A5041796033- Neonatal Respiratory Health Research
- Neonatal and Maternal Infections
- Infant Nutrition and Health
- Respiratory Support and Mechanisms
- Retinopathy of Prematurity Studies
- Pregnancy and preeclampsia studies
- Neonatal and fetal brain pathology
- Gestational Diabetes Research and Management
- Metabolism and Genetic Disorders
- Neuroscience of respiration and sleep
- Neonatal Health and Biochemistry
- Mitochondrial Function and Pathology
- Bacterial Infections and Vaccines
- Congenital Diaphragmatic Hernia Studies
- Streptococcal Infections and Treatments
- Infectious Encephalopathies and Encephalitis
- Sepsis Diagnosis and Treatment
- Immunodeficiency and Autoimmune Disorders
- Respiratory viral infections research
- Amino Acid Enzymes and Metabolism
- Pneumonia and Respiratory Infections
- Congenital Heart Disease Studies
- Tuberculosis Research and Epidemiology
- Rabies epidemiology and control
- Infant Development and Preterm Care
Bülent Ecevit University
2007-2024
University of Buckingham
2024
Zekai Tahir Burak Kadın Sağlığı Eğitim ve Araştırma Hastanesi
2009-2012
Ministry of Health
2011
Pediatrics and Genetics
2009
Boston Children's Hospital
2008
Dr Sami Ulus Çocuk Sağlığı ve Hastalıkları Eğitim ve Araştırma Hastanesi
2005-2006
<h3>Background</h3> Invasive fungal infections are a major cause of morbidity and mortality in preterm infants. The authors conducted the first prospective, randomised controlled trial nystatin compared with fluconazole for prevention colonisation invasive infection very low birth weight (VLBW) neonates. <h3>Methods</h3> During 12-month period, all VLBW neonates were assigned randomly to receive (1 ml suspension, 100 000 U/ml, every 8 h), (3 mg/kg body weight, third day) or placebo from...
Objective: To investigate the value of fecal calprotectin in diagnosis and predicting severity necrotizing enterocolitis (NEC) preterm infants. Methods: A prospective controlled study was conducted including infants with stage 2 to 3 NEC, birth weight gestational age-matched controls. Fecal samples were obtained both at time NEC 3–5 days later from patients, similar postnatal age Results: Twenty-five 25 controls enrolled. Median concentrations 1,282 365 µg/g controls, respectively. levels...
Sepsis is a leading cause of morbidity and mortality among newborns. C-reactive protein (CRP) procalcitonin (PCT) have some limitations in the diagnosis preterm neonatal sepsis. In this study, cut-offs PCT CRP, efficacy mean platelet volume (MPV) were investigated. We identified key demographic details compared laboratory values between infants with early onset late sepsis (EONS/LONS) retrospectively. Blood samples collected within first few hours clinical (CRP 1, MPV 1) repeated after 24 h...
We prospectively evaluated the differences in clinical responses and short-term outcomes preterm infants with respiratory distress syndrome (RDS) treated poractant alfa or beractant. Premature RDS were randomized to beractant treatment between July 2008 June 2009. Patients followed until 40 weeks of corrected gestational age death. The fraction inspired oxygen (F<sc>io</sc> <sub>2</sub>) after surfactant treatment, need for repeat doses, duration support hospitalization groups. Sixty-one...
Purpose: We aimed to determine applicable guidelines for screening of retinopathy prematurity (ROP), and evaluate the contribution risk factors severe ROP.Methods: A prospective cohort study neonates with a gestational age (GA) < 34 weeks or birth weight 2000g who were admitted Neonatal Intensive Care Unit (NICU) tertiary level hospital was conducted. The group classified into three groups according eye examination findings as no ROP, mild ROP ROP.Results: Of 700 screened, frequencies any...
A 14-year-old girl was referred to our hospital with lethargy and hypotension found have a serum magnesium level of 14.9 mg/dL after having received an hydroxide (Magnesie Calcinee) for 7 days because constipation. She lethargic, her blood pressure 70/40 mm Hg, electrocardiogram revealed prolonged corrected QT interval first-degree atrioventricular block. has no renal dysfunction. Emergency hemodialysis condition ameliorated, levels returned normal. The present case suggests that massive...
Oxidative damage is important in the pathogenesis of respiratory distress syndrome (RDS). However, data on effect surfactant therapy oxidative stress vivo are limited. We aimed to evaluate oxidant/antioxidant status preterm infants with RDS via measurement total antioxidant capacity (TAC) and oxidant (TOS), determine balance assess association between TAC, TOS clinical outcomes patients.Sixty-nine were included. Blood samples for determining TAC collected before 48 h after treatment. levels...
Abstract Aim Nijmegen breakage syndrome (NBS) is an autosomal recessive DNA repair disorder which characterized by immunodeficiency and increased risk of lymphoproliferative malignancy. Case We observed increase in the rate chromosomal rearrangements cultured cells following incidental radiograph for craniosynostosis a newborn who was followed up due to microcephaly. identified homozygous deletion c.657_661delACAAA/p.Lys219fs (rs587776650) NBN gene through whole exome sequencing. Conclusion...
Abstract Tricyclic antidepressant poisoning is one of the most common causes serious intoxication. Here, we report a 2‐year‐old girl with severe amitriptyline (70 mg/kg) She was in comatose, had generalized tonic clonic seizure, ventricular tachycardia, and wide QRS complexes. Although she did not respond to classical therapies, very good clinical response plasmapheresis obtained developed no complications. Thus, may be an effective treatment modality drugs, which bind plasma proteins high...
Objective To investigate the early neonatal outcomes of very-low-birth-weight (VLBW) infants discharged home from intensive care units (NICUs) in Turkey. Material and methods A prospective cohort study was performed between April 1, 2016 30, 2017. The included VLBW admitted to level III NICUs. Perinatal data all born with a birth weight ≤1500 g were collected for who survived. Results Data 69 NICUs obtained. mean gestational age 1137±245 29±2.4 weeks, respectively. During period, 78%...
Aims: There is growing body of evidence that oxidative stress plays an important role in the pathogenesis diabetes mellitus (DM) and development maternal fetal complications diabetic pregnancies. The aim present study was to investigate total antioxidant capacity (TAC), oxidant status (TOS), index (OSI) infants mothers (IDM) reveal influence hyperglycemia on these parameters.
Large for gestational age (LAG) neonates who had been exposed to an intrauterine environment of either diabetes or maternal obesity are at increased risk developing the metabolic syndrome. This can be explained by exposure high glucose and insulin levels in utero which alter fetal adaptation programming.The aim study was evaluate onset preclinical atherosclerosis utero.We measured umbilical artery wall thickness (ruWT) third trimester obstetric ultrasound intima-media (uIMT) pathologic...
Preterm neonates are susceptible to infection due a combination of sub-optimal immunity and increased exposure invasive organisms. Invasive fungal infections associated with significant morbidity mortality among preterm infants cared for in the neonatal intensive care unit (NICU). Mannose-binding lectin (MBL) is component innate immune system, which may be especially important setting. The objective this study was investigate presence any association between MBL gene polymorphism nosocomial...
Pediatric soft tissue infections (STIs) are frequently seen disorders that represent one of the most common indications for antimicrobial therapy. We conducted a retrospective analysis 242 patients who were hospitalized with STIs during period from January 2000 to 2004. The ages ranged 1 month 180 months (mean 44.33 ± 36.92 months). distributed as cellulitis in 96 (39.7%) patients, cervical lymphadenitis 62 (25.6%), abscess 49 (20.2%), subcutaneous 25 (10.3%), pyomyositis 6 (2.5%) and...