Abstract Objectives To compare the efficacy of intra‐articular injection and radiofrequency ( RF ) neurotomy genicular nerves in patients with chronic knee osteoarthritis OA pain. Methods Seventy‐three were included study. Patients randomly assigned to Group IA (intra‐articular 2.5 mL bupivacaine, mg morphine 1 betamethasone, 6 fluid injection) or nerves). The outcome measures a pain scale (visual analog scale, VAS Western Ontario McMaster Universities WOMAC Index Osteoarthritis. Results No...

Pruritus affects the quality of life (QoL) in patients. However, little is known impacts itching on QoL literature.In this study, a questionnaire eliciting specific responses about pruritus was used to determine effect and its severity chronic pruritic patients.One hundred ten adult patients with were surveyed. Once itch had been self-reported by patients, together Skindex-29, they have given 18-item Pruritus-related Life Quality Index (PLQI) questionnaire, which generated new...

The present study evaluated the effects of curcumin on epithelial cell apoptosis, immunoreactivity phospho–c-Jun N-terminal kinase (JNK) and phospho-p38 mitogen-activated protein kinases (MAPKs) in inflamed colon mucosa, oxidative stress a rat model ulcerative colitis induced by acetic acid. Rats were randomly divided into three groups: control, acid, acid+curcumin. Curcumin (100 mg/kg per day, intragastrically) was administered 10 days before induction continued for two additional days....

The aim of this study is to compare galanin and IL-6 levels in pregnant women with gestational diabetes mellitus (GDM) normal glucose tolerance (NGT). Also association insulin resistance markers, was investigated.The registered 30 GDM NGT. Fasting venous blood samples were collected from all patients. Galanin measured by an enzyme-linked immunosorbent assay.Galanin found higher (p < 0.001). A significant positive correlation determined between concentrations (r = 0.240, p 0.065), 0.681,...

Objectives To predict the risk of retinopathy prematurity (ROP) development according to routine complete blood count (CBC) parameters. Materials and Methods The medical records CBC results 150 premature neonates were retrospectively evaluated. As ROP develops 1 month after birth, first profiles without (non-ROP), with (ROP group), those Type 1, 2, Stage 1+2 compared. Besides known statistical methods like Student's t-test, logistic regression classification & tree (C&RT) analysis also done...

Ankylosing spondylitis (AS) is a chronic, inflammatory rheumatic disease characterized by the inflammation of pelvis and spine that results in restriction mobility spine. Due to altered posture nocturnal pain, sleep disturbances are likely occur patients with AS.This cross-sectional study aimed at determining differences between AS healthy controls quality, as well assessing relationship quality activity.In order assess fifty-five (40 men, 15 women; mean age, 43 ± 1 yrs) who fulfilled...

Précis: Elevated corneal hysteresis (CH) and resistance factor (CRF) in obese overweight children imply weight’s effect on biomechanics. Increased Goldmann-correlated intraocular pressure (IOPg) indicates glaucoma risk, emphasizing screening for IOP retinal changes. Purpose: To evaluate the of obesity biomechanics, nerve fiber layer (RNFL), central macular thickness (CMT) children. Patients Methods: In this prospective, cross-sectional, comparative study, 146 eyes normal-weight, over-weight,...

Purpose: The aim of this study was to compare the VEGF, PIGF, and HIF-1α levels in placentas early- late-onset pre-eclamptic patients, which are thought be important pathophysiology pre-eclampsia.Material method: Pre-eclamptic early-onset (n = 22) 24) pregnant women a control group healthy were recruited for case–control study. A semi-quantitative immunohistochemical analysis PIGF performed cross-sections subjects, after results compared.Results: Levels VEGF patients found lower than (p <...

Objective: Thalassemias major are the most common autosomal recessive disorders; they characterized by anomalies in synthesis of beta chains hemoglobin and often associated with varying degrees craniofacial anomalies.The purpose this study was to evaluate dimensions b-thalassemia patients identify differences comparing them those a control group. Materials Methods:The comprised 43 thalassemia 26 age-and sexmatched healthy subjects.Anthropometric measurements were performed six different...

The aim of this study was to evaluate the expression levels cardiac-related circulating microRNAs (miRNAs) in ST-elevation myo- cardial infarction (STEMI) patients.This has a prospective experimental cohort design. A total 12 consecutive patients with acute chest pain within h admit- ted emergency department (STEMI group) and 13 adult normal coronary angiography during same period were enrolled (control study. Changes miR-122, miR-208, miR-375, miR-22, miR-133b, miR-92b, miR-21, miR-133a,...

The aim of this study was to investigate whether thiamine pyrophosphate (TPP) has biochemical and histological preventive effects on oxidative liver damage induced by paracetamol (APAP). Rats were divided into the following groups: healthy control (HG), APAP (AG, 1500 mg/kg, orally), (TPPG, 100 intraperitoneally), APAP+NAC (ANAC, APAP+TPP (ATPG) APAP+NAC+TPP (ANTG). Oxidant, antioxidant parameters, function tests assessment performed between groups. Malondialdehyde levels in AG, HG, TPPG,...

Objective: Visfatin is one of the most recent proteins shown to be highly expressed in adipose tissue. The purpose this study was determine visfatin levels patients with endometrial cancer (EC).Methods: A total 90 (46 EC and 44 healthy controls) were included study. Fasting venous blood samples collected from all patients. Serum measured by an enzyme-linked immunosorbent assay (ELISA). correlation between serum clinicopathologic variables determined.Results: found higher (p < 0.001)....