Maria João Sousa

ORCID: 0000-0003-1125-2871
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About
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Research Areas
  • Head and Neck Cancer Studies
  • Colorectal Cancer Treatments and Studies
  • Cancer Treatment and Pharmacology
  • Urinary and Genital Oncology Studies
  • Advanced Breast Cancer Therapies
  • Bladder and Urothelial Cancer Treatments
  • Cancer Diagnosis and Treatment
  • Cancer survivorship and care
  • COVID-19 and healthcare impacts
  • Urological Disorders and Treatments
  • Cancer Genomics and Diagnostics
  • Lung Cancer Treatments and Mutations
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Gastric Cancer Management and Outcomes
  • Breast Cancer Treatment Studies
  • Brain Metastases and Treatment
  • Neuroendocrine Tumor Research Advances
  • Breast Lesions and Carcinomas
  • Vaccine Coverage and Hesitancy
  • Economic and Financial Impacts of Cancer
  • Consumer Attitudes and Food Labeling
  • Nutritional Studies and Diet
  • Gestational Trophoblastic Disease Studies
  • Sensory Analysis and Statistical Methods
  • Cancer and Skin Lesions

Hospital de Santo António
2025

Administração Regional de Saúde de Lisboa e Vale do Tejo
2024

Instituto Português de Oncologia de Coimbra Francisco Gentil
2020-2023

Centro Hospitalar do Porto
2023

Universidade Lusófona
2023

Centro Hospitalar de Vila Nova de Gaia
2023

Hospital de São João
2023

Hospitais da Universidade de Coimbra
2023

European Institute of Oncology
2022

Istituti di Ricovero e Cura a Carattere Scientifico
2022

The wine industry generates large amounts of by-products that are usually destined as waste. Grape pomace is the residue winemaking process and rich in compounds with functional properties, such dietary fiber phenolic compounds. aim this research was to study influence white red grape flour (GPF) addition enhancement properties savory crackers. Different levels incorporation were tested (5%, 10% 15% (w/w)). Analysis physical nutritional composition sensory acceptability conducted evaluate...

10.3390/foods12071392 article EN cc-by Foods 2023-03-24

Abstract Purpose Transarterial chemoembolisation (TACE) using irinotecan-eluting beads is an additional treatment option for colorectal cancer liver metastases (CRLM) patients that are not eligible curative approaches. This interim analysis focuses on feasibility of the planned statistical regarding data distribution and completeness, intention, safety health-related quality life (HRQOL) first 50 prospectively enrolled in CIrse REgistry LifePearl™ microspheres (CIREL), observational...

10.1007/s00270-020-02646-8 article EN cc-by CardioVascular and Interventional Radiology 2020-09-24

In patients with recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC) the estimated prognosis is usually poor. Patient-specific factors that affect should be considered when choosing therapy. We conducted a retrospective, single-center analysis in treated first line platinum antiEGFR antibody-containing regimen. The objective was to generate real-world data considering treatment outcomes identify predictors of survival.Clinical charts cetuximab platinum-based...

10.1016/j.ctarc.2021.100375 article EN cc-by-nc-nd Cancer Treatment and Research Communications 2021-01-01

The reference to vitiligo-like lesions (VLLs) induced by immune checkpoint inhibitors (ICIs) as a valuable predictive marker of treatment success immunotherapy with ICIs in melanoma has been mentioned the literature. Its role non-small cell lung cancer (NSCLC)-treated patients remains poorly recognized phenomenon uncertain significance regarding its value. A retrospective, observational, single-center report was performed, descriptive analysis clinicopathological and characteristics stage IV...

10.3390/curroncol31020083 article EN cc-by Current Oncology 2024-02-19

Background: The term phyllodes tumours, which account for less than 1% of breast neoplasms, describes a spectrum heterogenous tumours with different clinical behaviours. Less 30% present as metastatic disease. Complete surgical resection is the standard care so that recurrence rates are reduced. role adjuvant chemotherapy or radiation therapy controversial. Patients disease have median overall survival around 30 months. Case description: authors case 57-year-old woman an exuberant left...

10.12890/2021_002763 article EN cc-by-nc-nd European Journal of Case Reports in Internal Medicine 2021-08-23

O artigo analisa teoricamente as desigualdades entre classes sociais nas cidades e no planejamento urbano brasileiro. Além disso, avalia a atuação do Estado institucionalizações da reforma urbana últimas décadas. Com um enfoque crítico ao urbano, é considerado qualitativamente fontes secundárias na literatura em documentos, tal como o Estatuto Cidade. Ainda que os instrumentos urbanísticos Cidade, mediante longo processo de mobilização sociedade civil, tenham alcançado êxito, pela função...

10.18542/ncn.v27i3.13426 article PT cc-by-nc Novos Cadernos NAEA 2024-12-27

Introduction: Colorectal cancer (CRC) is the second-most deadly worldwide. However, there remains a scarcity of precision treatments available for this type cancer. Amplification or overexpression human epidermal growth factor receptor 2 (HER2+) well-established therapeutic target in gastric and breast HER2 positive approximately 5% CRC cases has been implicated resistance to therapy with anti-epidermal antibodies. The aim study was evaluate status RAS BRAF wild-type metastatic (mCRC) its...

10.7759/cureus.42536 article EN Cureus 2023-07-27

The RECOURSE trial supported trifluridine/tipiracil as a treatment option in metastatic colorectal cancer (mCRC). Subsequent analysis demonstrated that low tumour burden and indolent disease are good prognosis factors improving progression-free survival (PFS) overall (OS). This study aimed to evaluate the impact of group OS, PFS safety patients with mCRC. Single-centre, retrospective, observational mCRC who started between February 2018 July 2019. Patients were divided into characteristics...

10.1016/j.ctarc.2022.100531 article EN cc-by-nc-nd Cancer Treatment and Research Communications 2022-01-01

Abstract BACKGROUND Glioblastoma (GBM) is the most common and aggressive primary malignant brain tumour in adults. The current standard of care for newly diagnosed GBM maximal surgical resection, followed by radiotherapy plus concomitant adjuvant temozolomide (TMZ). This study aimed to evaluate survival outcomes identify predictors among these patients. MATERIAL AND METHODS We performed a single-centre retrospective analysis patients treated with TMZ from 2013 2020. analyses progression-free...

10.1093/neuonc/noab180.192 article EN Neuro-Oncology 2021-09-01

Epithelioid trophoblastic tumour (ETT) is a very rare variant of gestational disease, which arises in reproductive-age women with prior history. Because its rarity, biological behaviour, imaging characteristics and therapeutic schedule have not yet been fully established. Here we describe case metastatic ETT premenopausal woman. A 40-year-old, gravida 3, para 2, Portuguese woman was referred to the dermatology department for multiple skin nodules on scalp measuring between 1 6 cm. biopsy...

10.12890/2021_002870 article EN cc-by-nc-nd European Journal of Case Reports in Internal Medicine 2021-10-25

Abstract Funding Acknowledgements Type of funding sources: None. Introduction Electrocardiogram (ECG) is the most performed cardiovascular tool in medicine(1). First described by Einthoven at beginning 20th century, it now a useful, cheap and safe exam, accessible to millions people on devices as light smartwatches. Several studies have demonstrated variability ECG interpretation. A recent systematic review low median accuracy 54%, across different training levels (from students experimented...

10.1093/eurjpc/zwad125.235 article EN European Journal of Preventive Cardiology 2023-05-24

Non-muscle invasive bladder cancer (NMIBC) is a frequently diagnosed neoplasm, which typically managed with transurethral resection of tumor (TURBT) eventually followed by intravesical therapies. Bacillus Calmette-Guérin (BCG) used as first-line adjuvant treatment in high- (HR) and intermediate-risk (IR) NMIBC, although, the latter, mitomycin C (MMC) may also be used. Multiple limitations to use BCG encouraged search for therapeutic alternatives. In this context, hyperthermic chemotherapy...

10.7759/cureus.45672 article EN Cureus 2023-09-21

Abstract Background: Febrile neutropenia (FN) is a major toxicity of anthracycline-taxane based chemotherapy, which actually the most active cytotoxic combination for breast cancer treatment. The standard and widely adopted FEC-D regimen reported initially favorable profile, with global Docetaxel FN rate 11.2% 7.4% respectively. has not been commonly considered by guidelines (ASCO, ESMO, EORTC NCCN) high risk (FN ≥20%), G-CSF primary prophylaxis therefore systematically recommended. We aimed...

10.1158/0008-5472.sabcs13-p3-09-05 article EN Cancer Research 2013-12-15

<ns7:p><ns7:bold>Background: </ns7:bold>Cancer patients are at risk of developing some level psychological dysregulation, depending on a series variables related to the tumor, environment, and patient. In this context, it becomes important define difference between psychiatric disorder study its prevalence. The primary endpoint is evaluate prevalence disorders in sample Portuguese with metastatic breast cancer assess relationship these characteristics oncological disease.</ns7:p><ns7:p>...

10.12688/f1000research.79400.1 preprint EN cc-by F1000Research 2022-01-21

Abstract Purpose Significant changes in treatment centers were implemented during COVID-19 pandemics. Understanding how these alterations impacted cancer patients is a subject that needs to be investigated. Methods Patients who accepted fill hand paper questionnaire included this cross-sectional study. The was distributed between March 19 and April 30, 2020 (first emergency state Portugal) at the Portuguese Oncology Institute of Coimbra Francisco Gentil. Results A total 100 participated...

10.21203/rs.3.rs-1827813/v1 preprint EN cc-by Research Square (Research Square) 2022-07-14
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