A5091101097- Neonatal Respiratory Health Research
- Neonatal and fetal brain pathology
- Neuroscience of respiration and sleep
- Thyroid Disorders and Treatments
- Pediatric Urology and Nephrology Studies
- Neonatal Health and Biochemistry
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Fetal and Pediatric Neurological Disorders
- Diabetes Management and Research
- Respiratory Support and Mechanisms
- COVID-19 Impact on Reproduction
- Traumatic Brain Injury and Neurovascular Disturbances
- Oral microbiology and periodontitis research
- Inflammatory Biomarkers in Disease Prognosis
- Neurological and metabolic disorders
- Retinopathy of Prematurity Studies
- Pancreatitis Pathology and Treatment
- Metabolism and Genetic Disorders
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Dental Health and Care Utilization
- Infectious Encephalopathies and Encephalitis
- Systemic Lupus Erythematosus Research
- Infant Nutrition and Health
- Genomic variations and chromosomal abnormalities
- Respiratory and Cough-Related Research
Adnan Menderes University
2016-2024
Istanbul Aydın University
2021
Ege University
2020
Izmir University
2020
Objectives To predict the risk of retinopathy prematurity (ROP) development according to routine complete blood count (CBC) parameters. Materials and Methods The medical records CBC results 150 premature neonates were retrospectively evaluated. As ROP develops 1 month after birth, first profiles without (non-ROP), with (ROP group), those Type 1, 2, Stage 1+2 compared. Besides known statistical methods like Student's t-test, logistic regression classification & tree (C&RT) analysis also done...
Hypoxic ischemic encephalopathy (HIE) is a significant cause of mortality and short- long-term morbidities. Therapeutic hypothermia (TH) has been shown to be the standard care for HIE infants ≥36 weeks gestational age (GA), as it demonstrated reduce rates mortality, adverse neurodevelopmental outcomes. This study aims determine incidence in our country, assess TH management with HIE, present short-term outcomes these infants.The Turkish Ischemic Encephalopathy Online Registry database was...
Abstract Aim To assess the lung functions with impulse oscillometry (IOS) and spirometry in children type 1 diabetes mellitus (T1DM). Methods Fifty‐one T1DM, sex‐ age‐matched 53 healthy control (HC) subjects were included this study. Demographic, clinical, laboratory characteristics of recorded their pulmonary analyzed by IOS spirometry. Results In IOS, zR5, zR10, zR20 levels higher T1DM compared HCs ( P = .019, .017, .002, respectively). spirometry, zFEF75 zFEF25‐75 lower .025, .001, zR5‐20...
Akyüz-Ünsal Aİ, Key Ö, Güler D, Bekmez S, Sagus M, Akcan AB, Kurt-Omurlu İ, Anık A, Oruç-Dündar Türkmen M. Retinopathy of prematurity risk factors: Does human milk prevent retinopathy prematurity? Turk J Pediatr 2019; 61: 13-19. The aim this study was to investigate the factors for Prematurity (ROP) development and potential effect breast among these factors. For purpose, infants admitted a tertiary referral clinic ROP screening treatment between April 2013 May 2015, were included in...
Abstract Background Few data are available concerning normative lung function parameters measured in unsedated neonates. Aim To evaluate changes Methods In this prospective cohort study, tidal breath were using the MasterScreen PAED system and standardized protocols. Measurements performed on 60 (30 male) term, healthy, neonates postnatal 2nd 30th days. Results Expiratory time (TE; p < .001; Cohen's d = 0.561), exhaled volume to peak expiratory flow (VPTEF; 0.789), minute ventilation (...
To explore the iodine status of lactating mother-newborn pairs, and whether neonatal serum thyroid-stimulating hormone (TSH) can be used for estimation population.A total 334 mothers their healthy neonates were included. Urine, serum, breast milk samples obtained at 4th 6th days delivery. Urinary concentration (UIC) was measured in urine neonates, as well (BMIC) thyroid levels from taken between after birth.Median age 27 years (23-30). The median UIC newborns 125 μg/L 142 μg/L, respectively....
The lung functions of children with obese asthma seem to be distinct from those or lean asthmatics.To measure baseline function, exercise-induced bronchoconstriction (EIB), and bronchial hyperreactivity (BHR) in school-age asthmatics (OA group) compare the data (O group), (A healthy controls (H group).One hundred seventy were enrolled this prospective cross-sectional study. Baseline fractionated exhaled nitric oxide (FeNO), baseline, post-exercise (post-E), post-bronchodilation (post-BD)...
Objective: To investigate early outcome of non-traumatic coma (NTC) in pediatric critical care relation to prognostic role clinical, electroencephalographic and neuro-radiological factors. Methods: A total 77 children (mean(SD) age: 70.5±68.7 months, 55.8% were boys) with acute encephalopathy NTC included this retrospective cross-sectional study. Data on patient demographics (age, gender, etiology NTC) four factors [Glasgow scores (GCS), pupillary light reflex (PLR), EEG cranial MRI...
Objective: We aimed to investigate lung functions using tidal breath analysis (TBA) in high-risk infants with recurrent wheezing. Methods: Lung measured TBA physician-diagnosed wheezing (≥3 episodes) who applied our institution between 2018-2020, were retrospectively analyzed. Infants assigned two groups: (n=30) and wheezy without high risk of atopy (n=33). Results: High-risk had lower mean values tPTEF, tPTEF: tE, VPTEF, VPTEF: VE than that atopy. There was no significant difference groups...
Aim: This study aims to assess white blood cell count, platelet and indices as a metabolic indicator in overweight, obese morbidly children. Materials Methods:One-hundred thirty 341 obese, 188 children 110 controls were enrolled the study.Anthropometric measurements, pubertal status, complete count parameters [white cells (WBC), platelet, mean volume (MPV), plateletcrit (PCT), distribution width (PDW)], WBC differential (neutrophils, lymphocytes, monocytes), neutrophil/ lymphocyte ratio...
Objective The objective of this study was to evaluate the efficacy and safety isotonic hypotonic intravenous fluids in maintenance fluid therapy for term infants. Methods This a multi-centre, prospective, observational conducted 21 participating centres from December 30, 2020, June 2023. included newborns requiring parenteral (NCT04781361). treatment divided into two groups based on concentration sodium fluid, designated as (NaCl &lt;130 mmol/L) = 130–154 mmol/L). primary outcomes were...
The study aims to determine the normal values of thyroid volume and tracheal index in healthy term newborns born an iodine-sufficient population. Additionally, we investigated usability a handheld device for assessing index.
Objective: To evaluate the thiol/disulphide homeostasis and level of vascular endothelial growth factor (VEGF) in saliva children with type 1 diabetes mellitus gingivitis. Methodology: Forty [DM] 40 systemically healthy [H]) were recruited for study. Based on children’ periodontal systemic health status, they divided into four subgroups: 1) periodontally (Hh), 2) gingivitis (Hg), 3) diabetic (DM+h), 4) (DM+g). Periodontal clinical parameters recorded. A new automated technique was used to...
Many factors are affecting intrauterine growth. The role of Wingless-type (Wnt) inducible signaling pathway protein-1 (WISP1), a novel adipokine and placental proteoglycans in growth, is not known. We aimed to measure umbilical cord blood levels glucose, insulin, leptin, WISP1, [glypican-1 (GPC1), glypican-3 (GPC3), syndecan-1 (SDC1)] which thought have an important fetal growth investigate their relation with birth weight.Full-term neonates were included this prospective, cross-sectional...
In this study, the effect of applying wharton jelly mesenchymal stromal cells (WJ-MSC) isolated from human umbilical cord tissue on neonatal mouse model caused experimental asphyxia in mice was investigated. WJ-MSC surface markers (CD44, CD90, CD105) were characterised by immunofluorescence staining, and pluripotency genes (Nanog, Oct-4, Sox-2) qPCR. Blood, prefrontal cortex, cerebellum, hippocampus, lung, heart, kidney, liver tissues analysed twenty days after subcutaneously administered...
Abstract Background Effective treatment and close monitoring of hypoglycemia in children with congenital hyperinsulinemic (CHH) is vital to prevent brain damage. The current use capillary sampling schedules does not provide a comprehensive assessment glycemic status fails detect asymptomatic episodes. Aim To investigate the efficacy accuracy real-time continuous glucose system (RT-CGMS) neonates CHH. Methods A sensor connected RT-CGMS was inserted into newborn patients maintained for at...
Objective: Maturity-Onset Diabetes of the Young (MODY) is most common type monogenic diabetes. Heterozygous inactivating variants in glucokinase (GCK) gene are related to MODY2 (GCK–MODY). In this study, we aimed investigate phenotype and genotype characteristics patients with GCK–MODY. Methods: Anthropometric clinical (age, gender, weight, height body mass index, complaints, family history), laboratory data (glucose, insulin, glycated hemoglobin, lipid levels) molecular analysis GCK were...
INTRODUCTION: The aim of this study was to determine, (i) the cause congenital hypothyroidism (permanent or transient), (ii) etiological persistent and (iii) investigate role clinical laboratory data in predicting transient hypothyroidism. METHODS: Patients with who were started L-thyroxine treatment discontinued at age 3 years included study. cases obtained retrospectively from hospital records. Serum thyroid hormones measured 4 weeks after discontinuation years. TSH> 10 mIU/mL accepted...
Aim: To evaluate cases referred from the congenital hypothyroidism (CH) new-born screening program.Materials and Methods: One hundred thirty-five which were between January 2017 July 2019 included in study.Results: Fourty eight of 135 (35.6%) diagnosed as CH.The mean onset treatment was 17.31±9.92days.Clinical findings suggesting detected 27 patients (56.2%) goiter 2 (4.1%).According to imaging findings, 16 (35.5%)patients dysgenesis, [1 (2.2%) agenesia, 3 (6.7%)as ectopia, 12 (26.6%)as...
Objective: Considerable research has been reported about the problems of preterm neonates admitted to neonatal intensive care unit (NICU); however, number studies examining term is limited.Thus, this study examined NICU. Materials and Methods:The demographic clinical characteristics mothers NICU between January 1, 2015, December 31, 2020, were retrospectively from medical records.Neonates with major congenital anomalies, diagnosed genetic syndromes, or referred another hospital for any...