A5081664955- Lung Cancer Treatments and Mutations
- Cervical Cancer and HPV Research
- Nutrition, Genetics, and Disease
- Economic and Financial Impacts of Cancer
- BRCA gene mutations in cancer
- Spectroscopy and Chemometric Analyses
- Spectroscopy Techniques in Biomedical and Chemical Research
- Peptidase Inhibition and Analysis
- Cancer Genomics and Diagnostics
- COVID-19 and healthcare impacts
- Cancer Research and Treatments
- Infrared Thermography in Medicine
- Colorectal Cancer Treatments and Studies
- Cancer Treatment and Pharmacology
- Metabolomics and Mass Spectrometry Studies
- Testicular diseases and treatments
- Healthcare cost, quality, practices
- Hematopoietic Stem Cell Transplantation
- Lymphoma Diagnosis and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Health and Medical Research Impacts
- Sarcoma Diagnosis and Treatment
- Healthcare Quality and Management
- Neutropenia and Cancer Infections
- Photoacoustic and Ultrasonic Imaging
Tuxtla Gutierrez Institute of Technology
2022-2023
Universidad de Ciencias y Artes de Chiapas
2021-2022
Facultad Latinoamericana de Ciencias Sociales
2021
Center for Research and Advanced Studies of the National Polytechnic Institute
2006
Instituto Jalisciense de Cancerología
2005
University of Washington
2001-2003
Fred Hutch Cancer Center
1999-2001
Mexican Social Security Institute
2000
Cancer Consortium
2000
University of Puget Sound
2000
Randomized Controlled Trials (RCTs) in oncology are the backbone of advancing clinical practice oncology. Their significance is particularly pronounced high-impact and influential journals such as NEJM, The Lancet, Lancet Oncol, JAMA, JAMA JCO. However, previous works have highlighted that RCTs often fail to provide complete reporting survival endpoints, which can jeopardize oncologist's interpretation study findings. This a narrative review we some basic concepts statistics apply these...
Since December 2019, the world has been mired in an infectious pandemic that displaced other health priorities for 21st century populations. Concerned about this situation, Latin American experts on cancer decided to evaluate impact of control region. The analysis was based information obtained from public sources and scientific publications included characteristics care prior pandemic, COVID-19 measures implemented by governments region, regional together with costs possible expense. We...
In this study we identify and classify high low levels of glycated hemoglobin (HbA1c) in healthy volunteers (HV) diabetic patients (DP). Overall, 86 subjects were evaluated. The Raman spectrum was measured three anatomical regions the body: index fingertip, right ear lobe, forehead. measurements performed to compare difference between HV DP (22 well controlled (WCDP) (HbA1c <6.5%), 49 not (NCDP) ≥6.5%)). Multivariable methods such as principal components analysis (PCA) combined with support...
Undiagnosed type 2 diabetes (T2D) remains a major public health concern. The global estimation of undiagnosed is about 46%, being this situation more critical in developing countries. Therefore, we proposed non-invasive method to quantify glycated hemoglobin (HbA1c) and glucose vivo. We developed technique based on Raman spectroscopy, RReliefF as feature selection method, regression feed-forward artificial neural networks (FFNN). spectra were obtained from the forearm, wrist, index finger 46...
Describe the prevalence of breast cancer (BC)- associated germline pathogenic variants (PVs) among Mexican patients with triple-negative BC (TNBC).The spectrum PVs identified TNBC who were enrolled in a prospective registry and underwent genetic testing was analyzed.Of 387 invasive median age at diagnosis 39 years (range 21-72), 113 (29%) carriers BC-susceptibility genes: BRCA1 (79%), BRCA2 (15%), other (6%: ATM, BRIP1, PALB2, PTEN, RAD51C, TP53). PV younger (37 vs. 40 years, p=0.004) than...
Abstract Background: The prevalence of germline pathogenic variants in Mexican women with breast cancer who met the reference criteria for genetic risk assessment (GCRA) has been previously reported as close to 20%. However, information regarding spectrum gPVs genes other than BRCA this population is limited. Methods: This prospective study included were diagnosed BC and international GCRA. Participants enrolled Clinical Cancer Genomics Community Research Network (CCGCRN) registry at two...
1521 Background: Breast cancer is the second cause of death from among Mexican women but incidence continues to rise mainly in rural communities. However, older than 50 years, only 7% them report having had a mammogram because insufficient number mammography equipment and trained health care professionals. Mammography has limitation sensitivity specificity greater 70 % 80 %, respectively. thermography noncontact, noninvasive technique easy use outside hospitals. We propose evaluate...
Choosing Wisely is an initiative by the American Board of Internal Medicine (ABIM) and ABIM Foundation to deter unnecessary medical treatments procedures. Faced with burden modern technologies treatments, it crucial identify practices lacking value in daily care. The Latin Caribbean Society (SLACOM), comprising cancer control experts, deems vital tailor this for enhancing care region. Through a modified DELPHI methodology involving two rounds electronic questionnaires hybrid meeting discuss...
This study aimed to identify, evaluate, and rank suitable safety innovations developed during the COVID-19 pandemic in Latin American Caribbean (LAC) radiation oncology centers.
Sotorasib, the first RAS inhibitor FDA-approved drug for advanced, KRASG12C-mutated non-small cell lung cancer (NSCLC), was approved in May 2021 under FDA-Accelerated Approval program. This commentary critically reviews results on progression-free survival (PFS) and overall (OS) of CodeBreaK 200 trial, a randomized, open-label, phase 3 trial published The Lancet 2023. study reported increased PFS with sotorasib based reduced hazard ratio (HR). Despite FDA's rejection regular approval October...
Sotorasib, the first RAS inhibitor FDA-approved drug for advanced, KRASG12C-mutated non-small cell lung cancer (NSCLC), was approved in May 2021 under FDA-Accelerated Approval program. This commentary critically reviews results on progression-free survival (PFS) and overall (OS) of CodeBreaK 200 trial, a randomized, open-label, phase 3 trial published The Lancet 2023. study reported increased PFS with sotorasib based reduced hazard ratio (HR). Despite FDA's rejection regular approval October...
Breast cancer is a major public health problem worldwide. Important advances have improved survival, but early detection remains the main clinical challenge in reducing mortality. Currently, mammography ‘gold standard’ tool for breast screening. However, search an method subject of extensive research. Although infrared imaging or thermography has been evaluated since late 1950s, negative results reported 1979 by Cancer Detection and Demonstration Project decreased interest this modality....
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1533 Background: Rural and indigenous women are generally considered to be at lower risk of breast cancer than living in urban environments. However, a rising incidence rates among those has been reported. Moreover, up 90% diagnosed as having advanced disease. With the aim improve preventive programs that population, this study evaluated socio-demographic factors associated with early detection women's knowledge about malignancy. Methods: Between March 2008 November 2008, attending screening...
Abstract Background: Patients at increased risk of breast (BC) and/or ovarian (OC) cancer can opt for risk-reducing surgeries (RRS). However, there are disparities in access to genomic assessment (GCRA) and prevention interventions related geography, socioeconomic status, limited public health support. We studied factors that affect the uptake mastectomy (RRM) salpingo-oophorectomy (RRSO) Hispanic patients Latin America (LatAm) United States (US). Methods: women enrolled Clinical Cancer...