The aim of this study is to describe the health status, care received, and their impact on quality life in patients with hemophilia. Patients severe factor VIII or IX deficiency without inhibitors other chronic disease were enrolled. Turkish version Hemophilia-Specific Quality Life Index (Haemo-QoL) questionnaire was administered pediatric aged 4 16 years Haem-A-QoL adult patients. Joints evaluated according World Federation Hemophilia (WFH) orthopedic joint scores.Thirty-nine...

In most perinatal-hypoxia survivors, myocardial dysfunction can be reversed with appropriate inotropic support and oxygenation. The main problem related to outcome is cerebral damage.We tested the hypothesis that cardiac troponin I (cTnI), a known marker of injury, also an early predictor severity damage mortality in intrauterine hypoxia.Venous arterial cord blood samples were collected at delivery from 54 consecutive newborns hypoxic-ischemic encephalopathy 50 healthy controls. Arterial gas...

To evaluate the effect of domperidone use on corrected QT interval in premature infants.A prospective study infants receiving was included this study. A baseline electrocardiogram obtained just before and 3, 7 14 days after initiation domperidone. Corrected considered prolonged if it exceeded upper limit for age.A total 40 were enrolled The mean birth weight 1109+/-332 g, gestational age 28.8+/-2.4 years at onset 32.8+/-2 days. No difference observed between start treatment. Two had...

This present study was undertaken to determine the levels of malondialdehyde (MDA), nitric oxide (NO) and total antioxidant status (TAS) in testes adolescent rats with experimental bilateral varicocele effects oxidative stress on testis produced by varicocele.6-week-old, male Wistar rats, weighing 146-334 g (228.37 +/- 41.34 g), were randomly allocated into two groups. The first group underwent selective partial ligation spermatic vein (n = 28), second a sham operation served as controls...

There is a paucity of data on lung physiology in late-preterm children, who may be exposed to risk decline function during childhood. In this study, we evaluated preschool children born late preterm using impulse oscillometry (IOS), and compared the results with those obtained healthy term-born children.Children between 3 7 years age were being followed up at outpatient clinic included as group. Age-matched served controls. A total 90 75 study. At 5-20 Hz, resistance (R5-R20), reactance...

This study examined potential risk factors for and consequences of simple minor neurological dysfunction (SMND), in a group very low-birthweight newborns followed until preschool age.This was prospective longitudinal study. Children with birthweight <1500 g were assessed at 4-6 years age. Twenty-eight children normal examination 35 SMND included the final analysis. Risk development its association certain neuropsychiatric conditions studied.Based on neonatal data, SMND, Apgar score 1 min...

OBJECTIVE To investigate the possible protective role of insulin‐like growth factor‐1 (IGF‐1, reported to have a effect in experimental models hypoxic ischaemia), and involvement apoptotic cell death model torsion/detorsion rat testis. MATERIALS AND METHODS Adult male Wistar rats were divided into five groups each. Group 1 underwent sham operation as control; group 2 testis was twisted 3 then untwisted; 4 IGF‐1 injected subcutaneously just before bilateral torsion, right removed after h left...

Objectives: The aims of this study were to (a) establish a reference range for cardiac troponin I (cTnI) in the cord blood healthy infants, and (b) investigate effect Apgar score, gas, gestational age, creatine kinase (CK) MB (CK-MB) fraction levels on cTnI levels. Methods: 112 perinatal hypoxic 84 control newborns without hypoxia enrolled study. Cord samples collected from babies arterial gas analysis, cTnI, CK CK-MB measurements. Gestational birth weight, sex, score history fetal distress...

In our country, tricyclic antidepressants are usually present in most of the homes. Myocardial depression and ventricular arrhythmia severe side effects antidepressant overdose. A 4-year-old boy was brought to hospital after taking 70 mg/kg amitriptyline. On arrival, patient comatose (Glasgow Coma Score 3), had a shallow breathing pattern with bradycardia (HR <30/min), hypotension. He intubated resuscitated multiple doses adrenaline sodium bicarbonate. infused bolus 20 normal saline for...

Premature infants < 1500 g were randomly assigned to study and control groups. In the group, 42 premature received recombinant human erythropoietin (r-Hu EPO) 750 U/kg per week subcutaneously from day 5 40 enteral iron supplementation of 2 6 mg/kg/d beginning on 14 provided that they receiving at least 50% energy intake orally. 51 same dose end fourth week. At a 12-week monitoring period, r-Hu EPO combined with early reduced transfusion needs only in subgroup 1000 g. treatment had no effect...

There are several studies that have shown an increased risk of premature birth and developmental abnormalities with in vitro fertilization (IVF); however, the data on preterm mortality morbidity limited. Our aim is to investigate whether IVF had effect neonates admitted neonatal intensive care unit. A total 940 term babies who were unit over a period 2 years enrolled. Of these, 121 born after 810 natural conception 9 ovulation induction. 112 405 conception. In group, gestational age weight...

The purpose of this study was to determine the role intravenous immunoglobulin (IVIG) administration in preterm neonates with S. typhimurium infection. A randomized trial 47 intestinal or extraintestinal tymphimurium infection performed. Neonates were randomly divided into two groups: 22 only given cefoperazone (group 1); 25 plus IVIG 2). at a dose 500 mg/kg on days 1, 2, 3, and 8 after entry study. Following treatment, bacteremia, complications, mortality rate, recovery time, duration...

There have been many studies that investigated the risk factors of mortality in preterm infants, but none has shown an association between and exposure to heavy metals or trace elements. The aim this study was therefore measure levels toxic (lead, cadmium) elements (zinc, iron, copper) meconium samples elucidate their with mortality.Metals were measured 304 infants using a flame atomic absorption spectrophotometer.The level non-surviving significantly higher than surviving infants. Moreover,...

The aim of this study was to investigate the genotypic distribution organic anion transporting polypeptide 2 (OATP-2) gene mutations and relationship with hyperbilirubinemia unknown etiology. Polymerase chain reaction, restriction fragment length polymorphism, agarose gel electrophoresis techniques were used for detection OATP-2 in 155 newborn infants: 37 unexplained hyperbilirubinemia, 65 explained 53 without hyperbilirubinemia. In gene, we identified A→G transitions at nucleotide positions...

The numbers of patients with chronic prostatitis are increasing in all countries. aim this study was to determine the prevalence chlamydia non-bacterial prostatitis. Fifty-five suffering back pain, discomfort on voiding and ejaculation perineal ache, 35 normal patients, were examined between December 1995 July 1997. Urine samples prostatic secretions after prostate massage collected from patients. Chlamydia antigens tested for Chlamyphast. antigen positive 14 55 (25.4%) prostatitis, but only...

Peyronie’s disease is an ill-defined condition that often leads to severe penile deformity and sometimes erectile dysfunction. Penile Doppler studies indicate veno-occlusive dysfunction as the principal cause of poor rigidity in patients. Diabetes mellitus also a known impotence its prevalence tended be higher patients with disease. We evaluated 143 disease, 92 impotent men (37 diabetic, 55 nondiabetic) control group. vascular were performed on each was investigated Veno-occlusive found main...