- Glycosylation and Glycoproteins Research
- Carbohydrate Chemistry and Synthesis
- Extracellular vesicles in disease
- Adsorption and biosorption for pollutant removal
- MicroRNA in disease regulation
- Web and Library Services
- Circular RNAs in diseases
- Inorganic and Organometallic Chemistry
- Nanomaterials for catalytic reactions
- Chemical Synthesis and Characterization
- Medical Imaging Techniques and Applications
- Studies on Chitinases and Chitosanases
- Mobile Learning in Education
- Supercapacitor Materials and Fabrication
- Lanthanide and Transition Metal Complexes
- Galectins and Cancer Biology
- Web Data Mining and Analysis
- Advanced MRI Techniques and Applications
- Genomics and Phylogenetic Studies
- Nanoplatforms for cancer theranostics
National Taiwan University
2022-2024
Institute of Atomic and Molecular Sciences, Academia Sinica
2022-2024
Academia Sinica
2022-2024
Batangas State University
2017-2019
The University of Queensland
2017
Extracellular vesicles (EVs) are released by cells to mediate intercellular communication under pathological and physiological conditions. While small EVs (sEVs; <100-200 nm, exosomes) intensely investigated, the properties functions of medium large (big (bEVs); >200 microvesicles) less well explored. Here, bEVs sEVs identified as distinct EV populations, it is determined that in a greater bEV:sEV ratio aggressive human triple-negative breast cancer (TNBC) subtype. PalmGRET,...
19F magnetic resonance imaging (MRI) is a powerful noninvasive technique with demonstrated potential for the detection of important diseases. The major challenge in design MRI agents signal attenuation caused by reduced solubility and segmental mobility probes high numbers fluorine atoms. Careful choice fluorinated moiety required to maintain image quality at contents sensitivity. Here we report synthesis perfluoropolyether (PFPE) end-functionalized homopolymers oligo(ethylene glycol) methyl...
N-linked glycosylation is one of the most important post-translational modifications proteins. Current knowledge multicellular eukaryote N-glycan biosynthesis suggests high mannose N-glycans are generated in endoplasmic reticulum and Golgi apparatus through conserved biosynthetic pathways. According to conventional pathways, four Man7GlcNAc2 isomers, three Man6GlcNAc2 Man5GlcNAc2 isomer during this process. In study, we applied our latest mass spectrometry method, logically derived sequence...
-Linked glycosylation is one of the most essential post-translational modifications proteins. However,
The use of activated carbon (AC) from lignocellulosic wastes has gained a lot research interest because its great economic and environmental value. In this work, AC was prepared mahogany fruit husk (MFH) via chemical activation with phosphoric acid heat treatment. relationships among the parameters H3PO4%, heating temperature, holding time, their effect on chromium (VI) removal, were investigated using response surface method (RSM), following central composite design (CCD). optimized...
The present study is focused on the use of activated carbon derived from water hyacinth (WH-AC) as adsorbent for removal Cr(VI) aqueous solution. optimized WH-AC was found to be mesoporous and considered granular. surface area 11.564 m2/g have a good adsorption capacity. data followed pseudo-second order kinetics Freundlich isotherm model. Based correlation coefficient obtained pseudo-second-order kinetic model, R2 values were all above 0.99, which closer unity one (1) indicating that it...
N-linked glycosylation is one of the most important post-translational modifications proteins. Current knowledge multicellular eukaryote N-glycan biosynthesis suggests high mannose N-glycans are generated in endoplasmic reticulum and Golgi apparatus through conserved biosynthetic pathways. As a part modifications, lipid dolichol-phosphate linked oligosaccharide Glc3Man9GlcNAc2 transferred to proteins, glucoses sequentially removed by various ER- Golgi-localized glucosidases...
Extracellular vesicles (EVs) are released by cells to mediate intercellular communication under pathological and physiological conditions. While small EVs (sEVs; <100–200 nm, exosomes) intensely investigated, the properties functions of medium large (big [bEVs]; >200 microvesicles) less well explored. Here, we identify bEVs sEVs as distinct EV populations, determine that in a greater bEV:sEV ratio aggressive human triple-negative breast cancer (TNBC) subtype. PalmGRET, bioluminescence...