Seçil Tan

ORCID: 0000-0003-1104-7253
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About
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Research Areas
  • Reproductive Biology and Fertility
  • Pluripotent Stem Cells Research
  • Ocular Diseases and Behçet’s Syndrome
  • Animal Genetics and Reproduction
  • Cancer-related molecular mechanisms research
  • RNA modifications and cancer
  • Otitis Media and Relapsing Polychondritis
  • Sirtuins and Resveratrol in Medicine
  • Injury Epidemiology and Prevention
  • Electromagnetic Fields and Biological Effects
  • MicroRNA in disease regulation
  • Autophagy in Disease and Therapy
  • RNA Research and Splicing
  • Inflammasome and immune disorders
  • Reproductive System and Pregnancy
  • Agriculture and Farm Safety
  • Pregnancy-related medical research
  • Systemic Lupus Erythematosus Research
  • Pregnancy and preeclampsia studies

Pamukkale University
2021-2025

Guangxi University
2001

Abstract Epithelial ovarian cancer (EOC) is the second leading cause of death among women with gynecological cancers, particularly in high-income countries. Despite significant advancements molecular oncology and an initially positive response to primary chemotherapy, development drug resistance remains a major challenge effective management EOC. Consequently, there urgent need for innovative biological markers that can enable early diagnosis provide more accurate predictions recurrence risk...

10.1007/s12032-025-02628-1 article EN cc-by Medical Oncology 2025-02-24

Contemporary nuclear transfer techniques often require the involvement of skilled personnel and extended periods micromanipulation. Here, we present details development a technique for somatic cells that is both simpler faster than traditional methods. The comprises bisection zona-free oocytes reconstruction embryos comprising two half cytoplasts cell by adherence using phytohaemagglutinin-P (PHA) followed an electropulse subsequent culture in microwells (termed WOWs - well well). system was...

10.1089/153623001753205098 article EN Cloning and Stem Cells 2001-09-01

The recent demonstration of a successful zona-free manipulation technique for bovine somatic nuclear transfer (NT) that is both simpler and less labor intensive considerable benefit to advance the applications this technology. Here, we describe method also applicable porcine NT. Porcine cumulus oocyte complexes were matured in TCM-199 medium before sequential removal zonae. Zona-free oocytes bisected using microknife, halves containing metaphase plate (as determined by Hoechst 33342...

10.1089/15362300152725909 article EN Cloning and Stem Cells 2001-12-01

MicroRNAs (miRNAs) are involved in a range of pathological and biological processes. Vascular involvement is an important complication associated with morbidity mortality Behçet's disease (BD). In this study, we aimed to evaluate the expression levels miR-195, miR-424, miR-10b, miR-103a-3p, miR-542-3p Turkish patients BD, their possible association vascular clinical activity.

10.31138/mjr.030623.elc article EN Mediterranean Journal of Rheumatology 2024-06-01

Bryonia multiflora, one of the species L. (Cucurbitaceae) genus, is a perennial, dioecious, herbaceous plant with rhizome-shaped roots. have anti-inflammatory, antimicrobial, cytotoxic, antioxidant, etc., activities and their components consume antitumoral effects. Purpose study to investigate effect Multiflora extract (BMST) on breast cancer cells. Our results revealed that MCF-7 MDA-MB-231 cells underwent significant morphological changes leading cell rounding. No were observed in...

10.1080/01635581.2021.1922717 article EN Nutrition and Cancer 2021-05-22
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