A5063751388- Neonatal Respiratory Health Research
- Infant Nutrition and Health
- Neonatal and Maternal Infections
- Neonatal and fetal brain pathology
- Breastfeeding Practices and Influences
- Streptococcal Infections and Treatments
- Respiratory Support and Mechanisms
- Neuroscience of respiration and sleep
- Cytomegalovirus and herpesvirus research
- Infant Development and Preterm Care
- Neonatal Health and Biochemistry
- Pneumonia and Respiratory Infections
- Acute Myocardial Infarction Research
- Child Nutrition and Water Access
- Hepatitis C virus research
- Congenital Diaphragmatic Hernia Studies
- Herpesvirus Infections and Treatments
- Hepatitis B Virus Studies
- Turkish Urban and Social Issues
- RNA regulation and disease
- Metabolism and Genetic Disorders
- Assisted Reproductive Technology and Twin Pregnancy
- Respiratory viral infections research
- Thyroid Disorders and Treatments
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
Kocaeli Üniversitesi
2012-2023
Sağlık Bilimleri Üniversitesi
2021
Sivas Cumhuriyet Üniversitesi
2021
Maltepe University
2008
Pediatrics and Genetics
2005
Inonu University
1994-1996
Baylor College of Medicine
1994-1995
Texas Children's Hospital
1994-1995
Elazığ Eğitim ve Araştırma Hastanesi
1992
Neonatal infections are a major cause of morbidity and mortality in the first month life, especially developing countries. Despite advances neonatology, neonatal still haves clinical importance because nonspecific signs symptoms, no perfect diagnostic marker, interference with non-infectious diseases newborns. Diagnosis is typically made by laboratory findings. Empiric antibiotic therapy should be started newborn symptoms infection after cultures taken according to time risk factors,...
Thyroid dysgenesis is the most frequent cause of congenital hypothyroidism (CH), and its genetic basis largely unknown. Hitherto, two mutations in human thyroid transcription factor 2 (TTF-2) gene have been described unrelated cases CH with cleft palate, spiky hair, variable choanal atresia, complete agenesis. Here, we describe a novel TTF-2 mutation female child resulting syndromic absence agenesis.The index case homozygous for an arginine to cysteine (R102C) highly conserved residue within...
Hypoxic ischemic encephalopathy (HIE) is a significant cause of mortality and short- long-term morbidities. Therapeutic hypothermia (TH) has been shown to be the standard care for HIE infants ≥36 weeks gestational age (GA), as it demonstrated reduce rates mortality, adverse neurodevelopmental outcomes. This study aims determine incidence in our country, assess TH management with HIE, present short-term outcomes these infants.The Turkish Ischemic Encephalopathy Online Registry database was...
In most perinatal-hypoxia survivors, myocardial dysfunction can be reversed with appropriate inotropic support and oxygenation. The main problem related to outcome is cerebral damage.We tested the hypothesis that cardiac troponin I (cTnI), a known marker of injury, also an early predictor severity damage mortality in intrauterine hypoxia.Venous arterial cord blood samples were collected at delivery from 54 consecutive newborns hypoxic-ischemic encephalopathy 50 healthy controls. Arterial gas...
To evaluate the effect of domperidone use on corrected QT interval in premature infants.A prospective study infants receiving was included this study. A baseline electrocardiogram obtained just before and 3, 7 14 days after initiation domperidone. Corrected considered prolonged if it exceeded upper limit for age.A total 40 were enrolled The mean birth weight 1109+/-332 g, gestational age 28.8+/-2.4 years at onset 32.8+/-2 days. No difference observed between start treatment. Two had...
Hyperglycemia has become an important risk factor for mortality and morbidity in the neonatal period, especially with increased survival rates of very low birth weight neonates. period develops as a result various mechanisms including iatrogenic causes, inability to supress hepatic glucose production, insulin resistance or intolerance, specifically preterm Initiation parenteral enteral feeding early babies increases production sensitivity. The plasma is targeted be kept between 70 150 mg/dL...
This national cross-sectional survey aimed to assess the iodine status in pregnant women and their offspring, also demonstrate regional differences by measuring urinary concentration (UIC). For each woman her newborn a questionnaire was prepared with basic facts as age, parity number or birth weight additional information regarding thyroid diseases, use of iodized salt household, extra supplementation during pregnancy, education level wage income. The target population represented 1444 who...
There is a paucity of data on lung physiology in late-preterm children, who may be exposed to risk decline function during childhood. In this study, we evaluated preschool children born late preterm using impulse oscillometry (IOS), and compared the results with those obtained healthy term-born children.Children between 3 7 years age were being followed up at outpatient clinic included as group. Age-matched served controls. A total 90 75 study. At 5-20 Hz, resistance (R5-R20), reactance...
This study examined potential risk factors for and consequences of simple minor neurological dysfunction (SMND), in a group very low-birthweight newborns followed until preschool age.This was prospective longitudinal study. Children with birthweight <1500 g were assessed at 4-6 years age. Twenty-eight children normal examination 35 SMND included the final analysis. Risk development its association certain neuropsychiatric conditions studied.Based on neonatal data, SMND, Apgar score 1 min...
Hypoglycemia is one of the most important and common metabolic problems newborn because it poses a risk neurological injury, if prolonged recurs. Therefore, newborns who carry hypoglycemia should be fed immediately after delivery blood glucose level measured with intervals 2-3 hours from 30th minute feeding. The threshold value for 40 mg/dL first 24 in symptomatic babies. In asymptomatic babies, this considered 25 0-4 hours, 35 mg/dl 4-24 50 60 48 hours. Screening performed bed-side test...
Objectives: The aims of this study were to (a) establish a reference range for cardiac troponin I (cTnI) in the cord blood healthy infants, and (b) investigate effect Apgar score, gas, gestational age, creatine kinase (CK) MB (CK-MB) fraction levels on cTnI levels. Methods: 112 perinatal hypoxic 84 control newborns without hypoxia enrolled study. Cord samples collected from babies arterial gas analysis, cTnI, CK CK-MB measurements. Gestational birth weight, sex, score history fetal distress...
To investigate fetal exposure to toxic metals [lead (Pb), cadmium (Cd)] and levels of trace elements [zinc (Zn), copper (Cu), iron (Fe)] in newborns from an industrial city. Relationships between meconium mineral contents parental occupation location residence were also tested.The 117 healthy newborn infants measured by flame atomic absorption spectrophotometer.The median concentrations (interquartile range) the as follows: Pb: 46.5 (1,399) microg/g dry weight (wt), Cd: 2.3 (55.6) wt; Zn:...
There are several studies that have shown an increased risk of premature birth and developmental abnormalities with in vitro fertilization (IVF); however, the data on preterm mortality morbidity limited. Our aim is to investigate whether IVF had effect neonates admitted neonatal intensive care unit. A total 940 term babies who were unit over a period 2 years enrolled. Of these, 121 born after 810 natural conception 9 ovulation induction. 112 405 conception. In group, gestational age weight...
Aim: To determine the value of cord blood cardiac troponin I levels (cTnI) as an early prognostic factor in critically ill newborns, and to compare cTnI with score for neonatal acute physiology (SNAP).
Late-preterm delivery is known to be associated with potential adverse effects on lung development. Passive smoking may result in alterations of pulmonary function infants born late-preterm. Impulse oscillometry (IOS) a noninvasive, rapid, and practicable technique that can assess function. This study aimed evaluate the effect passive tests preschool children late-preterm using IOS.The population consisted total 139 between 3 7 years age who were being followed-up at our outpatient unit time...
We reviewed the isolation of fungi from cerebrospinal fluid (CSF) cultures at Texas Children's Hospital during past 6 years to evaluate significance a positive culture and identify potential risk factors. Thirty-seven fungal isolates were recovered 23 patients representing 2% all 1498 CSF for study period. Candida species accounted 94.5% isolates. Nine newborns 8 these very low birth weight premature neonates. C. albicans was newborns. Eleven children 4 months 14 old. Three had obtained on...
Objective: Surfactant administration is usually performed by endotracheal intubation under mechanical ventilation. Less invasive surfactant (LISA) technique has became widespread in recent years, order to prevent the risk of barotrauma and volutrauma caused ventilation intubation. The aim this prospective study evaluate effectiveness via a thin catheter during spontaneous breathing on NIPPV compare with INSURE method. Method: Seventy-eight preterm infants who were born at university hospital...
Late neonatal hypocalcemia (LNH) is a common metabolic problem associated with hypoparathyroidism, high phosphate intake and vitamin D deficiency, often presenting seizures. In this cross-sectional study, we aimed to evaluate the role of deficiency in LNH Turkey describe characteristics affected newborns.Conducted design participation 61 centers from December 2015 2016, study included term neonates (n=96) their mothers (n=93). Data were registered on FAVOR Web Registry System. Serum samples...