Laura Amaya‐Pascasio

ORCID: 0000-0003-1162-4209
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About
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Research Areas
  • Acute Ischemic Stroke Management
  • Stroke Rehabilitation and Recovery
  • Cerebrovascular and Carotid Artery Diseases
  • Venous Thromboembolism Diagnosis and Management
  • Long-Term Effects of COVID-19
  • Atrial Fibrillation Management and Outcomes
  • COVID-19 Clinical Research Studies
  • Muscle activation and electromyography studies
  • Sexual function and dysfunction studies
  • Trigeminal Neuralgia and Treatments
  • Functional Brain Connectivity Studies
  • Cardiovascular Health and Disease Prevention
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Peripheral Neuropathies and Disorders
  • Health Systems, Economic Evaluations, Quality of Life
  • Facial Nerve Paralysis Treatment and Research
  • Retinal and Optic Conditions
  • Neural and Behavioral Psychology Studies
  • Attention Deficit Hyperactivity Disorder
  • Transcranial Magnetic Stimulation Studies
  • Atherosclerosis and Cardiovascular Diseases
  • Intensive Care Unit Cognitive Disorders
  • COVID-19 and healthcare impacts
  • Coagulation, Bradykinin, Polyphosphates, and Angioedema
  • Intracranial Aneurysms: Treatment and Complications

University of Almería
2022-2025

Complejo Hospitalario Torrecárdenas
2021-2025

Hospital General Universitario Gregorio Marañón
2021-2023

Impaired cognitive flexibility is associated with the characteristic symptomatology of ADHD and OCD. However, mechanisms underlying learning under uncertainty in adults OCD or remain unclear. This study aimed to identify contingency-based a sample OCD, using probabilistic reversal task, functional near-infrared spectroscopy, computational modelling. 148 Spanish-speaking (43 53 52 healthy controls) completed task. Previously, we obtained resting-state connectivity (rsFC) record between...

10.1016/j.comppsych.2025.152589 article EN cc-by-nc-nd Comprehensive Psychiatry 2025-03-13

Objective To describe the spectrum of neurological complications observed in a hospital-based cohort COVID-19 patients who required assessment. Methods We conducted an observational, monocentric, prospective study with diagnosis hospitalized during 3-month period first wave pandemic tertiary hospital Madrid (Spain). diagnoses that arose after onset symptoms. These could be divided into different groups. Results Only 71 (2.6%) 2750 suffered at least one complication (77 total) timeframe...

10.1111/ene.14748 article EN European Journal of Neurology 2021-01-21

We examined the association between obesity and early-onset cryptogenic ischemic stroke (CIS) whether fat distribution or sex altered this association.This prospective, multi-center, case-control study included 345 patients, aged 18-49 years, with first-ever, acute CIS. The control group age- sex-matched stroke-free individuals. measured height, weight, waist circumference, hip circumference. Obesity metrics analyzed body mass index (BMI), waist-to-hip ratio (WHR), waist-to-stature (WSR), a...

10.1016/j.jstrokecerebrovasdis.2022.106380 article EN cc-by Journal of Stroke and Cerebrovascular Diseases 2022-02-19

Abstract Background and purpose The was to perform a nationwide epidemiological study of Guillain–Barré syndrome (GBS) in Spain, analysing background incidences seasonal variation trying identify incidence changes during the coronavirus disease 2019 (COVID‐19) years. Methods This an observational collecting all GBS diagnoses from National Epidemiological Surveillance Network collected by Ministry Health. Patients discharged with as main diagnosis admitted 2018–2021 were included. Data on...

10.1111/ene.16439 article EN cc-by-nc-nd European Journal of Neurology 2024-08-12
Jukka Putaala Nicolas Martinez‐Majander Michelle Leppert Lauri Tulkki Jani Pirinen and 89 more Heli Tolppanen Tomi Sarkanen Marko Virtanen Nina Jaakonmäki Pekka Jäkälä Marja Hedman Petra Redfors Odd Bech‐Hanssen Ulla Junttola Juha Huhtakangas Pauli Ylikotila Riikka Lautamäki Ulf Schminke Bettina von Sarnowski Raila Busch Nilüfer Yeşilot Mine Sezgin Ulrike Waje‐Andreassen Sahrai Saeed Ana Catarina Fonseca A De Paula Laura Amaya Pascasio Patricia Martínez‐Sánchez Janika Kõrv Piibe Muda Phillip Ferdinand Cheryl Oxley Diana Zakarkaitė Kristina Ryliškienė Alessandro Pezzini Carlo Lombardi Radim Líčeník Marialuisa Zedde Teresa Grimaldi Capitello Georgios Tsivgoulis Juha Sinisalo Eva Gerdts Turgut Tatlisumak Külliki Karu Liisa Kõrv Riina Vibo Mika Lehto J Rapola Tiina Sairanen Lauri Soinne Satu Suihko Marjaana Tiainen Suvi Tuohinen Jaana Autere Tuuli Miettinen Ossi Nerg Heikki Numminen Essi Ryödi Antti Saraste Jaana K. Huhtakangas Juha Huhtakangas Laura Kytövuori Alexandra Frogoudaki Georgios Papadimitripoulos Giovanni Malferrari Marina Colombi Marco Ritelli Aleksandra Ekkert Dalius Jatužis Rytis Masiliūnas Frank–Erik de Leeuw Merel S. Ekker Suzette E. Elias‐Smale Myrna Marita Elisabeth van Dongen Annette Fromm Ana G. Almeida Isabel Amorim José M. Ferro Victoria Mejias Olmedo Raúl Reyes Parrilla Evelin Rios Margareta Abrahamson Maria Davidson Lukas Holmegaard Mikael Jerndal Katarina Jood Annika Nordanstig Esme Ekizoğlu Turgut Zoltan Pencz Christine Roffe Mohammad Hacque Muhammad Khaled Hasan Peter Owusu‐Agyei Santhosh Subramonian

BACKGROUND: The incidence of young-onset ischemic stroke is rising, driven by cryptogenic (CIS) and patients without vascular risk factors. This study examines the burden associations modifiable traditional, nontraditional, female sex–specific factors with CIS, stratified clinically relevant patent foramen ovale (PFO), defined high-risk features atrial septal aneurysm or large right-to-left shunt. METHODS: We enrolled consecutive aged 18 to 49 years recent CIS frequency-matched stroke-free...

10.1161/strokeaha.124.049855 article EN Stroke 2025-04-17

<b><i>Introduction:</i></b> We analyzed whether the coronavirus disease 2019 (COVID-19) crisis affected acute stroke care in our center during first 2 months of lockdown Spain. <b><i>Methods:</i></b> This is a single-center, retrospective study. collected demographic, clinical, and radiological data; time course; treatment patients meeting unit admission criteria from March 14 to May 14, 2020 (COVID-19 period group). Data were compared with...

10.1159/000514140 article EN other-oa Cerebrovascular Diseases 2021-01-01

Recent research has highlighted an increased incidence of ischemic stroke (IS) in young adults, along with a higher percentage vascular risk factors at younger ages. This study aimed to estimate the in-hospital IS and associated comorbidities by sex age group Spain. A retrospective analysis Spain Nationwide Inpatient Sample database from 2016 2019 was conducted, which included adult patients IS. In-hospital mortality rates were estimated, descriptive main performed, stratified groups. total...

10.3390/jpm13050768 article EN Journal of Personalized Medicine 2023-04-29

Microvascular decompression is considered to be the most effective and only etiological surgical treatment for classical trigeminal neuralgia, relieving neurovascular compression found in up 95% of cases. This study aims report long-term outcomes identify prognostic factors a series patients with neuralgia treated by microvascular decompression.

10.1016/j.nrl.2021.03.009 article EN cc-by-nc-nd Neurología 2021-05-26

Background and Purpose An individual selection of ischemic stroke patients at higher risk atrial fibrillation (AF) might increase the diagnostic yield prolonged cardiac monitoring render it cost-effective. Methods The clinical, laboratory, brain/cardiac imaging characteristics consecutive without documented AF were recorded. All underwent least 72 h unless was diagnosed before, transthoracic echocardiogram, blood biomarkers, intracranial vessels imaging. A predictive grading developed by...

10.3389/fneur.2022.900582 article EN cc-by Frontiers in Neurology 2022-06-28

The benefits of the PCSK9 inhibitors, alirocumab and evolocumab, in lowering LDL-cholesterol preventing major adverse cardiac events (MACE) have been demonstrated pivotal clinical trials. However, few studies routine practice conducted to analyse compare efficacy safety two drugs.Retrospective observational study patients treated with a inhibitor five hospitals Andalusia (southern Spain). Baseline demographic data, levels occurrence MACEs during follow-up period were recorded.A total 141...

10.1016/j.athplu.2021.08.009 article EN cc-by-nc-nd Atherosclerosis Plus 2021-10-04

Abstract Rationale In-stent reocclusion after endovascular therapy has a negative impact on outcomes in acute ischemic stroke (AIS) due to tandem lesions (TL). Optimal antiplatelet approach these patients avoid in-stent is yet be elucidated. Aims To assess efficacy and safety of intravenous tirofiban versus aspirin undergoing MT plus carotid stenting the setting AIS TL. Sample size estimates Two hundred forty will enrolled, 120 every treatment arm. Methods design A multicenter, prospective,...

10.1186/s13063-023-07817-9 article EN cc-by Trials 2024-01-09

ABSTRACT OBJECTIVE To perform a nationwide epidemiological study of Guillain-Barré syndrome (GBS) in Spain, analysing background incidences and seasonal variation trying to identify incidence changes during the COVID-19 years. METHODS Observational collecting all GBS diagnoses from National Epidemiological Surveillance Network (RENAVE) collected by Ministry Health. Patients discharged with as main diagnosis admitted 2018-2021 were included. Data on SARS-CoV-2 infections vaccinations obtained...

10.1101/2024.03.27.24304897 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2024-03-28

Stroke is the leading cause of disability and second death worldwide. The increasing burden stroke underscores importance optimising rehabilitation protocols. Virtual reality (VR) can improve poststroke prognosis. A VR software combining gamification, full immersion specificity (ie, Development validation a novel viRtual rEality for improving diSability quality lifE in patients with sTroke (RESET) software) might substantially life (QoL). However, this technology still very scarce. RESET...

10.1136/bmjsem-2024-002123 article EN cc-by-nc BMJ Open Sport & Exercise Medicine 2024-08-01

Background: Stroke is the second cause of mortality worldwide and first in women. The aim this study to develop a predictive model estimate risk admission patients who have not received reperfusion treatment. Methods: A retrospective cohort was conducted clinical–administrative database, reflecting all cases non-reperfused ischaemic stroke admitted Spanish hospitals during period 2008–2012. based on logistic regression developed training later validated by “hold-out” method. Complementary...

10.3390/ijerph19063182 article EN International Journal of Environmental Research and Public Health 2022-03-08

Microvascular decompression is considered to be the most effective and only etiological surgical treatment for classical trigeminal neuralgia, relieving neurovascular compression found in up 95% of cases. This study aims report long-term outcomes identify prognostic factors a series patients with neuralgia treated by microvascular decompression.A retrospective observational 152 consecutive operated at least six months follow-up. The results, including pain relief according Barrow...

10.1016/j.nrleng.2021.03.010 article EN cc-by-nc-nd Neurología (English Edition) 2023-11-01

Abtract The probabilistic reversal learning paradigm is one of the most used to assess cognitive flexibility during a contingency-based process. Lack related symptomatology that characterizes disorders such as Attention-Deficit/Hyperactivity Disorder (ADHD) and Obsessive-Compulsive (OCD). Resting-state functional connectivity (rsFC) could be specific predictor performance in flexibility. However, mechanisms underlying an environment uncertainty with OCD or ADHD adults have not been widely...

10.1101/2024.01.17.24301365 preprint EN medRxiv (Cold Spring Harbor Laboratory) 2024-01-17

Our aim was to compare the stroke outcomes of a direct transfer (DT) thrombectomy-capable center vs. initial care at two local centers: nearby hospital (NH, 36 km) and distant (DH, 113 km). Patients who underwent mechanical thrombectomy were analyzed (February 2017–October 2021), outcome considered favorable if modified Rankin scale (mRS) score ≤ 2 three months. A total 300 patients included, 55 which transferred from NH 58 DH. There difference in median (IQR) time 39 min between hospitals...

10.3390/jpm14040395 article EN Journal of Personalized Medicine 2024-04-08

The evolution of ischemic stroke is different accordin'g to sex and one the main causes death in women. Previous studies have shown that women are less likely receive acute treatment, center type an important predictor door-to-needle times. We investigated whether attended a similar way men telestroke network with specialized physicians.

10.1089/heq.2023.0175 article EN cc-by Health Equity 2024-05-01
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