A5053998137- Tendon Structure and Treatment
- Shoulder Injury and Treatment
- Knee injuries and reconstruction techniques
- Osteoarthritis Treatment and Mechanisms
- Bone and Joint Diseases
- Hip disorders and treatments
- Shoulder and Clavicle Injuries
- Trauma Management and Diagnosis
- Total Knee Arthroplasty Outcomes
- Mesenchymal stem cell research
- Lower Extremity Biomechanics and Pathologies
- Orthopaedic implants and arthroplasty
- Orthopedic Infections and Treatments
- Orthopedic Surgery and Rehabilitation
- Diabetic Foot Ulcer Assessment and Management
- Periodontal Regeneration and Treatments
- Angiogenesis and VEGF in Cancer
- Hip and Femur Fractures
- Bone fractures and treatments
- Tissue Engineering and Regenerative Medicine
- Peripheral Artery Disease Management
- Sports injuries and prevention
- Exercise and Physiological Responses
- Heat shock proteins research
- Bone health and osteoporosis research
Chang Gung University
2016-2025
Kaohsiung Chang Gung Memorial Hospital
2016-2025
Fooyin University
2019-2021
Weatherford College
2021
Kaohsiung Medical University
2019
ShockWave Medical (United States)
2017-2018
University of Pittsburgh
2010-2013
Abstract Soft tissue allografts, such as the bone‐patellar tendon‐bone (BPTB) graft, have been frequently used for anterior cruciate ligament (ACL) reconstruction. As allografts are subjected to freezing and thawing multiple cycles, objective of this study was measure changes biomechanical properties human BPTB allograft after 4 8 freeze–thaw cycles in comparison a single cycle. Three specimens were procured from 21 donors divided into three groups: 1, 4, or cycles. Each cycle consisted at...
We assessed the pathological changes of articular cartilage and subchondral bone on different locations knee after extracorporeal shockwave therapy (ESWT) in early osteoarthritis (OA).Rat knees under OA model by anterior cruciate ligament transaction (ACLT) medial meniscectomy (MM) to induce changes.Among ESWT groups, were applied (M) femur (F) tibia (T) condyles was better than condyle, condyle as well lateral (L) gross osteoarthritic areas (p<0.05),osteophyte formation sclerotic...
Abstract Ligaments and tendons are dense connective tissues that important in transmitting forces facilitate joint articulation the musculoskeletal system. Their injury frequency is high especially for those functional important, like anterior cruciate ligament (ACL) medial collateral (MCL) of knee as well glenohumeral ligaments rotator cuff shoulder. Because healing responses different these after injury, consequences treatments tissue- site-specific. In this review, we will elaborate on...
Extracorporeal shockwave therapy (ESWT) shows chondroprotective effect in osteoarthritis of the rat knees. However, ideal number ESWT is unknown. This study investigated effects different numbers knee rats. Forty-five male Sprague-Dawley rats were divided into five groups. Group I underwent sham arthrotomy without anterior cruciate ligament transection (ACLT) or medial meniscectomy (MM) and received no ESWT. II ACLT + MM III MM, once a week for one treatment. IV twice 2 treatments. V three...
Abstract Introduction This study investigated the effectiveness of extracorporeal shockwave therapy (ESWT) in osteoporotic (OP) osteoarthritis (OA) rat knee. Methods Fifty-six rats were divided into seven groups including sham, OA, OP, OA + ESWT, OP and ESWT groups. The evaluations included gross pathology, bone mineral density (BMD), micro-computed tomography (micro-CT) scan, bone-strength test, histopathologic examination, immunohistochemical analysis. Results On group showed larger areas...
Background: This study tested the hypothesis that hyperbaric oxygen (HBO) therapy enhanced circulating levels of endothelial progenitor cells (EPCs), soluble angiogenesis factors, and blood flow in ischemic areas patients with peripheral arterial occlusive disease (PAOD). Methods: In total, 57 consecutive PAOD undergoing HBO (3 atmospheres (atm) for 2 h each time) were prospectively enrolled into present study. Venous sampling was performed to assess EPCs factors prior during five sessions...
Our study compared the effects of extracorporeal shockwave therapy (ESWT) on subchondral bone and articular cartilage in treatment early osteoarthritis (OA) rat knee. The rats were divided into 5 groups which included Sham group, Meniscus group (ESWT applied medial meniscus), OA (arthrotomy menisectomy (MMx) anterior cruciate ligament transection (ACLT), T(M) MMx ACLT followed by ESWT tibial bone) Articular cartilage). Evaluations pathological changes synovium, bone, with meniscus,...
Extracorporeal shockwave therapy (ESWT) and mesenchymal stem cells (MSCs) have been reported to chondroprotective effects in knee osteoarthritis (OA). Here, we examined whether autologous adipose-derived (ADMSCs) human umbilical cord Wharton’s jelly-derived (WJMSCs) increased the efficacy of ESWT OA, compared two. The treatment groups exhibited significant improvement OA according pathological analysis, micro-computed tomography (CT), immunohistochemistry (IHC) staining. ADMSCs ESWT+ADMSCs...
Extracorporeal shock wave (ECSW) and adipose-derived mesenchymal stem cells (ADMSCs) have been recognized to capacities of anti-inflammation angiogenesis. We tested the hypothesis that ECSW ADMSC therapy could attenuate ischemia-reperfusion- (IR-) induced thigh injury (femoral artery tightened for 6 h then tightness was relieved) in rats. Adult male SD rats (n = 30) were divided into group 1 (sham-control), 2 (IR), 3 (IR + ECSW/120 impulses at 0.12 mJ/mm2 given h/24 h/72 after IR), 4...
The dose-dependent effects of adipose-derived mesenchymal stem cell-conditioned medium (ADSC-CM) were compared with those shockwave (SW) therapy in the treatment early osteoarthritis (OA). Anterior cruciate ligament transaction (ACLT) medial meniscectomy (MMx) was performed rats divided into sham, OA, SW, CM1 (intra-articular injection 100 μL ADSC-CM knee OA), and CM2 200 ADSC-CM) groups. Cartilage grading, grading synovium changes, specific molecular analysis by immunohistochemistry...
VP1 of the chicken anemia virus (CAV) is a structural protein that required for encapsulation. proteins are present both in nucleus and cytoplasm; however, functional nuclear localization signal (NLS) export (NES) still unknown. This study aimed to characterize NLS NES motifs using bioinformatics methods multiple-site fragment deletions, investigate shuttling VP2 from cytoplasm by co-transfection with VP1.Two putative were predicted WoLF PSORT NLStradamus programs amino acid sequence VP1....
Abstract Background Acromioclavicular joint (ACJ) dislocation is a relatively common shoulder injury. For the treatment of cases severe ACJ (Rockwood type III–V), hook plate fixation an easy-to-master and minimally-invasive approach to surgical intervention. Over stress on acromion following often leads acromial complications such as osteolysis loss reduction. We hypothesized that suspensory reconstruction alongside might provide superior stability reduce compared with alone. The purpose...
To explore the efficacy of extracorporeal shockwave therapy (ESWT) in treatment osteochondral defect (OCD), and its effects on levels transforming growth factor (TGF)-β, bone morphogenetic protein (BMP)-2, -3, -4, -5, -7 terms cartilage regeneration.