- Colorectal Cancer Surgical Treatments
- Hernia repair and management
- Esophageal and GI Pathology
- Intraperitoneal and Appendiceal Malignancies
- Ovarian cancer diagnosis and treatment
- Diverticular Disease and Complications
- Appendicitis Diagnosis and Management
- Colorectal and Anal Carcinomas
- Gastric Cancer Management and Outcomes
- Endometrial and Cervical Cancer Treatments
- Gastrointestinal disorders and treatments
- Gastroesophageal reflux and treatments
- Pelvic and Acetabular Injuries
- Anorectal Disease Treatments and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Eosinophilic Esophagitis
- Uterine Myomas and Treatments
- Biliary and Gastrointestinal Fistulas
- Gallbladder and Bile Duct Disorders
- Gastrointestinal Tumor Research and Treatment
- Intestinal and Peritoneal Adhesions
- Surgical Simulation and Training
- Teratomas and Epidermoid Cysts
- Ubiquitin and proteasome pathways
- PI3K/AKT/mTOR signaling in cancer
University of Naples Federico II
2000-2023
Federico II University Hospital
2011-2021
Agostino Gemelli University Polyclinic
2021
Azienda Ospedaliero-Universitaria Cagliari
2021
University of Cagliari
2021
University of Chieti-Pescara
2021
University of Insubria
2021
University of Rome Tor Vergata
2009
Abstract Background Since the introduction of minimally invasive surgery, new techniques like transabdominal preperitoneal (TAPP) repair have progressively gained acceptance for treatment groin hernia. Laparoscopic TAPP (LTAPP) is recommended bilateral repairs. Likewise, robotic platforms has promised additional surgical benefits (RTAPP), which are yet to be confirmed. This study compared multicenter data obtained from patients undergoing inguinal hernia with RTAPP, performed during...
N-Acylethanolamine acid amidase (NAAA) is a lysosomal enzyme accountable for the breakdown of N-acylethanolamines (NAEs) and its pharmacological inhibition has beneficial effects in inflammatory conditions. The knowledge NAAA cancer fragmentary with an unclarified mechanism, whereas contribution to colorectal (CRC) unknown date.CRC xenograft azoxymethane models were used assess vivo effect inhibition. Further, tumour secretome was evaluated by oncogenic array, CRC cell lines vitro studies,...
Background. Microsurgery has quickly become the "gold standard" approach for vascular surgical steps during neurosurgery. However, despite its advantages, microscope not been widely adopted in general surgery. A new 3D-surgical exoscope, ORBEYETM, developed and introduced to some specialties. Herein, we present our preliminary experience with ORBEYETM exoscope as applied a number of procedures. Method. Throughout February 2020, 7 patients had undergone varying procedures at institute...
Neoadjuvant chemoradiotherapy has a significant role in downstaging cancer. It improves the local control of disease and can make conservative resection rectal cancer possible.We enrolled 114 patients with subperitoneal who underwent neoadjuvant chemoradio-therapy radical excision total mesorectal (TME). The primary endpoint was oncological outcomes secondary surgical outcomes.We evaluate experience multidisciplinary team integrated treatment rectum.Surgical procedures performed were...
Background: Tailgut cysts are rare congenital lesions that develop in the presacral space. As they can potentially conceal primary neuroendocrine tumors, surgical excision is suggested as treatment of choice. However, specific management guidelines have yet to be developed. A posterior approach usually preferred for extending third sacral vertebral body. Conversely, a transabdominal upward achieve an optimal view field and avoid injuries. Case report: Here, we report case 48-year-old man...
Anastomotic leakage is the most-feared complication of rectal surgery. Transanal devices have been suggested for anastomotic protection as an alternative to defunctioning stoma, although evidence conflicting, and no single device widely used in clinical practice. The aim this paper investigate safety efficacy a transanal tube prevention following laparoscopic cancer resection. A was cases total mesorectal excision with low colorectal or coloanal anastomosis, undamaged doughnuts, negative...
Abstract Tumours of the small intestine are rare and account for about 5% gastrointestinal tract neoplasms. The angle Treitz (AT) could be defined as intestinal loop comprised between third duodenal portion first 10 cm jejunum. A gold standard surgical treatment AT neoplasm has not yet been well defined. This paper is focused on a very disease at best our knowledge this largest case series in literature Laparoscopic Segmental Resection (LSR) tumours. Using prospectively collected database,...
The inferior mesenteric artery (IMA) preservation in elective laparoscopic left colectomy for diverticular disease may reduce the risk of anastomotic leakage. However, an increased bleeding is assumed. aim this study was to investigate colorectal anastomosis when IMA resected or preserved during colectomy.A retrospective a prospectively collected database performed. All patients who underwent colectomy, from December 2018 September 2020 were included. Patients' data and clinical information...
The creation of the pneumoperitoneum is first step for any minimally invasive surgical procedure. Although rare, iatrogenic vascular or visceral injuries are reported and they mainly related to insertion trocar. Open Veress Assisted (OVA) technique allows a safe maneuver trocar in order minimize risk intraoperative complications during positioning purpose this study was describe OVA discuss use our current practice.Each described text. A retrospective review prospectively maintained...
Background and Objectives The incidence of locoregional recurrences (LR) following radical surgery rectal cancer varies from 5% to 30% according the literature. purpose this prospective study was compare outcome Abdomino-Perineal Excision (APE) vs. Anterior Resection (AR) in a consecutive series 188 patients who underwent for cure 1980 end 1992 (81 APE 107 AR), followed 5 years, evaluating their influence on recurrences. Methods were enrolled at random two surgical groups, provided that...