Abstract Ferroptosis therapy, which uses ferroptosis inducers to produce lethal lipid peroxides and induce tumor cell death, is considered a promising cancer treatment strategy. However, challenges remain regarding how increase the accumulation of reactive oxygen species (ROS) in microenvironment (TME) enhance antitumor efficacy. In this study, hyaluronic acid (HA) encapsulated hollow mesoporous manganese dioxide (H‐MnO 2 ) with double‐shell nanostructure designed contain iron coordinated...

Abstract Polyphenol hydrogels have found widespread application in wound healing, bone repair, drug delivery, and biosensors due to their robust wet adhesion, high ductility, excellent self‐healing ability. However, these often exhibit low intrinsic cohesion, which limits overall adhesive strength. Enhancing cohesion is critical for improving both the adhesion mechanical properties of hydrogels, thereby expanding utility biomedical fields. This review begins by exploring strategies enhance...

Soft wall-climbing robots have been limited in their ability to perform complex locomotion diverse environments due structure and weight. Thus far, soft with integrated functions that can locomote 3-D are yet be developed. This article addresses this challenge by presenting a lightweight (2.57 g) robot linear, turning, transitioning motion capabilities. The employs three pneumatic bending actuators two adaptive electroadhesion pads, which enable it flip forward, transition between walls,...

Al aser interferometer combined with a reference mirror suspended on long-period folded pendulum is presented to measure the low-frequency horizontal seismic spectrum. One of reflecting mirrors driven by piezoelectric transducer track another mirror. The experimental results show that motion about 10 −9 mH z −1/2 at 1 Hz in

We created a finite-element model of the head-disk assembly (HDA) small-form factor drive. conducted operational shock simulation and modal analysis with this model, investigated pulsewidth effect half-sine acceleration pulse on responses. found that umbrella mode disk is dominant for shock. Numerical results maximum responses further confirm conclusions in previous work by authors.

The quantized surface mode technique was used to calculate the zero-point energy between two anisotropic parallel plates with nontrivial magnetic properties, one of which is dielectric and other permeable. analytical approximate expressions Casimir force torque were obtained in retarded limit. repulsive effect can be acquired for some materials suitable permittivities permeabilities, might measured a future experiment.

Electromechanical instability has limited the capacity of a dielectric elastomer (DE) either as an actuator or sensor. The effects entanglements on electromechanical stability DEs were generally not considered previously. In this letter, based recently developed true method, we employ physics-based nonaffine model to analyze chain pull-in ideal DE subject biaxial prestresses. It is indicated that more entangled exhibits higher critical nominal electric field and smaller actuation stretch....

It is widely recognized that the extension limit of polymer chains has a significant effect on snap-through instability dielectric elastomers (DEs). The performance DEs been extensively studied by two limited-stretch models, i.e., eight-chain model and Gent model. However, real networks usually have many entanglements due to impenetrability network as well finite extensibility resulting from full stretching chains. effects cannot be captured previous models. In this paper, nonaffine proposed...

Abstract Large-scale high sensitivity laser gyroscopes have important applications for ground-based and space-based gravitational wave detection. We report on the development of a 3 m × heterolithic passive resonant gyroscope (HUST-1) which is installed ground cave laboratory. operate HUST-1 different longitudinal cavity modes rotation reaches 1.6 10 −9 rad s −1 Hz −1/2 above 1 Hz. The drift length one major limits our in low frequency regime. By locking to an ultra-stable reference laser,...

Relaxor ferroelectric single crystals exhibit anisotropic piezoelectric behavior. This enables the use of a combination crystal cut and poling to obtain properties optimized for certain applications. work describes that is applications where strong face shear mode d312 coupling desired with zero d311 or d322 coefficient. Such production stack actuators in long bar shape electric field perpendicular length. These bars can be cantilevered mass at end produce highly sensitive accelerometer. The...

Radiotherapy is the main treatment modality for various pelvic malignancies. However, high intensity radiation can damage functional bone marrow (FBM), resulting in hematological toxicity (HT). Accurate identification and protection of FBM during radiotherapy planning reduce HT. The traditional manual method contouring time-consuming laborious. Therefore, development an efficient accurate automatic segmentation mode provide a distinct leverage clinical settings. In this paper, we propose...

An optical modulator of a metasurface constructed by an arrayed nano-ridge-aperture with central nano-cylinder (NRANC) is designed and fabricated. The coupling effect between the localized surface plasmons (LSPs) distributed over each nano-apex outer-edge nano-cylinder, polaritons (SPPs) generated periodic metasurface, have been investigated carefully. tapered structure can be utilized to concentrate incident energy also remarkably enhance light-field. electrical dipolar induced on will...

We investigated the Raman-pulse-duration effect in a gravity gradiometer with two atom interferometers. Since clouds experience different gravitational fields, it is hard to compensate for Doppler shifts of simultaneously by chirping frequency common Raman laser. This leads an appreciable phase shift. The magnitude shift relative differential interferometers order $\ensuremath{\tau}/T$, and cannot be neglected precision measurements such as measuring gradient Newtonian constant.

Relaxor-PT single crystals are at the forefront of advanced transducer applications, including medical ultrasound and high power sonar. In this work, we report on recent developments in crystals, specifically increased temperature usage crystallographic domain engineering relationships. Furthermore, contrast with respect to both ldquosoftrdquo ldquohardrdquo piezoelectric ceramics, namely Pb(Zr,Ti)O <sub xmlns:mml="http://www.w3.org/1998/Math/MathML"...

Piezoelectric materials lie at the heart of electromechanical transducers. Applications include actuators, ultrasonic imaging and high intensity focused ultrasound (HIFU), underwater sonar, non-destructive evaluation (NDE), resonators, pressure sensors accelerometers to name a few. In this work, we report on recent developments shear properties Relaxor-PT single crystals with different phases orientations, as function temperature applied fields. Specifically, piezoelectric d <sub...

Due to the unclear seepage mechanism for shale oil, it is hard establish a reasonable mathematical model describe flowing law. In this study, real pore structure was reconstructed with CT scanning and numerical of fluid in developed COMSOL, based on boundary slip at micro-nano scale study causes nonlinear seepage. A two-fluid employed simple relationship between flow rate pressure gradient using effective length account influence true slip, established verified experimental data coming from...

In the processing of temperature and atmospheric pressure data observed in an underground laboratory, cross-correlation equilibrium method is proposed for determining phase a signal with particular frequency. This effectively suppresses influence white noise reduces errors derived from higher order harmonics any direct current component experimental signal. The upper limit error due to other frequencies estimated. Theoretical analysis result computational simulation show that signal-to-noise...

Ongoing developments in computational databases seek to improve the accessibility and breadth of high-throughput screening materials discovery efforts. Their reliance on experimental crystal structures necessitates significant processing prior computation order resolve any crystallographic disorder or partial occupancies remove residual solvent molecules case activated porous materials. Contemporary investigations revealed that deficiencies characterization preprocessing methods generated...

A symmetric disc-shaped torsion pendulum was designed to study the nonlinear effects of fiber. It showed that period decreases with amplitude oscillation. Determination unperturbed through a fit measured data variation shows this systematic error in measurement Newtonian gravitational constant G by time-of-swing method can be reduced an order magnitude at least.

Performances of an accelerometer suspended by a pendulum and set on ground directly are both discussed. Theoretical analysis shows that the isolation from seismic disturbances such suspending is equal to narrow band-pass electronic filter. This means effect noises can be substantially suppressed suspension during its performance tests.

Electrostatic layer jamming (ELJ) is a method toachieve variable stiffness in soft robotics. Traditional ELJ focuses on Direct Current(DC) voltages and ignores Alternating Current(AC) voltages. In this paper, by applying AC of different frequencies to three devices (ELJ-AIR, ELJGERF, ELJ-OIL) based dielectric materials(air, giant electrorheological fluid, silicone oil), we discuss the effect voltage its frequency performance devices. The experimental results show that application can...

The Maoming basin in south China is rich oil shale resources, whereas the Youganwo formation a potential area for large-scale situ exploration because of its relatively large thickness, high content, and good continuity. Based on previous geologic studies laboratory experimental data, pyrolysis models are established using CMG-STARS software to simulate heating reactions. To analyze major influencing factors, CMOST module employed conduct sensitivity analysis with accumulated gas production...

We generalize Kupisewska method to the three-dimensional system and another derivation of Casimir effect between two dielectric plates is presented based on explicit quantization electromagnetic field in presence dielectrics, where physical meaning ``evanescent mode'' discussed. The Lifshitz's formula rederived using all vacuum mode functions, which include contribution `evanescent modes'. Only case perfect metallic will evanescent modes become unimportant.