A5088320363- Neonatal Respiratory Health Research
- Infant Nutrition and Health
- Congenital Diaphragmatic Hernia Studies
- Infant Development and Preterm Care
- Respiratory Support and Mechanisms
- Neuroscience of respiration and sleep
- Pregnancy and preeclampsia studies
- Breastfeeding Practices and Influences
- Neonatal and fetal brain pathology
- Asthma and respiratory diseases
- Congenital Heart Disease Studies
- Pediatric Hepatobiliary Diseases and Treatments
- Clinical Nutrition and Gastroenterology
- Congenital Anomalies and Fetal Surgery
- Cardiovascular Conditions and Treatments
- Urological Disorders and Treatments
- Cardiac Arrhythmias and Treatments
- Birth, Development, and Health
- Child Nutrition and Feeding Issues
- Pediatric health and respiratory diseases
- Neonatal Health and Biochemistry
- Child Nutrition and Water Access
- Airway Management and Intubation Techniques
- Infant Health and Development
- Global Maternal and Child Health
Zekai Tahir Burak Kadın Sağlığı Eğitim ve Araştırma Hastanesi
2011-2025
Sağlık Bilimleri Üniversitesi
2018-2025
University of Health Science
2022-2025
Ministry of Health
2022-2024
Çankaya University
2020-2024
Memorial Ankara Hospital
2020-2023
Ankara Bilkent City Hospital
2022-2023
Ankara Mevki Asker Hastanesi
2020-2022
University of Health Sciences Antigua
2022
University of Health Sciences
2022
Background: There is ample evidence for the existence of a systemic oxidative stress in childhood asthma but relatively little information on oxidant airways. Objective: To determine extent oxidant/antioxidant imbalance and describe its determinants airways asthmatic children including severity genotype antioxidant enzymes. Methods: One hundred ten with mild asthma, 30 moderate 191 healthy controls were included study. Exhaled breath condensate (EBC) was collected from all EcoScreen ® ....
Background: Exhaled breath condensate (EBC) is a noninvasive method to obtain samples from fluids lining the respiratory surfaces. Even though various methods and devices are now available, relative efficiency of these for recovering airway mediators characterizing EBC has not been established. Aim: To compare volume, pH, lipid mediator, protein concentrations in EBCs collected by two commonly used commercially available devices, RTube TM ECoScreen. Methods: condensates were obtained...
To evaluate the efficacy and safety of clarithromycin treatment in preventing bronchopulmonary dysplasia (BPD) Ureaplasma urealyticum-positive preterm infants.Nasopharyngeal swabs for U urealyticum culture were taken from infants with a birth weight between 750 1250 g first 3 postnatal days. Infants positive randomly assigned to 1 2 groups receive either intravenous or placebo. All patients followed at least up 36th postmenstrual week.A total 224 met eligibility criteria study. Seventy-four...
<h3>Background</h3> Invasive fungal infections are a major cause of morbidity and mortality in preterm infants. The authors conducted the first prospective, randomised controlled trial nystatin compared with fluconazole for prevention colonisation invasive infection very low birth weight (VLBW) neonates. <h3>Methods</h3> During 12-month period, all VLBW neonates were assigned randomly to receive (1 ml suspension, 100 000 U/ml, every 8 h), (3 mg/kg body weight, third day) or placebo from...
To determine the effect of delivery type on macronutrient content colostral milk.The study was conducted at Zekai Tahir Burak Maternity Teaching Hospital. Colostral milk samples from term lactating mothers who gave birth by vaginal or cesarean (CD) were obtained 2nd postpartum day. Milk protein, fat, carbohydrate (CHO) and energy levels measured using a mid-infrared human analyzer.A total 204 recruited to study; 111 route 93 CD. Protein statistically lower in after CD compared delivered...
To evaluate the growth and neurodevelopment outcomes of very low-birth-weight (VLBW) preterm infants supplemented with oral probiotics for prevention necrotizing enterocolitis (NEC).This prospective follow-up study was conducted in a cohort VLBW enrolled randomized controlled clinical trial to efficacy NEC. Growth included weight, length, head circumference. Cognitive neuromotor development were assessed by using Bayley Scales Infant Development II. Sensory neurological performance evaluated...
We prospectively evaluated the differences in clinical responses and short-term outcomes preterm infants with respiratory distress syndrome (RDS) treated poractant alfa or beractant. Premature RDS were randomized to beractant treatment between July 2008 June 2009. Patients followed until 40 weeks of corrected gestational age death. The fraction inspired oxygen (F<sc>io</sc> <sub>2</sub>) after surfactant treatment, need for repeat doses, duration support hospitalization groups. Sixty-one...
We retrospectively reviewed the medical records of all Syrian immigrants from TurkishSyrian border who delivered Zekai Tahir Burak Maternity and Teaching Hospital Neonatal Intensive Care Unit (NICU) in Ankara, Turkey. Between January 2013 December 2014 a total 36,346 women gave birth at this center. Of these, 457 were immigrants, comprising 1.2 % (457/36,346) deliveries. The number births among refugees Turkey appears to be increasing. Further research is needed understand relative morbidity...
When the newborn brain is exposed to hypoxia, as in hypoxic ischemic encephalopathy (HIE), it causes an inflammatory response. A wide variety of markers are therefore used diagnosis HIE.
The aim of this study was to determine whether there an association between platelet parameters and the presence pulmonary hemorrhage (PH) in very low birth weight infants. Fifty preterm infants who developed PH with gestational age ≤30 weeks ≤1500 g were analyzed retrospectively. matched for birthweight without PH, served as control group. Groups compared terms demographic, clinical characteristics parameters. Red cell distribution width ratio (RPR) mass also calculated. A total 150...
Acute kidney injury (AKI) affects up to 60% of severely asphyxiated neonates. The diagnosis AKI can be and is further challenged by a lack good biomarkers. We studied the role novel markers for AKI, neutrophil gelatinase-associated lipocalin (NGAL), interleukin-8 (IL-18), Netrin-1 (NTN-1), sodium hydrogen exchanger isoform 3 (NHE3) on development early in newborns with perinatal asphyxia (PA).Forty-one PA (15 26 without AKI) 20 healthy matched controls were involved study. Urinary samples...
To investigate the association of systemic immune-inflammation index (SII) and immune-response (SIRI) with adverse perinatal outcomes in pregnant women coronavirus disease 2019 (COVID-19).The cases were divided into (1) Mild-moderate COVID-19 group (n = 2437) (2) Severe-critical 212). Clinical characteristics, outcomes, SII (neutrophilXplatelet/lymphocyte), SIRI (neutrophilXmonocyte/lymphocyte) compared between groups. Afterward, values subgroups based on pregnancy complications, neonatal...
Oxidative damage is important in the pathogenesis of respiratory distress syndrome (RDS). However, data on effect surfactant therapy oxidative stress vivo are limited. We aimed to evaluate oxidant/antioxidant status preterm infants with RDS via measurement total antioxidant capacity (TAC) and oxidant (TOS), determine balance assess association between TAC, TOS clinical outcomes patients.Sixty-nine were included. Blood samples for determining TAC collected before 48 h after treatment. levels...
Objective To determine the effect of two different feeding strategies on time to achieve full enteral and incidence intolerance in preterm infants with birth weight ≤1250 g.Methods A prospective randomized trial (NCT02913677) conducted at a tertiary level neonatal intensive care unit. Preterm g were randomly allocated either prolonged minimal nutrition (MEN) which feed volumes not increased for five days or early advancement groups advanced by 20–25 ml/kg/d until 150 volume was achieved. The...
Background: This study aimed to compare the effects of adjustable fortification (AF), targeted (TF), and standard (SF) methods on early growth very low birth weight infants. Materials Methods: Sixty infants <32 weeks gestational age weighing <1,500 g were selected. These exclusively fed with breast milk randomized into three groups: SF, AF, TF. SF consists adding a fixed amount fortifier maternal milk. Blood urea nitrogen levels are used adjust in AF. In TF, is analyzed fortified accordingly...
To determine total antioxidant capacity and oxidation status in fresh freeze stored (at -80°C) breast milk during the stages of lactation.Samples colostrum, transitional mature were collected from 44 healthy women at 3, 8 30 days after birth. The volume (6 ml) was divided two aliquot parts: 3 ml for analysis which done immediately extraction storage under freezing conditions -80°C months. oxidative stress assessed via determination status.Antioxidant decreased (p = 0.0001, p 0.028,...
We aimed to evaluate normal and pre-eclamptic placental vasculature by using CD31 Factor VIII. evaluated placentas of 37 women immunohistochemical staining with VIII antibodies. Individual microvessels in the tissues were counted at × 100 400 magnification. Microvessel counts lower patients compared healthy controls after (26.5 ± 5.7 vs 103.9 8.2, p < 0.001) (24.8 6.7 98.7 10.3, 0.001). Balance between proangiogenic antiangiogenic factors seems be shifted favour anti-angiogenic pre-eclampsia.
Purpose: To determine whether prophylaxis with etanercept, an anti-inflammatory drug, would decrease the severity of lung injury in a neonatal rat model bronchopulmonary dysplasia (BPD); Materials and Methods: Rat pups were divided into three groups: exposed to room air (group 1; n = 10), hyperoxia + placebo 2; 9), etanercept 3; 8). Lung morphology was assessed by alveolar surface area percentage, which is measure size. The severities inflammation antioxidant capacity quantifying tumor...