M.C. Uzal

ORCID: 0000-0001-6315-3483
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Research Areas
  • Breast Cancer Treatment Studies
  • HER2/EGFR in Cancer Research
  • Metabolism and Genetic Disorders
  • Estrogen and related hormone effects
  • Effects of Radiation Exposure
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Glioma Diagnosis and Treatment
  • Advanced Breast Cancer Therapies
  • Prostate Cancer Treatment and Research
  • Radiation Effects and Dosimetry
  • Lanthanide and Transition Metal Complexes
  • Lung Cancer Treatments and Mutations
  • Cancer Diagnosis and Treatment
  • Head and Neck Cancer Studies
  • Multiple and Secondary Primary Cancers
  • Head and Neck Surgical Oncology
  • Brain Metastases and Treatment
  • Bone health and osteoporosis research
  • Renal cell carcinoma treatment
  • Biochemical effects in animals
  • Birth, Development, and Health
  • Pharmacological Effects of Medicinal Plants
  • Cancer-related Molecular Pathways
  • Free Radicals and Antioxidants
  • Curcumin's Biomedical Applications

Trakya University
2001-2022

Istanbul Arel University
2022

Scientific and Technological Research Council of Turkey
2011

The major objective of this study was to test curcumin as a potential radioprotectant for the ileum goblet cells rat. Wistar albino rats were used in study. Group A control group and B single dose radiation group. C two (4 days interval). groups D E given daily 100 mg/kg 14 18 days, respectively. During administration period, exposed abdominal area gamma (gamma)-ray 5 Gy on 10th day same 14th day. Irradiation treatment decapitated 4th after exposure or two-dose irradiation tissues removed...

10.1007/s00204-008-0352-4 article EN cc-by-nc Archives of Toxicology 2008-08-26

Many studies report the triple negative breast cancer (TNBC) as worst subgroup, such patients do not benefit from anti-hormonal therapy and human epidermal growth factor receptor 2 (HER2) antagonists. While HER2 overexpression was a poor prognostic in before trastuzumab (Herceptin) available, TNBC is often reported BC subgroup since targeted currently possible. Since patience-specific experiences current literature did always align, we aimed to determine with shortest survival our center.The...

10.2147/bctt.s380754 article EN cc-by-nc Breast Cancer Targets and Therapy 2022-09-01

To determine 2 different prognostic indexes (PI) for the differentiation of subgroups nonmetastatic breast cancer patients with Cox regression analysis and survival tree (ST) methods additional usage Kaplan-Meier estimates to investigate predictive power these methods. Materials methods: Prognostic factors data were collected 410 patients. The examines relationship distribution covariates. ST method is a tree-structured based on recursive partitioning algorithm. In this study, Harrell's...

10.3906/sag-0909-257 article EN TURKISH JOURNAL OF MEDICAL SCIENCES 2011-01-01

Objective: Ibuprofen and L-carnitine have been demonstrated to provide radioprotective activity the hamster against whole body sublethal irradiation.The purpose of this study is test those antioxidant drugs, each which has capacity inhibiting mucosal injury, as topical radioprotectants for intestine.Material Methods: The male hamsters were divided into following four groups (n=6): group 1: control group, received saline, 1 ml/100 g by gavage, placebo.Group 2: irradiated-control irradiation 8...

10.5174/tutfd.2009.02685.2 article EN Trakya Üniversitesi Tıp Fakültesi dergisi 2009-01-01

Abstract Background: Breast cancer (BC) remains the most common in women, and it is second leading cause of cancer-related death women. Because advances treatment, long life now possible even patients with metastatic BC, whereas certain groups survive for a very short time despite being diagnosed at an early stage. In many studies, triple negative BC subgroup stated to have worst prognosis, as such are deprived antihormonal therapy trastuzumab therapy. While HER2 overexpression was...

10.21203/rs.3.rs-1447957/v1 preprint EN cc-by Research Square (Research Square) 2022-03-18

10.5222/otd.2016.1047 article EN The Medical Journal of Okmeydani Training and Research Hospital 2016-01-01

10.5222/otd.2017.1103 article EN The Medical Journal of Okmeydani Training and Research Hospital 2017-01-01
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