Krupa Subramanian

ORCID: 0000-0003-1105-0436
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About
Contact & Profiles
Research Areas
  • HIV Research and Treatment
  • BRCA gene mutations in cancer
  • Immune Cell Function and Interaction
  • HIV/AIDS Research and Interventions
  • Cell Image Analysis Techniques
  • Agricultural risk and resilience
  • Income, Poverty, and Inequality
  • Advanced Biosensing Techniques and Applications
  • HIV/AIDS drug development and treatment
  • Genetic factors in colorectal cancer
  • Agricultural Economics and Practices
  • Anomaly Detection Techniques and Applications
  • Cytomegalovirus and herpesvirus research
  • Health Systems, Economic Evaluations, Quality of Life
  • T-cell and B-cell Immunology

Southern Research Institute
2017-2022

American College, Madurai
2020

Emory University
2019

University of Pennsylvania
2003

Temple University
2003

Abstract Life insurance industry access to genetic information is controversial. Consumer groups argue that will increase discrimination in life premiums and discourage individuals from undergoing testing may provide health benefits. Conversely, insurers without risk available individuals, they face substantial financial adverse selection. Given this controversy, we conducted a retrospective cohort study evaluate the impact of breast cancer on purchasing, concerns about use BRCA1 / 2...

10.1002/ajmg.a.20025 article EN American Journal of Medical Genetics Part A 2003-04-11

ABSTRACT Genetic testing is a concern for insurers if they cannot use test results in underwriting. We model adverse selection an insurance market with genetic breast and ovarian cancer. Increased forces of mortality resulting from family history cancer or positive BRCA mutation are calculated. Using Markov model, we estimate costs selection, assuming various purchase behaviors. Adverse should be controllable companies apply strict underwriting rules, requesting onset age all first-degree...

10.2307/253862 article EN Journal of Risk & Insurance 1999-12-01

Studies have demonstrated that intensive ART alone is not capable of eradicating HIV-1, as the virus rebounds within a few weeks upon treatment interruption. Viral rebound may be induced from several cellular subsets; however, majority proviral DNA has been found in antigen experienced resting CD4+ T cells. To achieve cure for eradication strategies depend both understanding mechanisms drive HIV-1 persistence well sensitive assays to measure frequency infected cells after therapeutic...

10.1371/journal.ppat.1008074 article EN public-domain PLoS Pathogens 2019-10-14

Achieving a functional or sterilizing cure for HIV will require identification of therapeutic interventions that reduce reservoir size in infected individuals. Proteasome inhibitors, such as ixazomib, impact multiple aspects biology including latency, transcription initiation, viral replication, and cell killing through the protease - Casp8p41 pathway, resulting latency reversal reduced measures ex vivo.

10.1016/j.eclinm.2021.101225 article EN cc-by EClinicalMedicine 2021-11-29

T. R. Malthus propounded a theory of the relationship between population growth and economic development. He wrote an essay in 1798 on "The Principles Population'. said that increases geometric ratio (i.e., 10, 20, 40, 80…) whereas, food supply only arithmetic 30, 40…).He stated 'nature will restore equilibrium, if man fails to check his own growth'.

10.24247/ijecrjun202015 article EN International Journal of Economics Commerce and Research 2020-01-01
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