Yi Zhang

ORCID: 0000-0003-1150-6042
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About
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Research Areas
  • Cancer survivorship and care
  • Childhood Cancer Survivors' Quality of Life
  • Family Support in Illness
  • Reproductive tract infections research
  • Genital Health and Disease
  • Optimism, Hope, and Well-being
  • Palliative Care and End-of-Life Issues
  • Gout, Hyperuricemia, Uric Acid
  • Pharmacological Effects of Natural Compounds
  • Cervical Cancer and HPV Research
  • Antimicrobial Resistance in Staphylococcus
  • Minimally Invasive Surgical Techniques
  • Sexual function and dysfunction studies
  • Medicinal Plants and Neuroprotection
  • Health and Wellbeing Research
  • Morinda citrifolia extract uses
  • Inflammasome and immune disorders
  • Neurogenetic and Muscular Disorders Research
  • Posttraumatic Stress Disorder Research
  • Melanoma and MAPK Pathways
  • Axon Guidance and Neuronal Signaling
  • Uterine Myomas and Treatments
  • Mental Health and Well-being
  • Cell death mechanisms and regulation
  • Congenital Diaphragmatic Hernia Studies

Central South University
2023

China Medical University
2009-2022

First Hospital of China Medical University
2022

First Affiliated Hospital of Liaoning Medical University
2021

Fudan University Shanghai Cancer Center
2019

Shuguang Hospital
2017

Shanghai University of Traditional Chinese Medicine
2017

The University of Texas MD Anderson Cancer Center
2014

It is well known that cancer patients tend to have high levels of perceived stress and symptoms depression anxiety. However, there less study on the association between anxiety among ovarian in China. And mediating effect hope resilience needs be further studied. In this study, we aim examine prevalence symptoms, analyze anxiety, test whether mediate with Chinese cancer. A total 220 questionnaires were distributed collected from First Affiliated Hospital China Medical University Shengjing...

10.1186/s12955-017-0738-1 article EN cc-by Health and Quality of Life Outcomes 2017-08-17

Post-traumatic stress disorder (PTSD) symptoms can develop after person experiences one or more traumatic events. Little research, however, has been done on PTSD of patients with ovarian cancer. The present study aimed to estimate the prevalence in cancer China; effects demographic and clinical variables symptoms; multiple mediation roles association between social support China. We collected information first second hospitals China Medical University January 1, 2014 December 31, 2015....

10.1371/journal.pone.0177055 article EN cc-by PLoS ONE 2017-05-05

Objective This study aimed to compare the effects of robot-assisted thoracic surgery (RATS), video-assisted (VATS), and thoracotomy on psychological status, medical coping mode, quality life patients with lung cancer. Methods A total 158 cancer were selected from center a third-grade hospital in Hunan Province, China, September November 2020. The Self-Rating Anxiety Scale (SAS), Depression (SDS), Medical Coping Modes Questionnaire (MCMQ), Outcomes Study (MOS) 36-item Short Form Health Survey...

10.3389/fpsyg.2023.1039501 article EN cc-by Frontiers in Psychology 2023-03-27

Infection by human papillomavirus (HPV) is a necessary cause of cervical cancer. The purpose this study was to investigate the prevalence and genotype distribution HPV infection in Chinese women who were asymptomatic for diseases. Cervical cytology samples collected from 6479 Liaoning province, tested various genotypes using chip hybridization assay. found 10.3% all studied, with high risk (HR HPV) low (LR being 9.5% 1.1%, respectively. 16, 52, 58 most frequently HR positive women, present...

10.1002/jmv.24029 article EN Journal of Medical Virology 2015-04-16

Abstract BACKGROUND Hirschsprung disease (HSCR) is a congenital disorder characterized by an absence of intrinsic ganglion cells in the nerve plexuses lower colon. The Semaphorin 3A ( SEMA3A ) gene involved migration enteric neural precursors (ENPs). To analyze function HSCR, expression different colon segments HSCR was examined. METHODS levels both ganglionic and aganglionic tissues 32 patients with tissue 5 newborn unaffected individuals were examined real‐time RT‐PCR, Western‐blot,...

10.1002/bdra.20837 article EN Birth Defects Research 2011-06-08

Abstract This study aims to evaluate HR‐HPV viral load in the cervical lesion assessment and its diagnostic value on triage of ASCUS. The three‐step protocol for cancer screening was carried out 5171 patients from June 2017 August 2019, 1620 histopathological results were obtained. positive rate TCT increased with aggravation pathological grades lesions. sensitivity specificity (DH3) detect CIN II+ 91.91% 84.46%, respectively. In comparison, corresponding cytology test 80.51% 83.12%....

10.1002/cam4.3653 article EN cc-by Cancer Medicine 2021-03-07

A series of N ‐(9,10‐anthraquinone‐2‐carbonyl)amino acid derivatives ( 1a–j ) was designed and synthesized as novel xanthine oxidase inhibitors. Among them, the L / D ‐phenylalanine 1d 1i ‐tryptophan 1e 1j were effective with micromolar level potency. In particular, derivative (IC 50 = 3.0 μ m 2.9 presented highest potency both more potent than positive control allopurinol 8.1 ). Preliminary SAR analysis pointed that an aromatic amino fragment, for example, phenylalanine or tryptophan,...

10.1111/cbdd.13156 article EN Chemical Biology & Drug Design 2017-12-02

ABSTRACT Objective: The aim of this study was to determine the factors associated with a feeling well-being using Edmonton Symptom Assessment Scale (ESAS)–Feeling Well-Being item (ESAS–FWB; where 0 = best and 10 worst) among advanced lung or non-colonic gastrointestinal cancer patients who were referred an outpatient palliative care clinic (OPCC). We also examined association performance on ESAS–FWB overall survival (OS). Method: reviewed records consecutive incurable presenting OPCC from 1...

10.1017/s1478951517000116 article EN Palliative & Supportive Care 2017-03-07

Abstract To better understand patients’ perspectives and preferences for sexual issues to provide information guide medical staff in delivering health care, an anonymous, cross-sectional survey of inpatient gynecologic cancer patients was conducted from April 2017 March 2018. The questionnaire consisted three parts: basic information, a history sexuality discussion, eight preference questions. A total 1192 were included, the median age 43 years. More than half had junior high school...

10.1007/s13187-019-01653-9 article EN cc-by Journal of Cancer Education 2019-12-05

Post-traumatic stress disorder (PTSD) can manifest in individuals following a traumatic event. There is paucity of studies focusing on PTSD symptoms ovarian cancer (OC) patients. This study aimed to investigate the association social support, mental adjustment and Chinese OC patients with view exploring whether could mediate relationship.A cross-sectional was conducted from January 2015 December 2016. A total 171 subjects were recruited effective response rate 81.3%. The Checklist-Civilian...

10.2147/prbm.s372660 article EN cc-by-nc Psychology Research and Behavior Management 2022-08-01

Abstract BackgroundPatients with ovarian cancer (OC) often suffer from depressive symptoms, but there is little research on coping style such as perceived social support and resilience. The aim of the present study was to explore whether resilience plays a mediating role between symptoms. MethodsA cross-sectional performed August 2018 March 2019. Perceived support, resilience, symptoms were measured Multi‐dimensional Scale Social Support (MSPSS), Center for Epidemiologic Studies-Depression...

10.21203/rs.3.rs-228614/v1 preprint EN cc-by Research Square (Research Square) 2021-02-16

With the continuous development of minimally invasive and precise surgical techniques, laparoscopic myomectomy has become a mainstream method due to its aesthetic outcomes rapid postoperative recovery. However, during myomectomy, clinicians often encounter unfavorable factors, such as limited vision, inaccurate suturing, difficulty in removing tumors, susceptibility fatigue operating position. In recent years, robot-assisted surgery been widely used gynecology. The advantages this technique,...

10.3390/jcm11113221 article EN Journal of Clinical Medicine 2022-06-05

199 Background: The aim of this study was to determine the association between feeling well-being (FWB, 0= best, 10= worst) and overall survival in advanced lung or non-colonic gastrointestinal patients who were referred an outpatient palliative care clinic (OPC). We also determined predictors severity moderate severe - presenting care. Methods: reviewed records consecutive with incurable cancer OPC. Edmonton Symptom Assessment System (ESAS) scores obtained at initial visit from Jan. 1,...

10.1200/jco.2014.32.31_suppl.199 article EN Journal of Clinical Oncology 2014-11-01
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