A5059597394- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Lipoproteins and Cardiovascular Health
- Cardiovascular Function and Risk Factors
- Aortic Disease and Treatment Approaches
- Peripheral Artery Disease Management
- Infective Endocarditis Diagnosis and Management
- Cerebrovascular and Carotid Artery Diseases
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Venous Thromboembolism Diagnosis and Management
- COVID-19 and healthcare impacts
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Systems, Economic Evaluations, Quality of Life
- Heart Failure Treatment and Management
- Medication Adherence and Compliance
- Nitric Oxide and Endothelin Effects
- ECG Monitoring and Analysis
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Health and Disease Prevention
- Mechanical Circulatory Support Devices
University of Naples Federico II
2020-2025
Federico II University Hospital
2020-2025
Onze Lieve Vrouwziekenhuis Hospital
2022-2024
Azienda Ospedaliera S.Giuseppe Moscati
2024
Cardiovascular Research Center
2024
Ospedale Annunziata di Cosenza
2024
Ceinge Biotecnologie Avanzate (Italy)
2024
Flanders Environment Agency
2023
Centre Hospitalier Universitaire de Tivoli
2008-2022
Tecnologie Avanzate (Italy)
2021
Abstract Aims A majority of acute coronary syndromes (ACS) present without typical ST elevation. One-third non–ST-elevation myocardial infarction (NSTEMI) patients have an acutely occluded culprit artery [occlusion (OMI)], leading to poor outcomes due delayed identification and invasive management. In this study, we sought develop a versatile artificial intelligence (AI) model detecting OMI on single-standard 12-lead electrocardiograms (ECGs) compare its performance with existing...
Acute type A aortic dissection (AAAD) remains one of the most challenging diseases in cardiothoracic surgery, and despite numerous innovations, early mortality still high. The aim this study was to review Emilia-Romagna experience treatment AAAD evaluate effect malperfusion on morbidity. We examined data 502 patients between January 2000 December 2008, from Regional Registry AAAD. mean age 62.4 ± 13 years 66.5% were male. At presentation, various types syndromes (cerebral, cardiac,...
BACKGROUND: Coronary computed tomography angiography (CCTA) is emerging as a valuable tool for noninvasive surveillance of cardiac allograft vasculopathy (CAV) in patients with heart transplant (HTx). We assessed the diagnostic performance comprehensive CCTA-based approach compared invasive reference, which includes coronary angiography, intravascular ultrasound, and fractional flow reserve, detecting CAV. METHODS: This was multicenter prospective study including 37 HTx who underwent CCTA,...
Coronary microvascular dysfunction (CMD) is involved in heart failure (HF) onset and progression, independently of HF phenotype obstructive coronary artery disease. Invasive assessment CMD might provide insights into phenotyping prognosis patients with HF. We aimed to assess absolute flow, resistance, myocardial perfusion, flow reserve, resistance reserve preserved ejection fraction reduced (HFrEF).
The impact of final kissing balloon inflation (FKB) in patients treated with an upfront provisional strategy for coronary bifurcation lesions is controversial. We aimed to assess the FKB on patient- and lesion-oriented outcomes a large real-world cohort. ULTRA-BIFURCAT registry was obtained by patient-level merging BIFURCAT ULTRA registries. Pairs were generated propensity score matching (PSM). primary outcome interest major adverse cardiac events (MACE) - composite all-cause death,...
Abstract Background Data about the long‐term performance of new‐generation ultrathin‐strut drug‐eluting stents (DES) in challenging coronary lesions, such as left main (LM), bifurcation, and chronic total occlusion (CTO) lesions are scant. Methods The international multicenter retrospective observational ULTRA study included consecutive patients treated from September 2016 to August 2021 with (<70 µm) DES de novo lesions. Primary endpoint was target lesion failure (TLF): composite cardiac...
Severe aortic stenosis (AS) is associated with left ventricular (LV) remodelling, likely causing alterations in coronary blood flow and microvascular resistance.
Background Cardiovascular disease (CVD) is one of the leading causes death in Belgium. Current strategies for prevention and management CVD focus on reducing low-density lipoprotein cholesterol (LDL-C) levels. This analysis assessed whether LDL-C goals, recommended by European Society Cardiology (ESC)/European Atherosclerosis (EAS) guidelines, were being achieved a Belgian study population.Methods The cross-sectional, observational, DA VINCI enrolled patients prescribed lipid-lowering...
Abstract Background Angiography‐derived fractional flow reserve (virtual FFR) has shown excellent diagnostic performance compared with wire‐based FFR. However, virtual FFR pullback curves have not been validated yet. Objectives To validate the accuracy of to pullbacks and assess their clinical utility using patient‐reported outcomes. Methods Pooled analysis two prospective studies, including patients hemodynamically significant (FFR ≤ 0.80) coronary artery disease (CAD). Virtual were...
(1) Aims: We sought to assess the impact of extent cardiac damage on survival among real-world patients with severe aortic stenosis (AS) undergoing transcatheter valve implantation (TAVI). (2) Methods: A staging classification was applied 262 from EffecTAVI Registry at baseline and re-assessed within 30-days after TAVI. The primary endpoint study all-cause mortality 1-year. Secondary endpoints included cerebrovascular accident, myocardial infarction, permanent pacemaker implantation,...
Abstract Dobutamine stress echocardiography (DSE) is sensitive but subjective diagnostic tool to detect inducible ischemia. Nowadays, speckle tracking allows an objective quantification of regional wall function. We aimed investigate the feasibility and accuracy global (GLS) longitudinal strain (RLS) during DSE significant coronary stenosis (SCS). conducted a prospective observational multicenter study including patients undergoing for suspected SCS. 50 with positive underwent angiography....
Limited data exist on ultrathin-strut drug-eluting stent (ultrathin DES) performance in DES in-stent restenosis (ISR).
Few data are available on polymer-free drug-eluting stents in patients undergoing percutaneous coronary intervention (PCI). We aimed to determine the efficacy and safety of a amphilimus-eluting stent (AES), using reservoir-based technology for drug delivery, compared with biodegradable-polymer everolimus-eluting (EES). This was randomised, investigator-initiated, assessor-blind, non-inferiority trial conducted at 14 hospitals Italy (ClinicalTrials.gov: NCT04135989). All-comer PCI were...