- Neonatal Respiratory Health Research
- Infant Nutrition and Health
- Infant Development and Preterm Care
- Neuroscience of respiration and sleep
- Neonatal and fetal brain pathology
- Congenital Diaphragmatic Hernia Studies
- Neonatal and Maternal Infections
- Neonatal Health and Biochemistry
- Birth, Development, and Health
- Pregnancy and preeclampsia studies
- Congenital Heart Disease Studies
- Respiratory Support and Mechanisms
- Cardiovascular Conditions and Treatments
- Sepsis Diagnosis and Treatment
- Preterm Birth and Chorioamnionitis
- Breastfeeding Practices and Influences
- Inflammatory Biomarkers in Disease Prognosis
- Clinical Nutrition and Gastroenterology
- Pediatric Hepatobiliary Diseases and Treatments
- Congenital Anomalies and Fetal Surgery
- Metabolism and Genetic Disorders
- Mechanical Circulatory Support Devices
- Retinopathy of Prematurity Studies
- Airway Management and Intubation Techniques
- Maternal and fetal healthcare
Sağlık Bilimleri Üniversitesi
2018-2025
University of Health Science
2023-2025
Çankaya University
2019-2025
Memorial Ankara Hospital
2020-2024
City Hospital
2021-2024
Ministry of Health
2011-2024
Ankara Bilkent City Hospital
2024
Ankara University
2023
Ministry of Health of the Russian Federation
2023
Bilkent University
2023
The primary aim of this randomized study was to describe the feasibility early administration surfactant via a thin catheter during spontaneous breathing (Take Care) and compare mechanical ventilation (MV) requirement with InSurE (Intubate, Surfactant, Extubate) procedure.Preterm infants, who were <32 weeks stabilized nasal continuous positive airway pressure (nCPAP) in delivery room, receive treatment either by Take Care or technique. Tracheal instillation 100 mg/kg poractant α 5-F under...
Compared with term infants, late preterm infants are immature physiologically and metabolically, have higher risks for medical complications such as respiratory distress, hypoglycemia, hyperbilirubinemia, sepsis, feeding difficulty poor neurodevelopmental outcomes. The incidence of birth is increasing. We evaluated the clinical demographic characteristics, short-term outcomes courses admitted to our neonatal intensive care unit (NICU). Data from NICU admissions 605 1477 in 1-year period...
<h3>Objective</h3> To compare the effectiveness of nasal continuous positive airway pressure (NCPAP) and intermittent positive-pressure ventilation (NIPPV) as initial respiratory support within minimally invasive surfactant therapy (MIST) approach in preterm infants with distress syndrome. <h3>Design</h3> Prospective, randomised controlled study. <h3>Setting</h3> Tertiary neonatal intensive care unit. <h3>Patients interventions</h3> This study enrolled 200 a gestational age 26–32 weeks who...
The aim of this study was to investigate the relationship between four circulating adipocytokines (apelin, vaspin, visfatin, adiponectin) and markers insulin sensitivity, in context polycystic ovary syndrome (PCOS) adolescents. 48, obese, adolescent girls (mean age: 15.6±3.4 years, mean body mass index standard deviation score (BMI-SDS): 2.31±0.1), 37 control subjects 16.2±3 BMI-SDS: 2.17±0.05) were enrolled study. diagnosis PCOS established according Rotterdam criteria. Hyperinsulinism...
Background The aim of this study was to investigate any changes in mean platelet volume (MPV) patients with neonatal sepsis ( NS ). Methods Subjects were stratified into two groups: proven (Group 1a) and clinical 1b). control group 2) consisted healthy newborns matched for gestational age birth weight. Results A total 100 (35 65 sepsis) 50 controls enrolled. comparison markers obtained at baseline revealed white blood cell count (WBC), C‐reactive protein CRP ), interleukin‐6 (IL‐6), MPV...
To determine the effect of delivery type on macronutrient content colostral milk.The study was conducted at Zekai Tahir Burak Maternity Teaching Hospital. Colostral milk samples from term lactating mothers who gave birth by vaginal or cesarean (CD) were obtained 2nd postpartum day. Milk protein, fat, carbohydrate (CHO) and energy levels measured using a mid-infrared human analyzer.A total 204 recruited to study; 111 route 93 CD. Protein statistically lower in after CD compared delivered...
Objective: To investigate the value of fecal calprotectin in diagnosis and predicting severity necrotizing enterocolitis (NEC) preterm infants. Methods: A prospective controlled study was conducted including infants with stage 2 to 3 NEC, birth weight gestational age-matched controls. Fecal samples were obtained both at time NEC 3–5 days later from patients, similar postnatal age Results: Twenty-five 25 controls enrolled. Median concentrations 1,282 365 µg/g controls, respectively. levels...
The early use of broad-spectrum antibiotics remains the cornerstone for treatment neonatal late onset sepsis (LOS). However, which should be used is still debatable, as relevant studies were conducted more than 20 years ago, recruited in single centres or countries, evaluated not clinical anymore and had variable inclusion/exclusion criteria outcome measures. Moreover, antibiotic-resistant bacteria have become a major problem many countries worldwide. We hypothesized that efficacy meropenem...
ABSTRACT Objective To evaluate the incidence of thin catheter surfactant administration (TCA) failure and compare short long‐term neonatal outcomes who failed TCA or did not. Design Single‐center retrospective cohort study. Infants between 25 30 weeks gestational age with respiratory distress syndrome receiving 200 mg/kg poractant alfa via were included. was defined as need for early mechanical ventilation (< 72 h). divided into two groups those Results The rate 24.6%. Initial oxygen...
Objectives: This study aims to identify risk factors and clinical markers for refractory patent ductus arteriosus the initial medical treatment determine appropriate strategies. The goal is define newborns who will respond prevent patients from adverse effects of or surgical arteriosus. Methods: Preterm infants with hemodynamically significant whose gestational age was under 30 weeks were retrospectively evaluated. Infants responded (paracetamol ibuprofen) compared those non-responders....
Abstract The aim of this study was to investigate the differences in mean platelet volume (MPV) between neonates with and without neonatal respiratory distress syndrome (RDS). Eighty‐three premature infants who were admitted intensive care unit included study. Forty‐four these diagnosed as having RDS other 39 non‐RDS patients. Infants born mothers pre‐eclampsia, or a drug history that had negative effects on count, perinatal hypoxia, sepsis necrotizing enterocolitis excluded. Blood...
Chorioamnionitis (CA) is an acute inflammation of the membranes and chorion placenta. The aim this study was to determine effect histological CA on short-term outcome preterm infants.The clinical characteristics outcomes infant including respiratory distress syndrome, duration mechanical ventilation, patent ductus arteriosus (PDA) requiring medical treatment or ligation, necrotizing enterocolitis, bronchopulmonary dysplasia, death intraventricular hemorrhage (IVH; grade III-IV) were...
Objective This study aims to determine the effects of paracetamol versus ibuprofen treatment given preterm infants for pharmacological closure patent ductus arteriosus (PDA) on neurodevelopmental outcomes at 18 24 months' corrected age. Method A follow-up was conducted evaluate (gestational age ≤ 30 weeks) enrolled in a randomized controlled trial comparing oral PDA. The developmental assessment done by using “Bayley Scales Infant Development, Second Edition” Results total 80 completed...
We retrospectively reviewed the medical records of all Syrian immigrants from TurkishSyrian border who delivered Zekai Tahir Burak Maternity and Teaching Hospital Neonatal Intensive Care Unit (NICU) in Ankara, Turkey. Between January 2013 December 2014 a total 36,346 women gave birth at this center. Of these, 457 were immigrants, comprising 1.2 % (457/36,346) deliveries. The number births among refugees Turkey appears to be increasing. Further research is needed understand relative morbidity...
The aim of the study was to evaluate neurodevelopment outcomes very low birth weight (VLBW) preterm infants supplemented with oral probiotics for prevention necrotizing enterocolitis (NEC).A prospective follow-up performed in a cohort VLBW enrolled single center randomized controlled clinical trial efficacy NEC. Cognitive and neuromotor developments were assessed by using Bayley scales infant development II. Sensory neurological performance evaluated standard techniques. primary outcome...
AbstractObjective: Platelet mass index (PMI) is related to the platelet functionality. The aim of this study was evaluate correlation between PMI and occurrence various inflammation-related morbidities prematurity, such as bronchopulmonary dysplasia (BPD), necrotizing enterocolitis (NEC), retinopathy prematurity (ROP), intraventricular hemorrhage (IVH) sepsis in very low-birth weight (VLBW) infants.Methods: This retrospective analysis VLBW infants admitted a level 3 neonatal intensive care...
Neonatal encephalopathy is a major cause of neonatal mortality and morbidity.Therapeutic hypothermia standard treatment for newborns at 35 weeks gestation or more with intrapartum hypoxia-related encephalopathy.Term late preterm infants moderate-to-severe show improved survival neurodevelopmental outcomes 18 months age after therapeutic hypothermia.Therapeutic can increase without increasing disability.Neonates severe remain risk death impairment.This guideline was prepared by the Turkish...
Abstract Functional gastrointestinal disorders (FGIDs) are characterized by a variety of symptoms that frequently age-dependent, chronic, or recurrent and not explained structural biochemical abnormalities. There studies in the literature reporting different results regarding relationship between prematurity FGIDs. The main objective this study was to compare frequency FGIDs preterm term infants. secondary evaluate whether there any association neonatal characteristics development A...