Hirotsugu Hamamoto

ORCID: 0000-0003-1202-8919
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About
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Research Areas
  • Cardiac Valve Diseases and Treatments
  • Cardiac Structural Anomalies and Repair
  • Cardiac Ischemia and Reperfusion
  • Cardiac electrophysiology and arrhythmias
  • Infective Endocarditis Diagnosis and Management
  • Cardiac Arrest and Resuscitation
  • Aortic aneurysm repair treatments
  • Aortic Disease and Treatment Approaches
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cardiovascular Function and Risk Factors
  • Infectious Aortic and Vascular Conditions
  • Mechanical Circulatory Support Devices
  • Cardiac Imaging and Diagnostics
  • Geothermal Energy Systems and Applications
  • Cardiac Fibrosis and Remodeling
  • Hemodynamic Monitoring and Therapy
  • Geological and Geophysical Studies
  • Cardiac pacing and defibrillation studies
  • Vascular Procedures and Complications
  • Cardiac tumors and thrombi
  • Tissue Engineering and Regenerative Medicine
  • Coronary Artery Anomalies
  • Geological Modeling and Analysis
  • Hydrocarbon exploration and reservoir analysis
  • Cardiac Health and Mental Health

Almeida Memorial Hospital
2015-2024

Medical University of South Carolina
2009-2011

University of Pennsylvania
2005-2011

Ralph H. Johnson VA Medical Center
2011

Oita University
2000-2010

Children's Hospital of Philadelphia
2010

Philadelphia University
2010

Columbia University
2009

Park Terrace Care Center
2006

American College of Surgeons
2005

Targeted delivery of mesenchymal precursor cells (MPCs) can modify left ventricular (LV) cellular and extracellular remodeling after myocardial infarction (MI). However, whether to what degree LV may be affected by MPC injection post-MI, these effects are concentration-dependent, remain unknown.Allogeneic MPCs were expanded from sheep bone marrow, direct intramyocardial was performed within the borderzone region 1 hour MI induction (coronary ligation) in at following concentrations: 25x10(6)...

10.1161/circulationaha.108.842302 article EN Circulation 2009-09-14

A digital filter for thoracic impedance cardiography was developed and implemented on a 16-bit personal computer after examining the effect of respiratory movement first derivative signal. Four male subjects exercised with cycle ergometer at 100 150 W successively, resting 5 min. Thoracic its (dZ/dt) were recorded by standard four-electrode cardiograph. The peak-power spectral densities pneumogenic (P/sub p,c/) cardiogenic components dZ/dt separated simultaneous recording ECG circumferences....

10.1109/10.8694 article EN IEEE Transactions on Biomedical Engineering 1988-01-01

Although localized delivery of biocomposite materials, such as calcium hydroxyapatite (CHAM), have been demonstrated to potentially attenuate adverse left ventricular (LV) remodeling after myocardial infarction (MI), the underlying biological mechanisms for this effect remain unclear. This study tested hypothesis that targeted CHAM injections would alter proteolytic pathways (matrix metalloproteinases [MMPs] and tissue inhibitors MMPs [TIMPs]) be associated with parameters post-MI LV...

10.1161/circulationaha.111.035774 article EN Circulation 2011-09-12

It is widely accepted that, during acute coronary occlusion, ischemic cell death progresses from the subendocardium to subepicardium in a wavefront fashion. This concept, which implies that most susceptible myocardial region injury, was established using canine model with an extensive system of subepicardial collaterals. In humans, particularly those artery disease, there wide range distribution and functional capacity collateral circulation, may affect pattern infarct evolution. Using ovine...

10.1152/ajpheart.00590.2007 article EN AJP Heart and Circulatory Physiology 2007-07-21

Abstract Background We report a rare case of giant right atrial myxoma after catheter ablation. Case presentation A 74-year-old man presented with fever unknown origin three years laser Multimodal imaging revealed tumor located in the atrium, which was suspected to be malignant. Surgical resection performed, and pathological examination that myxoma. Conclusions Several cardiac cases ablation have been reported, suggesting potential association between development ablation-related tissue injury.

10.1186/s44215-024-00145-7 article EN cc-by General Thoracic and Cardiovascular Surgery Cases 2024-02-27

The epicardial and endocardial conduction of premature impulses were studied during acute myocardial ischemia reperfusion.The left anterior descending artery was ligated below the second diagonal branch 30 minutes later, first branch; ligation released later.Five transmural electrode needles introduced into wal ventricle, each with an epicardial, a midwall bipole.During fixed atrial pacing, stimuli delivered at needle site in series.Conduction times defined as interval between pacing...

10.1161/01.cir.64.1.190 article EN Circulation 1981-07-01

Traumatic femoral artery occlusion caused by blunt impact to the groin is rare; this condition called "motor-scooter handlebar syndrome." We herein report a case of traumatic and performed literature review on its diagnosis treatment. An 18-year-old man visited our hospital complaining pain swelling in his right numbness leg after bicycle collision accident. Contrast computed tomography revealed an extending from external iliac common artery. The ankle–brachial index (ABI) was 0.50....

10.1186/s40792-019-0628-3 article EN cc-by Surgical Case Reports 2019-04-22

症例は72歳の男性.20年前に検診異常で診断された大動脈弁閉鎖不全症を近医で加療中に,下腿浮腫,体重増加でおおよそ2カ月間内服加療が行われるも症状の改善なく,当院の心臓超音波検査による精査で,無冠状動脈洞に生じたValsalva洞動脈瘤破裂,右房穿破の診断に至った.手術は発症から2カ月半後に待機的に計画され,人工心肺使用下に大動脈弁側と右房側の両側からのアプローチでパッチによる瘻孔閉鎖と,無冠尖の弁尖形態の変性による大動脈弁閉鎖不全症に対しては大動脈弁置換術で手術を完遂し,術後経過良好で術後14日目に自宅退院された.元来,左右シャントを形成し,重篤な心不全症状で発症することもある破裂性Valsalva洞動脈瘤は非常に稀な疾患である.発症機序は,先天的なValsalva洞の組織脆弱性が原因とされ,破裂に至る症例は40歳代ごろまでの比較的若年層であることが一般的である.本症例は72歳という高齢発症であり,さらに急激な心不全症状の進行なく,待機手術が可能であった非常に稀有な経過を辿った症例として,文献的考察も含め報告する.

10.4326/jjcvs.53.198 article EN Japanese Journal of Cardiovascular Surgery 2024-07-15

SAKO, H., et al.: An Implantation of DDD Epicardial Pacemaker Through Ministernotomy in a Patient with Superior Vena Cava Occlusion. We successfully implanted epicardial pacemaker through limited lower sternotomy patient whose superior vena cava had been occluded. Both leads were connected to the generator placed existing subcutaneous pocket on left pectoral region second intercostal space. This approach provided excellent exposure and easy access both right appendage ventricle. The combined...

10.1046/j.1460-9592.2003.00134_26_3.x article EN Pacing and Clinical Electrophysiology 2003-03-01
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