About
Contact & Profiles
A5023647319
Research Areas
- Oral and Maxillofacial Pathology
- Sarcoma Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
Capital Medical University
2019
Purpose: Chordomas are locally aggressive tumors arising from notochordal remnants. Brachyury, a protein coded by T-gene, is crucial for chordoma cell proliferation. The aim of this study was to evaluate the effects glycogen synthase kinase 3 beta (GSK3β) activity on brachyury expression and growth survival skull base cells. Patients methods: In study, 16 paraffin-embedded specimens primary chordomas were analyzed phosphorylated GSK3β using immunohistochemistry. UM-Chor1 line derived clival...
10.2147/ott.s218930
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OncoTargets and Therapy
2019-11-01
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