A5058226199- Effects of Radiation Exposure
- Curcumin's Biomedical Applications
- Reproductive Biology and Fertility
- Sperm and Testicular Function
- Ultrasound and Hyperthermia Applications
- Veterinary Pharmacology and Anesthesia
- Oral microbiology and periodontitis research
- Pancreatic function and diabetes
- Natural Antidiabetic Agents Studies
- Biochemical effects in animals
- Anesthesia and Pain Management
- Anesthesia and Sedative Agents
- Testicular diseases and treatments
- Fatty Acid Research and Health
- Ovarian function and disorders
- Liver Disease Diagnosis and Treatment
- Urological Disorders and Treatments
- Oral Health Pathology and Treatment
- Pharmacological Effects of Medicinal Plants
- Helicobacter pylori-related gastroenterology studies
- Diabetes and associated disorders
- Metabolism and Genetic Disorders
- Genomics, phytochemicals, and oxidative stress
- Reproductive System and Pregnancy
- Nigella sativa pharmacological applications
Bülent Ecevit University
2015-2025
Süleyman Demirel University
2019
Trakya University
2000-2012
The present study evaluated the effects of curcumin on epithelial cell apoptosis, immunoreactivity phospho–c-Jun N-terminal kinase (JNK) and phospho-p38 mitogen-activated protein kinases (MAPKs) in inflamed colon mucosa, oxidative stress a rat model ulcerative colitis induced by acetic acid. Rats were randomly divided into three groups: control, acid, acid+curcumin. Curcumin (100 mg/kg per day, intragastrically) was administered 10 days before induction continued for two additional days....
Aim: Capsaicin is a compound that possesses antioxidant and anti-inflammatory properties, it found in almost all bitter fruits. The objective of our study was to investigate the protective effect capsaicin an ethanolic ulcer model. Materials Methods: male Wistar albino rats were divided into four groups, comprising control group three experimental groups (n=8). (C) administered single dose distilled water subcutaneously. (CAP) 1 mg/kg CAP via gavage. 1ml absolute alcohol gavage, 30 minutes...
The major objective of this study was to test curcumin as a potential radioprotectant for the ileum goblet cells rat. Wistar albino rats were used in study. Group A control group and B single dose radiation group. C two (4 days interval). groups D E given daily 100 mg/kg 14 18 days, respectively. During administration period, exposed abdominal area gamma (gamma)-ray 5 Gy on 10th day same 14th day. Irradiation treatment decapitated 4th after exposure or two-dose irradiation tissues removed...
Objective: The aim of the study was to determine protective effect curcumin against ionizing radiation-induced cataract in lens rats.Material and Methods: Rats were divided into six groups.Group 1: Control, Group 2: Dimethyl sulfoxide (DMSO), 3: DMSO+curcumin, 4: Irradiation, 5: Irradiation+DMSO, 6: Irradiation+DMSO+curcumin. A 15 Gy total dose given 4, 5, 6 groups for radiation damage.Curcumin (100 mg/kg) dissolved DMSO by intragastric intubation 28 days.At end experiment, lenses graded...
Background and Objective Periodontitis, a chronic inflammatory disease caused by oral bacterial infection, is considered to be risk factor for systemic diseases including diabetes mellitus, pneumonia, hyperlipidemia atherosclerosis. The aim of this study was evaluate the effectiveness melatonin against periodontal inflammation‐induced multiple organ injury in rats. Material Methods Eighteen female Wistar albino rats were randomly divided into three groups six each: control;...
Context Carbon tetrachloride (CCl4) is a chemical that still widely used in industry and has been shown to cause structural defects rat testicles through oxidative stress. Aims In our study, the effect of curcumin on CCl4-mediated testicular damage was investigated. Methods Twenty-four adult Wistar albino male rats weighing 300–350 g were divided into four groups: control group (olive oil applied by gavage every consecutive day for 3 weeks); CCl4 + groups (200 mg/kg dissolved olive given...
Aim: The protective effect of vitamin E (vit E) on cadmium (Cd) induced oxidative stress was studied in the blood rats. Methods: rats were randomly divided to three experimental groups: Control, Cd treated and + vit treated, each containing 10 animals. groups injected subcutaneously daily with CdCl2 dissolved isotonic NaCl amount 2 mL/kg for 20 days, resulting a dosage 0.49 mg Cd/kg/d. In addition, group received intramuscular injection 150 mg/kg until end study. Results: treatment increased...
In this study, we tested the effects of L-carnitine (LC) on radiation-induced ileal mucosal damage.Thirty Wistar albino rats were divided into five groups. The control group received physiological saline intraperitoneally (i.p.). Radiation-1 and radiation-2 groups whole-body X-irradiation 8.3 Gy as a single dose. These sacrificed at 6th hour 4th day after irradiation, respectively. + LC same dose irradiation plus daily 200 mg/kg LC. was applied one before for four days irradiation.The levels...
This study aimed to explore whether PARP-1 regulatory pathway mediated X irradiation induced cell cycle arrest and apoptosis or not. In this regard, colonic mucosal injury caused by whole-body X-irradiation through PARP-1, caspase 3 p53 were evaluated in experimental rat models. Eighteen Wistar albino rats divided into three groups. Two radiation groups received 8.3 Gy dose of as a single the control group physiological saline intraperitoneally. Radiation sacrificed after 6 h 4 days...
Abstract This study evaluated the possible effects of flaxseed oil on renal damage associated with hyperlipidaemic rats. Wistar albino male rats were divided into three groups. Group I was fed a pellet chow. II high cholesterol diet (HCD) consisting 5% and 0.35% cholic acid added to III same HCD, but orally treated dose 15 mg/kg body wt/day oil. Flaxseed treatment started 1 week before continued throughout 22 weeks HCD. At end experiment, tissue blood samples collected. The biochemical...
Purpose: Angiotensin converting enzyme inhibitors (ACEI) and type I angiotensin receptor blockers (ARB) have been shown to exert significant effects on bone tissue via a local renin-angiotensin-aldosterone system (RAS). The aim of our study was delineate their influences fracture healing process. Methods: Sixty adult male Wistar Albino rats were divided into three groups. After undergoing surgical femoral fixation, the ACEI group received 10 mg/kg Enalapril, ARB Losartan Control did not...
Structured Abstract Objects To investigate the effects of curcumin (CUR) and melatonin (MEL) on new bone formation following rapid maxillary expansion (RME) in rats. Setting Sample Population For this study, 24 12‐week‐old adult male Wistar albino rats from Animal Laboratory at Adnan Menderes University, Faculty Medicine, were used. Materials Methods The randomly divided into 3 groups (n = 8 each): only (OE), plus MEL CUR (CUR). given to during study period. After sacrifice animals,...