 a pretransplant body mass index (BMI) 18.5 40 kg/m. cohort divided three...
The aim of this study was to compare the sleep quality between rheumatoid arthritis (RA) patients and healthy controls; evaluate relationship RA disease activity in Korea.A total 130 67 age- sex-matched controls were enrolled a comparative using Pittsburgh Sleep Quality Index (PSQI). Age, gender, concomitant medication, erythrocyte sedimentation rate, serum C-reactive protein, Beck Depression Inventory second edition (BDI-II), 28 joints score (DAS28), pain visual analog scale (VAS), PSQI...
Abstract Background Two clinical scoring systems, the status epilepticus severity score (STESS) and epidemiology-based mortality in (EMSE), are used to predict patients with (SE). The aim of this study was compare outcome-prediction function two systems regarding in-hospital using a multicenter large cohort adult SE. Moreover, we studied potential role these predicting functional outcome Methods SE consisted from epilepsy centers eight academic tertiary medical South Korea....
Nasal polyps and inverted papillomas often look similar. Clinically, it is difficult to distinguish the masses by endoscopic examination. Therefore, in this study, we aimed develop a deep learning algorithm for computer-aided diagnosis of nasal images, which may provide more accurate clinical before pathologic confirmation masses.
Background Cryptogenic new-onset refractory status epilepticus (cNORSE) currently lacks comprehensive knowledge regarding its clinical dynamics, prognostic factors and treatment guidance. Here we present the longitudinal profiles, predictive for outcomes optimal duration of immunotherapy in patients with cNORSE. Methods This retrospective secondary endpoint analysis investigated cNORSE identified from a prospective autoimmune encephalitis cohort at national referral centre Korea. The main...
Background: A Korean family had distinctive clinical and neuroimaging features carried the same genetic mutation that was found in a previously described Japanese kindred with autosomal dominant nocturnal frontal lobe epilepsy.Objective: To describe first epilepsy.Methods: Members of large family, including 9 affected individuals from 3 generations, underwent comprehensive genetic, clinical, electroencephalographic, neuropsychological, evaluation.Affected members were tested for possible...
Sleep disturbance is prime concern in patients with Behcet disease. The purpose of this study was to find out the effects sleep quality, Korean suffering from We further investigated relationship between depression, quality life and clinical findings