A5048566105- Neonatal Respiratory Health Research
- Congenital Diaphragmatic Hernia Studies
- Connective tissue disorders research
- Urological Disorders and Treatments
- Infant Development and Preterm Care
- Infant Nutrition and Health
- Neonatal Health and Biochemistry
- Sepsis Diagnosis and Treatment
- Retinopathy of Prematurity Studies
- Hernia repair and management
- Congenital Heart Disease Studies
- Vascular Malformations Diagnosis and Treatment
- Intracranial Aneurysms: Treatment and Complications
- Lysosomal Storage Disorders Research
- Pediatric Urology and Nephrology Studies
- Congenital gastrointestinal and neural anomalies
- Pregnancy and preeclampsia studies
- Tracheal and airway disorders
- Neonatal and Maternal Infections
- Craniofacial Disorders and Treatments
- Neuroscience of respiration and sleep
- Breastfeeding Practices and Influences
- Vascular anomalies and interventions
- Inflammatory Myopathies and Dermatomyositis
- Cardiac Arrhythmias and Treatments
Pamukkale University
2024
Sağlık Bilimleri Üniversitesi
2019-2023
University of Health Science
2023
Bursa Yuksek Ihtisas Egitim Ve Arastirma Hastanesi
2015-2019
Zekai Tahir Burak Kadın Sağlığı Eğitim ve Araştırma Hastanesi
2010-2014
Education Training And Research
2014
Fairfax Neonatal Associates
2012
Zübeyde Hanim Maternity Hospital
2012
<b>Objective</b> To investigate the effectivity of pentoxifylline (PTX) and immunoglobulin M (IgM)-enriched intravenous (IVIG) therapy in treatment neonatal sepsis (NS), alone or combination. <b>Study design</b> This was a prospective, double-blind, controlled study. Newborns with suspicion were enrolled The patients separated into four groups according to protocol: Group 1 = placebo, 2 pentoxifylline, 3 IgM-enriched IVIG, 4 + IVIG. Blood samples taken for C-reactive protein, interleukin-6,...
Hypoxic ischemic encephalopathy (HIE) is a significant cause of mortality and short- long-term morbidities. Therapeutic hypothermia (TH) has been shown to be the standard care for HIE infants ≥36 weeks gestational age (GA), as it demonstrated reduce rates mortality, adverse neurodevelopmental outcomes. This study aims determine incidence in our country, assess TH management with HIE, present short-term outcomes these infants.The Turkish Ischemic Encephalopathy Online Registry database was...
To determine total antioxidant capacity and oxidation status in fresh freeze stored (at -80°C) breast milk during the stages of lactation.Samples colostrum, transitional mature were collected from 44 healthy women at 3, 8 30 days after birth. The volume (6 ml) was divided two aliquot parts: 3 ml for analysis which done immediately extraction storage under freezing conditions -80°C months. oxidative stress assessed via determination status.Antioxidant decreased (p = 0.0001, p 0.028,...
We aimed to evaluate normal and pre-eclamptic placental vasculature by using CD31 Factor VIII. evaluated placentas of 37 women immunohistochemical staining with VIII antibodies. Individual microvessels in the tissues were counted at × 100 400 magnification. Microvessel counts lower patients compared healthy controls after (26.5 ± 5.7 vs 103.9 8.2, p < 0.001) (24.8 6.7 98.7 10.3, 0.001). Balance between proangiogenic antiangiogenic factors seems be shifted favour anti-angiogenic pre-eclampsia.
Objective: In this study, pulse oximetry screening results in the early diagnosis of critical congenital heart diseases (CCHD) will be evaluated.Methods: Eight-thousand two-hundred and eight 10 200 newborns born between January 2014 December were screened using for CCHD. Screening test was considered to positive whose saturation after 24 h from birth with ≤95% and/or who had a difference ≥3% lower right upper extremity.Results: Incidence CCHD 1 per 1000 live births. Coarctation aorta most...
Objective To investigate the early neonatal outcomes of very-low-birth-weight (VLBW) infants discharged home from intensive care units (NICUs) in Turkey. Material and methods A prospective cohort study was performed between April 1, 2016 30, 2017. The included VLBW admitted to level III NICUs. Perinatal data all born with a birth weight ≤1500 g were collected for who survived. Results Data 69 NICUs obtained. mean gestational age 1137±245 29±2.4 weeks, respectively. During period, 78%...
It is essential to establish optimum parameters for maintaining the quality of stored milk until moment consumption with minimal deterioration its properties. The aim study was evaluate total antioxidant capacity (TAC) and oxidation status (TOS) fresh freeze-stored samples (at -80°C) preterm human (HM).Samples colostrum were collected from 98 healthy women within first 4 days after delivery. volume (6 ml) divided in two aliquot parts: 3 ml analysis which done immediately extraction storage...
Perinatal-lethal Gaucher disease is very rare and considered a variant of type 2 that occurs in the neonatal period. The most distinct features perinatal-lethal are non-immune hydrops fetalis, utero fetal demise distress. In some cases without hydrops, neurological signs occur first week life lead to death within 3 months. Less common hepatosplenomegaly, ichthyosis, arthrogryposis facial dysmorphy. We describe preterm neonate with homozygous for R463H mutation GBA gene who showed severe...
Introduction: Glutathione synthetase (GSS) deficiency is an autosomal recessive disorder (frequency < 1/1,000,000) with different varyingly severe clinical manifestations that include metabolic acidosis, hemolytic anemia, hyperbilirubinemia, neurological disorders and sepsis. Case report: This infant was small for gestational age, had bilateral subependymal pseudocysts increased echogenicity of the basal ganglia. GSS confirmed by genetic analysis. The patient also unilateral right femur...
Omphalocele, exstrophy of cloaca, imperforate anus and spinal defect (OEIS Complex) is an extremely rare combination serious defects, which was firstlydescribed by Carey colleagues. Surgical repair cloacal exctrophy in patientswith OEIS complex can be performed at one stage, but it also performedsafely as staged to minimize the potential complications. In this case report, weaimed present our early approach complex.
Pulmonary sequestration is acystic or solid congenital lung malformation comprised of non functional tissue that does not communicate with the normal tracheobronchial tree and has a systemic arterial blood supply. There are two forms sequestration: intralobar extralobar. Its treatment surgical resection. Here we presented case premature neonate extralobar pulmonary who had respiratory failure recurrent hemorrhage. Following surgery, patient showed significant clinical improvement.El...
Objective: While routine administration of rhesus (Rh) immunoglobulin has significantly reduced the incidence Rh alloimmunization, maternal alloimmunization to other red cell antigens remains a contributor perinatal morbidity and mortality.Although Kell antigen is seen on cells only 9% general population, attention antibodies continues increase.Case Report: A case fetal hydrops was sonographically detected at 30 weeks gestation.Antenatal tests evaluate fetus's condition clearly showed that...
The presence of a palpable mass is an independent predictor microinvasion in Ductal Carcinoma situ the Breast Abstract Introduction cancer most common among women worldwide. (DCIS) one types these cancers. Factors associated with still need to be investigated. Materials and methods In this retrospective study, we analyzed data from 70 female patients diagnosed DCIS managed at tertiary center between 2011 2024. Demographic parameters, clinicopathological characteristics, immunohistochemical...
Purpose: This study was performed to determine whether one drop of topical administration Coqun® (Coenzyme Q10 and Vitamin E)-a potent antioxidant-twice a day has any effect on the thiol-disulphide homeostasis-a novel oxidative stress marker in Retinopathy Of Prematurity (ROP) disease course. Methods: prospective observational comprising 28 infants with ROP at stage 2 higher who followed up paediatric intensive care unit. Ferric reducing power plasma (FRAP), albumin, ischemia-modified...
Achondrogenesis is a group of rare and fatal disorders occurring in approximately one every 40,000-60,000 newborns. classified three groups, as type 1A (Houston-Harris or AC-G1A), 1B (Parenti-Fraccaro ACG1B) 2 (Langer-Saldino ACG2), depending on clinical radiological findings. Type lethal skeletal dysplasia that typically characterized by short arms legs, small chest with ribs, lung hypoplasia, prominent forehead, chin, an enlarged abdomen may accompanied polydramnios hydrops. This study...
Optimal care in the delivery room is important to decrease neonatal morbidity and mortality. We aimed evaluate resuscitation practices Turkish centers.A cross-sectional survey consisted of a 91-item questionnaire focused on was sent 50 centers. Hospitals with <2500 those ≥2500 births/year were compared.In 2018, approximately 240 000 births occurred at participating hospitals median 2630 births/year. Participating able provide nasal continuous-positiveairway-pressure/high-flow cannula,...
Abstract Introduction : Neonatal polycythemia may result in increased cytokine production. We aimed to investigate whether and partial exchange transfusion (PET) affect interleukin‐6 (IL‐6) response pattern early neonatal period. Methods Ninety‐four newborns, 57 with (Group 1) 37 as control group 2) were enrolled the study. PET was performed at 4–6 hr following birth first group. Blood levels of IL‐6 measured 2–4 birth; measurements repeated 6 24 after newborns similar hours Group 2. In 1,...
In children, any ureter greater than 7 mm in diameter is considered a megaureter based on measurements fetuses 30 weeks gestation and children <12 years. Primary (POM) result of functional or anatomical abnormality involving the uretero-vesical junction. Although endoscopic surgical techniques to manage POM are successful, we thought that early intervention may cause undesirable results.
ÖZGİRİŞ: Prematürelerde postnatal CMV (sitomegalovirüs) enfeksiyonu en sık enfekte anne sütü alımı ile kazanılmaktadır.Diğer bulaş yolları perinatal dönemde genital sekresyonlar ve kan transfüzyonudur.Tanı 3. haftadan sonra idrar, sekresyonlarda PCR ya da kültür virüsün izole edilmesine dayanmaktadır.Term olgularda enfeksiyon çoğunlukla asemptomatiktir
Prune belly syndrome is a rare congenital disorder defined by characteristic clinical triad: Abdominal muscle deficiency, severe urinary tract abnormalities,and bilateral cryptorchidism. We describe preterm neonate of Bellysyndrome who had abdominal multicystic dysplastic kidney,urethral hypoplasia and pulmonary hypoplasia. presented this case withthe data gathered from the literature.